Calcium in PDB 1yo8: Structure of the C-Terminal Domain of Human Thrombospondin-2

The structure of Structure of the C-Terminal Domain of Human Thrombospondin-2, PDB code: 1yo8 was solved by C.B.Carlson, D.A.Bernstein, D.S.Annis, T.M.Misenheimer, B.A.Hannah, D.F.Mosher, J.L.Keck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.60
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	93.437, 121.588, 155.330, 90.00, 90.00, 90.00
R / Rfree (%)	21.8 / 28.4

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30;

Binding sites:

The binding sites of Calcium atom in the Structure of the C-Terminal Domain of Human Thrombospondin-2 (pdb code 1yo8). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 30 binding sites of Calcium where determined in the Structure of the C-Terminal Domain of Human Thrombospondin-2, PDB code: 1yo8:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1182 b:46.9 occ:1.00 O A:CYS948 2.3 49.5 1.0 O A:ILE954 2.3 51.7 1.0 OD2 A:ASP939 2.3 51.2 1.0 O A:ASN951 2.3 50.7 1.0 OD2 A:ASP937 2.3 50.2 1.0 OD2 A:ASP946 2.4 46.3 1.0 OD1 A:ASP946 2.6 46.2 1.0 OG A:SER955 2.8 54.9 1.0 CG A:ASP946 2.9 47.1 1.0 C A:CYS948 3.3 49.8 1.0 C A:ILE954 3.4 51.2 1.0 C A:ASN951 3.4 51.6 1.0 CG A:ASP937 3.4 52.3 1.0 CG A:ASP939 3.5 52.0 1.0 OD1 A:ASP937 3.8 51.2 1.0 CB A:SER955 3.9 53.7 1.0 CA A:SER955 4.0 53.0 1.0 OD1 A:ASP939 4.0 51.6 1.0 N A:SER955 4.1 52.0 1.0 N A:PRO949 4.2 50.1 1.0 CA A:CYS948 4.2 49.3 1.0 CB A:CYS948 4.2 49.1 1.0 N A:ASN952 4.2 52.0 1.0 CA A:ASN952 4.2 53.2 1.0 N A:ASN951 4.2 51.4 1.0 CA A:CA1183 4.2 50.2 1.0 CA A:PRO949 4.3 51.2 1.0 CA A:ASN951 4.3 51.5 1.0 N A:ILE954 4.3 50.6 1.0 CB A:ASP946 4.4 49.0 1.0 CA A:ILE954 4.4 50.1 1.0 N A:CYS948 4.4 48.5 1.0 C A:PRO949 4.6 52.1 1.0 C A:ASN952 4.6 52.7 1.0 CB A:ASP937 4.7 54.3 1.0 CB A:ASP939 4.7 52.0 1.0 CB A:ASN951 4.8 50.6 1.0 O A:HOH1266 4.8 51.5 1.0 O A:HOH1224 4.9 41.6 1.0 O A:PRO949 4.9 53.3 1.0 N A:GLU950 5.0 52.2 1.0

Calcium binding site 2 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1183 b:50.2 occ:1.00 O A:ILE941 2.2 55.6 1.0 O A:HOH1266 2.3 51.5 1.0 OD1 A:ASP939 2.3 51.6 1.0 OD1 A:ASP935 2.3 58.5 1.0 OD1 A:ASP937 2.3 51.2 1.0 OD2 A:ASP946 2.5 46.3 1.0 CG A:ASP939 3.3 52.0 1.0 CG A:ASP937 3.4 52.3 1.0 C A:ILE941 3.4 55.7 1.0 CG A:ASP935 3.5 60.3 1.0 CG A:ASP946 3.5 47.1 1.0 OD2 A:ASP939 3.6 51.2 1.0 OD2 A:ASP937 3.7 50.2 1.0 CB A:ASP946 3.9 49.0 1.0 N A:ILE941 4.1 55.5 1.0 CA A:ILE941 4.1 55.2 1.0 N A:ASP939 4.2 54.3 1.0 CA A:CA1182 4.2 46.9 1.0 CA A:ASP935 4.3 60.2 1.0 OD2 A:ASP935 4.3 61.9 1.0 CB A:ILE941 4.3 54.7 1.0 C A:PRO942 4.4 55.2 1.0 CB A:ASP935 4.4 60.4 1.0 N A:PRO942 4.4 56.1 1.0 N A:ASP937 4.5 55.9 1.0 C A:ASP935 4.5 59.5 1.0 N A:ASP943 4.5 55.1 1.0 N A:ASN938 4.5 55.3 1.0 CB A:ASP939 4.6 52.0 1.0 O A:PRO942 4.6 54.3 1.0 OD1 A:ASP946 4.6 46.2 1.0 O A:PRO949 4.6 53.3 1.0 CA A:PRO942 4.6 56.1 1.0 OD1 A:ASP943 4.7 56.4 1.0 CB A:ASP937 4.7 54.3 1.0 CA A:PRO949 4.7 51.2 1.0 N A:ASN940 4.7 54.7 1.0 OG A:SER955 4.8 54.9 1.0 CA A:ASP939 4.8 53.4 1.0 N A:PHE936 4.8 58.5 1.0 O A:ASP935 4.8 59.0 1.0 C A:ASP937 4.9 54.8 1.0 CA A:ASP937 4.9 54.9 1.0 C A:ASP939 4.9 53.4 1.0

