Calcium in PDB 2a11: Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis

All present enzymatic activity of Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis:
3.1.26.3;

The structure of Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis, PDB code: 2a11 was solved by D.L.Akey, J.M.Berger, Mycobacterium Tuberculosis Structural Proteomicsproject (Xmtb), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.10
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	72.589, 72.589, 96.013, 90.00, 90.00, 90.00
R / Rfree (%)	25.9 / 28.6

The binding sites of Calcium atom in the Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis (pdb code 2a11). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis, PDB code: 2a11:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1001 b:72.0 occ:1.00 OE2 A:GLU44 2.3 62.5 1.0 O A:HOH1009 2.6 60.2 1.0 OE1 A:GLU123 2.8 41.4 1.0 O A:HOH1008 2.8 48.1 1.0 O A:HOH1010 2.9 67.3 1.0 CD A:GLU44 3.2 56.2 1.0 CG A:GLU44 3.5 43.6 1.0 OD1 A:ASP120 3.5 58.6 1.0 CD A:GLU123 3.9 44.0 1.0 OD1 A:ASP48 4.1 52.5 1.0 OE1 A:GLU44 4.3 57.9 1.0 OE2 A:GLU123 4.4 47.6 1.0 O A:HOH1025 4.5 49.2 1.0 CG A:ASP120 4.5 52.6 1.0 CG A:ASP48 4.7 40.1 1.0 O A:HOH1104 4.7 67.7 1.0 CB A:ASP48 4.8 31.2 1.0 O A:HOH1123 4.9 73.2 1.0 CB A:GLU44 4.9 31.8 1.0 O A:HOH1163 4.9 50.7 1.0 O A:GLU44 4.9 31.6 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Nuclease Domain of Ribonuclase III From Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1002 b:76.6 occ:1.00 O A:HOH1004 2.3 70.6 1.0 O A:HOH1007 2.5 91.5 1.0 O A:HOH1005 2.5 88.8 1.0 O A:HOH1006 2.8 75.6 1.0 O A:HOH1010 3.3 67.3 1.0 O A:HOH1098 4.0 72.8 1.0 OE2 A:GLU44 4.1 62.5 1.0 OD2 A:ASP120 4.5 57.1 1.0 OE1 A:GLU44 4.5 57.9 1.0 CD A:GLU44 4.8 56.2 1.0

D.L.Akey, J.M.Berger. Structure of the Nuclease Domain of Ribonuclease III From M. Tuberculosis at 2.1 A Protein Sci. V. 14 2744 2005.
ISSN: ISSN 0961-8368
PubMed: 16155207
DOI: 10.1110/PS.051665905