Calcium in PDB 2a4e: Crystal Structure of Mouse Cadherin-11 EC1-2

The structure of Crystal Structure of Mouse Cadherin-11 EC1-2, PDB code: 2a4e was solved by S.D.Patel, C.Ciatto, C.P.Chen, F.Bahna, N.Arkus, M.Rajebhosale, T.M.Jessell, B.Honig, S.R.Price, L.Shapiro, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 3.20
Space group	P 62 2 2
Cell size a, b, c (Å), α, β, γ (°)	203.249, 203.249, 42.811, 90.00, 90.00, 120.00
R / Rfree (%)	21.1 / 24.7

The binding sites of Calcium atom in the Crystal Structure of Mouse Cadherin-11 EC1-2 (pdb code 2a4e). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure of Mouse Cadherin-11 EC1-2, PDB code: 2a4e:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Crystal Structure of Mouse Cadherin-11 EC1-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Mouse Cadherin-11 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca301 b:65.4 occ:1.00 O A:SER141 2.2 75.4 1.0 O A:ASN102 2.3 69.7 1.0 OD2 A:ASP132 2.3 76.9 1.0 OD2 A:ASP134 2.3 72.9 1.0 OD1 A:ASN100 2.7 67.3 1.0 OD1 A:ASP187 2.8 83.9 1.0 OD2 A:ASP187 2.8 82.0 1.0 CG A:ASP132 3.0 76.2 1.0 OD1 A:ASP132 3.0 74.3 1.0 CG A:ASP187 3.1 80.8 1.0 CG A:ASP134 3.4 72.5 1.0 C A:ASN102 3.4 69.8 1.0 C A:SER141 3.4 75.8 1.0 CG A:ASN100 3.7 65.9 1.0 CB A:ASP134 3.9 72.0 1.0 CB A:SER141 4.1 75.8 1.0 CA A:SER141 4.2 75.5 1.0 CA A:ASN102 4.2 68.7 1.0 N A:ASN102 4.2 67.5 1.0 ND2 A:ASN100 4.3 68.6 1.0 CB A:ASN102 4.4 68.7 1.0 OD1 A:ASP134 4.4 73.6 1.0 N A:PRO103 4.4 70.9 1.0 CB A:ASP187 4.4 78.5 1.0 CB A:ASP132 4.5 76.3 1.0 CA A:PRO103 4.5 71.9 1.0 N A:ALA142 4.5 76.4 1.0 CD A:PRO104 4.6 74.0 1.0 C A:PRO103 4.7 73.1 1.0 N A:PRO104 4.7 74.2 1.0 N A:ASP134 4.7 72.6 1.0 CA A:ALA142 4.8 76.8 1.0 CB A:ASN100 4.9 64.5 1.0 CA A:ASP134 5.0 72.1 1.0 CA A:ASN100 5.0 64.5 1.0

Calcium binding site 2 out of 3 in the Crystal Structure of Mouse Cadherin-11 EC1-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Mouse Cadherin-11 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca302 b:60.3 occ:1.00 OD1 A:ASP98 2.2 63.6 1.0 O A:ILE99 2.4 64.8 1.0 OD2 A:ASP101 2.4 59.4 1.0 OE2 A:GLU66 2.5 65.4 1.0 OD1 A:ASP134 2.5 73.6 1.0 OE2 A:GLU11 2.9 74.0 1.0 OE1 A:GLU66 3.1 64.5 1.0 CD A:GLU66 3.2 66.0 1.0 OE1 A:GLU11 3.2 74.2 1.0 CG A:ASP98 3.4 66.8 1.0 CD A:GLU11 3.4 74.4 1.0 CG A:ASP101 3.5 62.2 1.0 C A:ILE99 3.5 65.0 1.0 N A:ILE99 3.6 65.6 1.0 NH1 A:ARG65 3.6 67.8 1.0 CG A:ASP134 3.7 72.5 1.0 CA A:CA303 3.9 88.0 1.0 ND2 A:ASN102 3.9 69.6 1.0 OD1 A:ASP101 4.0 60.5 1.0 N A:ASP101 4.1 64.3 1.0 CA A:ILE99 4.2 65.3 1.0 OD2 A:ASP98 4.2 67.4 1.0 CB A:ASP134 4.2 72.0 1.0 CG2 A:ILE99 4.2 63.5 1.0 CA A:ASP134 4.4 72.1 1.0 CG A:ARG65 4.4 68.8 1.0 CB A:ASP98 4.5 67.0 1.0 CA A:ASP98 4.5 66.5 1.0 C A:ASP98 4.5 65.8 1.0 N A:ASN100 4.6 64.8 1.0 CB A:ILE99 4.6 65.5 1.0 CG A:GLU66 4.6 68.1 1.0 OD2 A:ASP134 4.7 72.9 1.0 CB A:ASP101 4.7 64.3 1.0 CA A:ASN100 4.8 64.5 1.0 CA A:ASP101 4.9 64.8 1.0 CG A:GLU11 4.9 74.5 1.0 C A:ASN100 4.9 64.2 1.0 CZ A:ARG65 5.0 67.3 1.0

Calcium binding site 3 out of 3 in the Crystal Structure of Mouse Cadherin-11 EC1-2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of Mouse Cadherin-11 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca303 b:88.0 occ:1.00 OD2 A:ASP64 2.0 71.4 1.0 OE2 A:GLU11 2.2 74.0 1.0 OD1 A:ASP101 2.2 60.5 1.0 OE2 A:GLU12 2.5 76.3 1.0 OE2 A:GLU66 2.5 65.4 1.0 CG A:ASP101 3.1 62.2 1.0 CG A:ASP64 3.2 70.8 1.0 CD A:GLU11 3.3 74.4 1.0 OD2 A:ASP101 3.3 59.4 1.0 CD A:GLU12 3.6 78.2 1.0 CD A:GLU66 3.7 66.0 1.0 CA A:CA302 3.9 60.3 1.0 CG A:GLU11 3.9 74.5 1.0 OD1 A:ASP64 4.0 72.1 1.0 N A:ARG65 4.2 69.4 1.0 CB A:ASP64 4.2 70.2 1.0 CG A:GLU66 4.2 68.1 1.0 OE1 A:GLU12 4.2 79.5 1.0 CA A:ASP64 4.2 70.0 1.0 OE1 A:GLU11 4.3 74.2 1.0 CB A:GLU66 4.3 69.5 1.0 N A:GLU66 4.3 69.8 1.0 CB A:ASP101 4.5 64.3 1.0 C A:ASP64 4.5 69.8 1.0 ND2 A:ASN102 4.5 69.6 1.0 CG A:GLU12 4.5 77.4 1.0 OE1 A:GLU66 4.7 64.5 1.0 CA A:GLU66 5.0 70.1 1.0

S.D.Patel, C.Ciatto, C.P.Chen, F.Bahna, M.Rajebhosale, N.Arkus, I.Schieren, T.M.Jessell, B.Honig, S.R.Price, L.Shapiro. Type II Cadherin Ectodomain Structures: Implications For Classical Cadherin Specificity. Cell(Cambridge,Mass.) V. 124 1255 2006.
ISSN: ISSN 0092-8674
PubMed: 16564015
DOI: 10.1016/J.CELL.2005.12.046