Calcium in PDB 1xcw: Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts

Enzymatic activity of Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts

All present enzymatic activity of Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts:
3.2.1.1;

Protein crystallography data

The structure of Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts, PDB code: 1xcw was solved by C.Li, A.Begum, S.Numao, K.H.Park, S.G.Withers, G.D.Brayer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	10.00 / 2.00
*Space group*	P 2₁ 2₁ 2₁
*Cell size a, b, c (Å), α, β, γ (°)*	52.900, 69.000, 131.900, 90.00, 90.00, 90.00
*R / R_free (%)*	17.4 / 21.5

Other elements in 1xcw:

Chlorine

(Cl)

1 atom

Calcium Binding Sites:

The binding sites of Calcium atom in the Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts (pdb code 1xcw). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts, PDB code: 1xcw:

Calcium binding site 1 out of 1 in 1xcw

Go back to

Calcium Binding Sites List in 1xcw

Calcium binding site 1 out of 1 in the Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts

Mono view

Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Ca497 b:10.3 occ:1.00	OD2	A:ASP167	2.3	13.9	1.0
	O	A:ARG158	2.4	13.4	1.0
	OD1	A:ASN100	2.4	14.1	1.0
	O	A:HIS201	2.4	11.1	1.0
	OD1	A:ASP167	2.5	11.9	1.0
	CG	A:ASP167	2.7	13.2	1.0
	C	A:ARG158	3.5	14.0	1.0
	CG	A:ASN100	3.5	13.5	1.0
	C	A:HIS201	3.6	12.5	1.0
	ND2	A:ASN100	4.0	11.8	1.0
	CA	A:ARG158	4.1	14.8	1.0
	CB	A:HIS201	4.2	12.5	1.0
	CB	A:ASP167	4.2	11.1	1.0
	O	A:ASN100	4.4	13.2	1.0
	O	A:HOH543	4.4	14.4	1.0
	CA	A:HIS201	4.4	12.2	1.0
	O	A:CYS160	4.5	11.9	1.0
	N	A:ASP159	4.6	12.6	1.0
	N	A:MET202	4.6	11.5	1.0
	ND2	A:ASN137	4.6	16.5	1.0
	CA	A:MET202	4.7	12.1	1.0
	CG	A:MET202	4.8	11.4	1.0
	O	A:VAL157	4.8	14.6	1.0
	CB	A:ASN100	4.8	12.7	1.0
	O	A:LEU168	4.8	14.9	1.0
	CA	A:ASP159	4.9	15.4	1.0
	O	A:HOH526	4.9	11.8	1.0
	CB	A:ARG158	5.0	15.5	1.0

Reference:

C.Li, A.Begum, S.Numao, K.H.Park, S.G.Withers, G.D.Brayer. Acarbose Rearrangement Mechanism Implied By the Kinetic and Structural Analysis of Human Pancreatic Alpha-Amylase in Complex with Analogues and Their Elongated Counterparts Biochemistry V. 44 3347 2005.
ISSN: ISSN 0006-2960
PubMed: 15736945
DOI: 10.1021/BI048334E

Page generated: Sat Dec 12 03:26:44 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy