Calcium in PDB 1z3s: Angiopoietin-2 Receptor Binding Domain

The structure of Angiopoietin-2 Receptor Binding Domain, PDB code: 1z3s was solved by W.A.Barton, D.Tzvetkova, D.B.Nikolov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.35
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	74.190, 136.448, 47.732, 90.00, 93.43, 90.00
R / Rfree (%)	22.9 / 28.7

The binding sites of Calcium atom in the Angiopoietin-2 Receptor Binding Domain (pdb code 1z3s). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Angiopoietin-2 Receptor Binding Domain, PDB code: 1z3s:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Angiopoietin-2 Receptor Binding Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Angiopoietin-2 Receptor Binding Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca497 b:31.3 occ:1.00 O A:CYS435 2.3 22.9 1.0 O A:CYS433 2.3 32.1 1.0 OD2 A:ASP429 2.3 28.6 1.0 OD1 A:ASP431 2.5 25.5 1.0 OD1 A:ASP429 2.7 26.4 1.0 CG A:ASP429 2.8 26.1 1.0 CG A:ASP431 3.2 26.2 1.0 C A:CYS433 3.4 31.0 1.0 OD2 A:ASP431 3.4 25.7 1.0 C A:CYS435 3.4 24.8 1.0 O A:HOH70 3.8 31.3 1.0 N A:CYS433 4.0 31.3 1.0 N A:CYS435 4.1 28.8 1.0 CA A:CYS433 4.1 31.4 1.0 O A:ASP431 4.1 27.9 1.0 C A:ILE434 4.2 30.4 1.0 N A:LYS436 4.2 24.7 1.0 CA A:LYS436 4.2 24.4 1.0 CB A:CYS433 4.3 31.8 1.0 CB A:ASP429 4.3 25.9 1.0 CA A:CYS435 4.4 26.9 1.0 N A:ILE434 4.4 31.8 1.0 C A:ASP431 4.5 26.9 1.0 O A:ILE434 4.5 30.6 1.0 CB A:ASP431 4.6 25.5 1.0 CA A:ILE434 4.6 32.2 1.0 N A:ASP431 4.6 24.7 1.0 CA A:ASP431 4.8 25.7 1.0

Calcium binding site 2 out of 2 in the Angiopoietin-2 Receptor Binding Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Angiopoietin-2 Receptor Binding Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca497 b:36.8 occ:1.00 O B:CYS433 2.3 29.7 1.0 O B:CYS435 2.3 21.2 1.0 OD1 B:ASP431 2.5 29.7 1.0 OD2 B:ASP429 2.5 35.1 1.0 OD1 B:ASP429 2.6 31.5 1.0 CG B:ASP429 2.9 30.9 1.0 CG B:ASP431 3.3 29.6 1.0 C B:CYS433 3.4 29.9 1.0 C B:CYS435 3.4 24.3 1.0 OD2 B:ASP431 3.6 27.1 1.0 N B:CYS435 4.0 27.6 1.0 C B:ILE434 4.1 29.0 1.0 N B:CYS433 4.1 31.9 1.0 CA B:CYS433 4.2 30.5 1.0 N B:LYS436 4.3 23.6 1.0 CA B:CYS435 4.3 25.4 1.0 CB B:CYS433 4.3 29.1 1.0 CB B:ASP429 4.3 30.5 1.0 CA B:LYS436 4.4 25.8 1.0 N B:ILE434 4.4 29.3 1.0 O B:ILE434 4.4 29.7 1.0 O B:ASP431 4.5 30.9 1.0 CA B:ILE434 4.5 29.8 1.0 C B:ASP431 4.7 29.7 1.0 N B:ASP431 4.7 28.5 1.0 CB B:ASP431 4.7 28.2 1.0 CA B:ASP431 4.9 28.6 1.0

W.A.Barton, D.Tzvetkova, D.B.Nikolov. Structure of the Angiopoietin-2 Receptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition. Structure V. 13 825 2005.
ISSN: ISSN 0969-2126
PubMed: 15893672
DOI: 10.1016/J.STR.2005.03.009