Calcium in PDB 2a5x: Crystal Structure of A Cross-Linked Actin Dimer

The structure of Crystal Structure of A Cross-Linked Actin Dimer, PDB code: 2a5x was solved by D.S.Kudryashov, M.R.Sawaya, H.Adisetiyo, T.Norcross, G.Hegyi, E.Reisler, T.O.Yeates, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	90.00 / 2.49
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	207.377, 54.372, 36.200, 90.00, 98.62, 90.00
R / Rfree (%)	19.4 / 25

The binding sites of Calcium atom in the Crystal Structure of A Cross-Linked Actin Dimer (pdb code 2a5x). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of A Cross-Linked Actin Dimer, PDB code: 2a5x:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of A Cross-Linked Actin Dimer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of A Cross-Linked Actin Dimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca376 b:27.5 occ:1.00 O A:HOH415 2.3 23.7 1.0 O1B A:ANP378 2.3 21.1 1.0 O2G A:ANP378 2.4 25.8 1.0 PB A:ANP378 3.6 21.9 1.0 PG A:ANP378 3.7 25.5 1.0 O A:HOH411 3.9 20.9 1.0 OE1 A:GLN137 4.2 24.1 1.0 O3A A:ANP378 4.2 22.1 1.0 N3B A:ANP378 4.2 23.4 1.0 NZ A:LYS18 4.2 27.1 1.0 O1G A:ANP378 4.3 23.9 1.0 OD1 A:ASP154 4.3 35.0 1.0 O1A A:ANP378 4.4 20.4 1.0 CA A:GLY13 4.5 29.7 1.0 CD A:GLN137 4.5 27.0 1.0 OD2 A:ASP11 4.6 31.0 1.0 PA A:ANP378 4.7 20.6 1.0 OD1 A:ASP11 4.8 31.8 1.0 CG2 A:VAL339 4.8 24.4 1.0 O2B A:ANP378 4.9 20.1 1.0 O3G A:ANP378 4.9 26.0 1.0 NE2 A:GLN137 4.9 26.3 1.0 O2A A:ANP378 5.0 18.0 1.0 OD2 A:ASP154 5.0 32.1 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of A Cross-Linked Actin Dimer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of A Cross-Linked Actin Dimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca377 b:44.6 occ:1.00 O A:HOH384 2.3 38.4 1.0 OE1 A:GLN263 2.4 31.1 1.0 O A:HOH383 2.4 25.7 1.0 OG A:SER265 2.5 25.0 1.0 O A:HOH385 2.7 38.6 1.0 CB A:SER265 3.3 25.5 1.0 CD A:GLN263 3.5 31.0 1.0 NE2 A:GLN263 4.0 32.2 1.0 N A:SER265 4.0 24.8 1.0 CA A:SER265 4.3 25.3 1.0 O A:SER271 4.3 34.8 1.0 O A:MET269 4.5 34.4 1.0 O A:GLU270 4.7 36.7 1.0 CG A:GLN263 4.7 29.2 1.0 CD A:PRO264 4.8 26.2 1.0 N A:PRO264 5.0 26.6 1.0

D.S.Kudryashov, M.R.Sawaya, H.Adisetiyo, T.Norcross, G.Hegyi, E.Reisler, T.O.Yeates. The Crystal Structure of A Cross-Linked Actin Dimer Suggests A Detailed Molecular Interface in F-Actin Proc.Natl.Acad.Sci.Usa V. 102 13105 2005.
ISSN: ISSN 0027-8424
PubMed: 16141336
DOI: 10.1073/PNAS.0506429102