Calcium binding site 3 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1184 b:74.0 occ:1.00 OD1 A:ASP926 2.1 70.2 1.0 O A:ARG928 2.4 68.5 1.0 OD1 A:ASP930 2.4 69.0 1.0 OD1 A:ASP922 2.5 69.5 1.0 OD1 A:ASP924 2.5 77.1 1.0 CG A:ASP926 3.1 69.2 1.0 CG A:ASP924 3.4 76.2 1.0 OD2 A:ASP926 3.4 67.6 1.0 OD2 A:ASP924 3.4 76.6 1.0 C A:ARG928 3.6 67.4 1.0 CG A:ASP930 3.6 68.8 1.0 CG A:ASP922 3.6 70.7 1.0 N A:ASP930 3.8 66.5 1.0 CA A:ASP930 3.9 66.4 1.0 C A:GLY929 4.0 66.3 1.0 CA A:ASP922 4.2 71.5 1.0 CB A:ASP930 4.3 67.5 1.0 CB A:ASP926 4.3 70.8 1.0 O A:GLY929 4.3 66.1 1.0 CB A:ASP922 4.3 71.2 1.0 CA A:ARG928 4.4 67.1 1.0 CB A:ARG928 4.4 66.5 1.0 N A:ARG928 4.4 67.9 1.0 N A:ASP926 4.4 72.6 1.0 OD2 A:ASP922 4.4 70.6 1.0 OD2 A:ASP930 4.5 69.1 1.0 N A:GLY929 4.5 66.5 1.0 CA A:GLY929 4.6 66.5 1.0 C A:ASP922 4.7 72.8 1.0 N A:LEU923 4.8 73.8 1.0 CA A:ASP926 4.8 71.3 1.0 N A:ASP924 4.8 76.2 1.0 CB A:ASP924 4.8 76.5 1.0

Calcium binding site 4 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1185 b:57.8 occ:1.00 OD1 A:ASP901 2.2 60.3 1.0 OD1 A:ASP903 2.3 63.4 1.0 OD2 A:ASP910 2.3 64.2 1.0 O A:HOH1268 2.4 54.4 1.0 O A:VAL905 2.4 65.3 1.0 OD1 A:ASP899 2.5 62.2 1.0 CG A:ASP901 3.3 59.7 1.0 CG A:ASP903 3.3 62.5 1.0 CG A:ASP910 3.4 65.2 1.0 C A:VAL905 3.6 66.0 1.0 OD2 A:ASP901 3.6 60.9 1.0 CG A:ASP899 3.7 62.2 1.0 OD2 A:ASP903 3.7 60.6 1.0 CB A:ASP910 4.1 65.9 1.0 N A:ASP903 4.2 62.0 1.0 CA A:CA1186 4.2 58.4 1.0 O A:ARG913 4.2 59.6 1.0 N A:ASP901 4.2 58.3 1.0 OD2 A:ASP899 4.4 63.5 1.0 N A:VAL905 4.4 66.2 1.0 CA A:VAL905 4.4 66.2 1.0 CA A:ASP899 4.4 61.5 1.0 N A:ASP900 4.4 59.1 1.0 OD1 A:ASP910 4.4 65.9 1.0 C A:PRO906 4.5 66.2 1.0 CB A:ASP903 4.5 62.7 1.0 C A:ASP899 4.6 60.6 1.0 N A:PRO906 4.6 66.7 1.0 CB A:ASP901 4.6 58.8 1.0 OD1 A:ASP907 4.6 64.4 1.0 N A:ASN902 4.6 59.9 1.0 CB A:VAL905 4.6 65.9 1.0 CB A:ASP899 4.6 62.4 1.0 CA A:PRO906 4.7 66.5 1.0 CA A:ASP903 4.7 63.3 1.0 O A:PRO906 4.7 66.2 1.0 N A:ASP907 4.7 66.1 1.0 CA A:ASP901 4.8 58.7 1.0 C A:ASP903 4.9 64.4 1.0 N A:GLY904 4.9 64.8 1.0 C A:ASP901 4.9 59.6 1.0 C A:ARG913 5.0 60.0 1.0

