Calcium in PDB 1w8b: FACTOR7 - 413 Complex

All present enzymatic activity of FACTOR7 - 413 Complex:
3.4.21.21;

The structure of FACTOR7 - 413 Complex, PDB code: 1w8b was solved by J.Ackermann, L.Alig, D.W.Banner, H.-J.Boehm, K.Groebke-Zbinden, K.Hilpert, T.Lave, H.Kuehne, U.Obst-Sander, M.A.Riederer, M.Stahl, T.B.Tschopp, L.Weber, H.P.Wessel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	72.36 / 3.00
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	82.846, 82.846, 147.768, 90.00, 90.00, 90.00
R / Rfree (%)	19.4 / 27.2

The binding sites of Calcium atom in the FACTOR7 - 413 Complex (pdb code 1w8b). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the FACTOR7 - 413 Complex, PDB code: 1w8b:

Calcium binding site 1 out of 1 in the FACTOR7 - 413 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of FACTOR7 - 413 Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca1258 b:39.4 occ:1.00 O H:GLU75 2.2 32.3 1.0 OE2 H:GLU80 2.3 32.6 1.0 OE1 H:GLU70 2.3 36.2 1.0 O H:HOH2013 2.4 9.0 1.0 O H:ASP72 2.6 29.0 1.0 CD H:GLU80 3.3 32.5 1.0 C H:GLU75 3.3 32.2 1.0 CD H:GLU70 3.4 30.9 1.0 C H:ASP72 3.6 29.0 1.0 OE2 H:GLU70 3.7 30.8 1.0 CG H:GLU80 3.8 30.4 1.0 CA H:HIS76 3.9 31.8 1.0 N H:ASP72 3.9 28.2 1.0 N H:HIS76 4.0 32.0 1.0 N H:ASP77 4.1 31.2 1.0 CA H:ASP72 4.2 28.8 1.0 O H:HOH2014 4.3 26.4 1.0 OE1 H:GLU80 4.3 33.5 1.0 N H:HIS71 4.4 26.7 1.0 N H:GLU75 4.4 32.1 1.0 CA H:GLU75 4.4 32.5 1.0 C H:HIS76 4.5 31.5 1.0 N H:LEU73 4.5 29.4 1.0 CB H:ASP72 4.7 29.1 1.0 CG H:GLU70 4.7 28.7 1.0 CG H:GLU75 4.7 33.5 1.0 OD2 H:ASP77 4.7 31.6 1.0 CA H:LEU73 4.8 29.9 1.0 CG H:ASP77 4.8 31.3 1.0 C H:HIS71 4.9 27.6 1.0 CA H:GLU70 5.0 26.4 1.0

K.Groebke-Zbinden, U.Obst-Sander, K.Hilpert, H.Kuehne, D.W.Banner, H.-J.Boehm, M.Stahl, J.Ackermann, L.Alig, L.Weber, H.P.Wessel, M.A.Riederer, T.B.Tschopp, T.Lave. Selective and Orally Bioavailable Phenylglycine Tissue Factor/Factor Viia Inhibitors Bioorg.Med.Chem.Lett. V. 15 5344 2005.
ISSN: ISSN 0960-894X
PubMed: 16213138
DOI: 10.1016/J.BMCL.2005.04.079