Calcium in PDB 1z3u: Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition

The structure of Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition, PDB code: 1z3u was solved by W.A.Barton, D.Tzvetkova, D.B.Nikolov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.25
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	140.218, 94.468, 84.673, 90.00, 94.47, 90.00
R / Rfree (%)	24.6 / 27.8

The binding sites of Calcium atom in the Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition (pdb code 1z3u). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition, PDB code: 1z3u:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca497 b:25.0 occ:1.00 OD2 A:ASP429 2.3 19.6 1.0 O A:CYS435 2.3 22.2 1.0 OD1 A:ASP431 2.4 14.5 1.0 OD1 A:ASP429 2.5 19.1 1.0 O A:CYS433 2.5 17.9 1.0 O A:HOH529 2.6 19.2 1.0 CG A:ASP429 2.7 20.4 1.0 CG A:ASP431 3.1 16.3 1.0 OD2 A:ASP431 3.3 16.9 1.0 C A:CYS435 3.5 21.5 1.0 C A:CYS433 3.6 19.9 1.0 O A:ILE434 4.1 23.2 1.0 N A:CYS433 4.1 18.0 1.0 C A:ILE434 4.1 21.4 1.0 CB A:ASP429 4.2 18.1 1.0 CA A:CYS433 4.2 18.6 1.0 CB A:CYS433 4.3 18.6 1.0 N A:CYS435 4.3 21.4 1.0 O A:ASP431 4.3 15.6 1.0 CA A:LYS436 4.3 22.5 1.0 N A:LYS436 4.3 22.6 1.0 O A:HOH535 4.5 26.9 1.0 CA A:CYS435 4.5 21.1 1.0 CB A:ASP431 4.5 14.1 1.0 N A:ILE434 4.5 20.7 1.0 C A:ASP431 4.6 16.3 1.0 N A:ASP431 4.6 16.1 1.0 CA A:ILE434 4.7 22.1 1.0 CA A:ASP431 4.8 16.6 1.0

Calcium binding site 2 out of 4 in the Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca497 b:39.3 occ:1.00 O B:CYS435 2.2 29.9 1.0 OD1 B:ASP431 2.4 27.2 1.0 O B:CYS433 2.5 30.1 1.0 OD1 B:ASP429 2.6 34.5 1.0 OD2 B:ASP429 2.7 33.1 1.0 CG B:ASP429 3.0 33.6 1.0 CG B:ASP431 3.3 26.6 1.0 C B:CYS435 3.4 31.8 1.0 OD2 B:ASP431 3.4 26.9 1.0 C B:CYS433 3.5 31.0 1.0 N B:CYS433 4.0 29.7 1.0 O B:ILE434 4.1 34.1 1.0 C B:ILE434 4.1 32.8 1.0 CA B:CYS433 4.1 30.2 1.0 CB B:CYS433 4.2 28.8 1.0 N B:CYS435 4.2 32.3 1.0 N B:LYS436 4.3 32.6 1.0 CA B:LYS436 4.3 32.6 1.0 CA B:CYS435 4.4 31.9 1.0 O B:ASP431 4.5 27.5 1.0 N B:ILE434 4.5 32.1 1.0 CB B:ASP429 4.5 33.0 1.0 C B:ASP431 4.6 29.1 1.0 CB B:ASP431 4.6 26.4 1.0 CA B:ILE434 4.7 34.1 1.0 N B:ASP431 4.8 26.7 1.0 CG B:LYS436 4.9 36.0 1.0 CA B:ASP431 4.9 27.9 1.0

Calcium binding site 3 out of 4 in the Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca497 b:40.2 occ:1.00 O C:HOH557 2.3 35.9 1.0 OD1 C:ASP431 2.4 23.6 1.0 OD2 C:ASP429 2.5 31.7 1.0 O C:CYS433 2.5 31.0 1.0 O C:CYS435 2.6 28.6 1.0 OD1 C:ASP429 2.6 32.6 1.0 CG C:ASP429 2.9 31.3 1.0 CG C:ASP431 3.3 22.0 1.0 O C:ASP431 3.4 25.4 1.0 C C:CYS433 3.5 31.6 1.0 OD2 C:ASP431 3.6 24.4 1.0 C C:CYS435 3.7 30.6 1.0 N C:CYS433 4.0 29.4 1.0 C C:ASP431 4.1 24.3 1.0 CA C:CYS433 4.2 30.2 1.0 CB C:CYS433 4.3 29.4 1.0 N C:CYS435 4.4 33.6 1.0 N C:ASP431 4.4 23.1 1.0 CA C:LYS436 4.4 32.3 1.0 CB C:ASP429 4.4 29.0 1.0 O C:HOH598 4.5 45.6 1.0 C C:ILE434 4.5 35.2 1.0 N C:LYS436 4.5 31.3 1.0 CB C:ASP431 4.5 22.1 1.0 N C:ILE434 4.6 33.7 1.0 CA C:ASP431 4.6 23.0 1.0 CA C:CYS435 4.7 32.0 1.0 CA C:ILE434 4.8 35.7 1.0 O C:ILE434 4.8 37.0 1.0 C C:LYS432 4.9 28.8 1.0 N C:LYS432 5.0 27.9 1.0

Calcium binding site 4 out of 4 in the Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca497 b:35.4 occ:1.00 O D:CYS435 2.3 26.9 1.0 OD1 D:ASP429 2.4 28.9 1.0 OD1 D:ASP431 2.5 26.3 1.0 OD2 D:ASP429 2.6 30.1 1.0 CG D:ASP429 2.9 29.9 1.0 O D:CYS433 2.9 30.7 1.0 CG D:ASP431 3.2 26.4 1.0 OD2 D:ASP431 3.4 23.1 1.0 C D:CYS435 3.5 29.2 1.0 C D:CYS433 3.7 32.0 1.0 N D:CYS433 4.1 30.1 1.0 CB D:CYS433 4.1 30.8 1.0 CA D:CYS433 4.2 30.5 1.0 CA D:LYS436 4.3 30.5 1.0 N D:LYS436 4.3 29.5 1.0 CB D:ASP429 4.3 27.8 1.0 N D:CYS435 4.3 32.5 1.0 O D:ASP431 4.4 27.9 1.0 C D:ILE434 4.4 34.3 1.0 O D:HOH540 4.4 38.4 1.0 O D:ILE434 4.5 35.7 1.0 CA D:CYS435 4.5 30.8 1.0 C D:ASP431 4.5 27.6 1.0 CB D:ASP431 4.6 24.9 1.0 O D:HOH575 4.6 46.7 1.0 N D:ASP431 4.6 23.8 1.0 N D:ILE434 4.7 33.0 1.0 CA D:ASP431 4.8 26.3 1.0 CA D:ILE434 4.9 35.0 1.0 N D:CYS437 5.0 28.8 1.0

W.A.Barton, D.Tzvetkova, D.B.Nikolov. Structure of the Angiopoietin-2 Receptor Binding Domain and Identification of Surfaces Involved in TIE2 Recognition. Structure V. 13 825 2005.
ISSN: ISSN 0969-2126
PubMed: 15893672
DOI: 10.1016/J.STR.2005.03.009