Calcium binding site 5 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1186 b:58.4 occ:1.00 OD2 A:ASP903 2.2 60.6 1.0 O A:CYS912 2.3 61.5 1.0 OD1 A:ASN917 2.3 62.8 1.0 OD2 A:ASP901 2.4 60.9 1.0 O A:VAL915 2.4 62.5 1.0 OD1 A:ASP910 2.6 65.9 1.0 OD2 A:ASP910 2.6 64.2 1.0 CG A:ASP910 3.0 65.2 1.0 C A:CYS912 3.3 61.3 1.0 CG A:ASP903 3.3 62.5 1.0 CG A:ASP901 3.5 59.7 1.0 C A:VAL915 3.5 62.1 1.0 CG A:ASN917 3.5 63.8 1.0 N A:ASN917 3.6 65.8 1.0 OD1 A:ASP903 3.8 63.4 1.0 CB A:CYS912 3.8 61.9 1.0 OD1 A:ASP901 3.9 60.3 1.0 NE2 A:GLN920 4.0 66.9 1.0 CA A:CYS912 4.0 61.8 1.0 CA A:CA1185 4.2 57.8 1.0 C A:PHE916 4.2 65.3 1.0 N A:CYS912 4.2 62.4 1.0 N A:PHE916 4.3 62.8 1.0 CA A:PHE916 4.3 64.2 1.0 N A:VAL915 4.3 60.7 1.0 N A:ARG913 4.3 60.6 1.0 CA A:ASN917 4.4 66.3 1.0 ND2 A:ASN917 4.4 62.7 1.0 C A:ARG913 4.4 60.0 1.0 CB A:ASN917 4.5 65.8 1.0 CB A:ASP910 4.5 65.9 1.0 CA A:VAL915 4.5 61.1 1.0 O A:ARG913 4.5 59.6 1.0 CA A:ARG913 4.5 60.6 1.0 CB A:ASP903 4.6 62.7 1.0 O A:ASN917 4.6 67.0 1.0 C A:ASN917 4.7 67.2 1.0 CB A:ASP901 4.8 58.8 1.0 N A:LEU914 4.9 59.6 1.0

Calcium binding site 6 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1187 b:70.1 occ:1.00 OD2 A:ASP897 2.2 60.0 1.0 O A:ASP899 2.4 61.2 1.0 OD1 A:ASN902 2.5 59.0 1.0 OD2 A:ASP890 2.5 61.1 1.0 OD1 A:ASP897 2.6 61.9 1.0 OD2 A:ASP888 2.6 58.4 1.0 CG A:ASP897 2.7 61.2 1.0 O A:HOH1235 2.9 48.4 1.0 CG A:ASN902 3.4 58.5 1.0 C A:ASP899 3.4 60.6 1.0 CG A:ASP890 3.7 62.0 1.0 CG A:ASP888 3.8 58.5 1.0 ND2 A:ASN902 3.9 55.3 1.0 CA A:CA1188 3.9 55.9 1.0 CB A:ASP899 4.0 62.4 1.0 OD1 A:ASP890 4.1 61.5 1.0 CA A:ASP899 4.2 61.5 1.0 CB A:ASP897 4.2 61.5 1.0 OD1 A:ASP888 4.2 58.0 1.0 N A:ASP899 4.3 61.8 1.0 N A:ASP900 4.4 59.1 1.0 N A:ASN902 4.5 59.9 1.0 CA A:ASP900 4.6 58.2 1.0 CB A:ASN902 4.6 59.6 1.0 CA A:ASN902 4.7 60.5 1.0 CG A:ASP899 4.8 62.2 1.0 C A:ASP900 4.8 58.0 1.0 CB A:ASP890 5.0 62.0 1.0 OE1 A:GLN892 5.0 69.9 1.0 CB A:ASP888 5.0 59.3 1.0

