Calcium in PDB 1xhb: The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1

All present enzymatic activity of The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1:
2.4.1.41;

The structure of The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1, PDB code: 1xhb was solved by T.A.Fritz, J.H.Hurley, L.B.Trinh, J.Shiloach, L.A.Tabak, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.39 / 2.50
Space group	P 43
Cell size a, b, c (Å), α, β, γ (°)	65.605, 65.605, 125.947, 90.00, 90.00, 90.00
R / Rfree (%)	21.8 / 25.5

The structure of The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1 also contains other interesting chemical elements:

Manganese

(Mn)

1 atom

The binding sites of Calcium atom in the The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1 (pdb code 1xhb). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1, PDB code: 1xhb:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca601 b:36.1 occ:1.00 OE1 A:GLU507 2.1 30.1 1.0 O A:TYR508 2.4 28.1 1.0 CD A:GLU507 3.2 31.7 1.0 C A:TYR508 3.6 29.3 1.0 OE2 A:GLU507 3.8 32.5 1.0 NZ A:LYS474 3.8 34.6 1.0 N A:TYR508 4.1 29.0 1.0 CA A:TYR508 4.3 28.8 1.0 CG A:GLU507 4.4 29.4 1.0 CD A:PRO510 4.4 32.4 1.0 N A:ASP509 4.6 30.8 1.0 CB A:TYR508 4.8 28.4 1.0 CA A:ASP509 4.8 31.0 1.0 C A:GLU507 5.0 28.1 1.0 OH A:TYR470 5.0 26.4 1.0

Calcium binding site 2 out of 2 in the The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of The Crystal Structure of Udp-Galnac: Polypeptide Alpha-N- Acetylgalactosaminyltransferase-T1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca602 b:55.5 occ:1.00 NH2 A:ARG399 3.7 28.9 1.0 OG A:SER398 3.8 43.8 1.0 CD A:ARG399 4.9 32.6 1.0 CZ A:ARG399 4.9 31.9 1.0

T.A.Fritz, J.H.Hurley, L.B.Trinh, J.Shiloach, L.A.Tabak. The Beginnings of Mucin Biosynthesis: the Crystal Structure of Udp-Galnac:Polypeptide {Alpha}-N-Acetylgalactosaminyltransferase-T1 Proc.Natl.Acad.Sci.Usa V. 101 15307 2004.
ISSN: ISSN 0027-8424
PubMed: 15486088
DOI: 10.1073/PNAS.0405657101