Calcium binding site 7 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1188 b:55.9 occ:1.00 O A:GLN892 2.2 57.9 1.0 OD1 A:ASP890 2.4 61.5 1.0 OD2 A:ASP897 2.4 60.0 1.0 OD1 A:ASP888 2.4 58.0 1.0 OD1 A:ASP886 2.5 59.5 1.0 CG A:ASP888 3.2 58.5 1.0 OD2 A:ASP888 3.2 58.4 1.0 CG A:ASP890 3.2 62.0 1.0 C A:GLN892 3.3 58.8 1.0 OD2 A:ASP890 3.4 61.1 1.0 CG A:ASP897 3.4 61.2 1.0 CG A:ASP886 3.6 57.9 1.0 CB A:ASP897 3.8 61.5 1.0 CA A:CA1187 3.9 70.1 1.0 CA A:GLN892 4.0 60.1 1.0 N A:GLN892 4.1 60.1 1.0 CB A:GLN892 4.2 61.0 1.0 N A:ASP890 4.3 61.6 1.0 OD2 A:ASP886 4.3 59.8 1.0 N A:GLY893 4.4 58.0 1.0 CB A:ASP890 4.5 62.0 1.0 C A:GLY893 4.5 57.3 1.0 OD1 A:ASP897 4.5 61.9 1.0 N A:ASP894 4.6 56.5 1.0 CB A:ASP888 4.6 59.3 1.0 CA A:ASP886 4.6 55.0 1.0 N A:ASP888 4.7 58.0 1.0 CB A:ASP886 4.7 54.8 1.0 CA A:GLY893 4.7 57.2 1.0 O A:ASP900 4.7 57.8 1.0 OD1 A:ASP894 4.7 55.4 1.0 CA A:ASP890 4.7 61.9 1.0 N A:GLY891 4.7 60.7 1.0 C A:ASP886 4.8 55.2 1.0 N A:ARG889 4.8 60.0 1.0 O A:GLY893 4.8 58.0 1.0 C A:ASP890 4.9 62.0 1.0 CA A:ASP900 4.9 58.2 1.0 O A:ASP899 5.0 61.2 1.0 CA A:ASP888 5.0 59.1 1.0

Calcium binding site 8 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1189 b:61.5 occ:1.00 OD2 A:ASP907 2.0 63.1 1.0 O A:ASP897 2.2 62.0 1.0 O A:ASP894 2.2 58.6 1.0 O A:HOH1226 2.3 45.1 1.0 OD1 A:ASP900 2.6 56.9 1.0 OD2 A:ASP900 2.8 56.8 1.0 O A:HOH1249 2.9 49.6 1.0 CG A:ASP900 3.0 57.6 1.0 CG A:ASP907 3.3 64.6 1.0 C A:ASP894 3.3 58.1 1.0 C A:ASP897 3.4 62.5 1.0 OD1 A:ASP907 4.0 64.4 1.0 CA A:ASP894 4.0 57.0 1.0 N A:ASP897 4.2 62.8 1.0 CA A:ASP897 4.3 62.4 1.0 N A:PRO898 4.3 63.1 1.0 CB A:ASP907 4.3 65.5 1.0 CA A:PRO898 4.4 63.3 1.0 N A:ALA895 4.4 58.3 1.0 CB A:ASP900 4.5 57.9 1.0 CB A:ASP894 4.6 56.0 1.0 C A:ALA895 4.7 61.0 1.0 CB A:ASP897 4.7 61.5 1.0 C A:PRO898 4.7 62.8 1.0 CA A:ALA895 4.7 59.6 1.0 N A:ASP899 4.8 61.8 1.0 O A:ALA895 4.8 62.1 1.0 N A:ASP900 4.9 59.1 1.0 N A:CYS896 5.0 61.7 1.0

Calcium binding site 9 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1190 b:63.2 occ:1.00 OD2 A:ASP867 2.2 46.5 1.0 O A:ILE879 2.2 56.0 1.0 OD2 A:ASP865 2.3 59.6 1.0 O A:CYS876 2.4 61.0 1.0 OD2 A:ASP874 2.5 55.2 1.0 OD1 A:ASN881 2.5 51.9 1.0 OD1 A:ASP874 2.7 57.8 1.0 CG A:ASP874 3.0 57.6 1.0 C A:ILE879 3.2 57.2 1.0 CG A:ASP867 3.4 48.6 1.0 N A:ASN881 3.4 50.9 1.0 CG A:ASP865 3.4 57.7 1.0 C A:CYS876 3.5 61.3 1.0 CG A:ASN881 3.7 50.2 1.0 CA A:SER880 3.7 53.9 1.0 OD1 A:ASP865 3.7 57.3 1.0 C A:SER880 3.8 52.5 1.0 N A:SER880 3.9 55.9 1.0 OD1 A:ASP867 3.9 46.9 1.0 CB A:CYS876 4.0 61.3 1.0 CA A:CA1191 4.2 53.1 1.0 CA A:CYS876 4.2 61.3 1.0 NE2 A:GLN884 4.2 48.8 1.0 N A:ILE879 4.2 60.6 1.0 CA A:ASN881 4.4 49.9 1.0 CA A:ILE879 4.4 58.9 1.0 CB A:ASN881 4.4 50.6 1.0 N A:PRO877 4.5 62.0 1.0 N A:CYS876 4.5 59.9 1.0 C A:PRO877 4.5 62.0 1.0 CB A:ASP874 4.5 57.4 1.0 CB A:ASP867 4.5 47.8 1.0 CA A:PRO877 4.6 61.9 1.0 ND2 A:ASN881 4.7 49.2 1.0 O A:PRO877 4.7 61.8 1.0 CB A:ASP865 4.7 57.0 1.0 N A:TYR878 4.7 62.5 1.0 O A:SER880 4.8 52.0 1.0 C A:ASN881 4.8 49.3 1.0 O A:ASN881 4.9 49.4 1.0 O A:HOH1325 5.0 75.0 1.0

Calcium binding site 10 out of 30 in the Structure of the C-Terminal Domain of Human Thrombospondin-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Structure of the C-Terminal Domain of Human Thrombospondin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1191 b:53.1 occ:1.00 OD1 A:ASP863 2.0 58.5 1.0 O A:HIS869 2.2 50.0 1.0 OD1 A:ASP865 2.3 57.3 1.0 O A:HOH1325 2.3 75.0 1.0 OD1 A:ASP867 2.4 46.9 1.0 OD2 A:ASP874 2.4 55.2 1.0 CG A:ASP863 3.3 57.2 1.0 CG A:ASP867 3.3 48.6 1.0 CG A:ASP865 3.4 57.7 1.0 C A:HIS869 3.4 50.1 1.0 CG A:ASP874 3.5 57.6 1.0 OD2 A:ASP867 3.6 46.5 1.0 OD2 A:ASP865 3.7 59.6 1.0 N A:HIS869 3.9 48.6 1.0 OD2 A:ASP863 4.0 54.0 1.0 CB A:ASP874 4.1 57.4 1.0 CA A:HIS869 4.1 49.4 1.0 CA A:CA1190 4.2 63.2 1.0 CB A:ASP863 4.2 57.7 1.0 N A:ASP867 4.3 48.5 1.0 CB A:HIS869 4.4 49.3 1.0 CA A:ASP863 4.4 59.2 1.0 N A:ASP865 4.4 57.8 1.0 N A:GLN870 4.4 51.0 1.0 C A:GLN870 4.4 54.3 1.0 O A:PRO877 4.5 61.8 1.0 OD1 A:ASP874 4.5 57.8 1.0 CA A:GLN870 4.6 52.6 1.0 O A:GLN870 4.6 54.8 1.0 N A:GLY868 4.6 48.2 1.0 C A:ASP863 4.6 59.5 1.0 CB A:ASP867 4.6 47.8 1.0 CB A:ASP865 4.6 57.0 1.0 N A:ASP866 4.7 53.4 1.0 N A:ASN871 4.8 56.1 1.0 OD1 A:ASN871 4.8 59.0 1.0 CA A:ASP867 4.8 47.8 1.0 CA A:ASP865 4.8 56.5 1.0 N A:ILE864 4.9 59.8 1.0 C A:ASP865 4.9 54.5 1.0 C A:ASP867 4.9 47.6 1.0 O A:ASP863 5.0 59.4 1.0

C.B.Carlson, D.A.Bernstein, D.S.Annis, T.M.Misenheimer, B.L.Hannah, D.F.Mosher, J.L.Keck. Structure of the Calcium-Rich Signature Domain of Human Thrombospondin-2 Nat.Struct.Mol.Biol. V. 12 910 2005.
ISSN: ISSN 1545-9993
PubMed: 16186819
DOI: 10.1038/NSMB997