Calcium in PDB 2bpe: Structure of Murine Dectin-1

The structure of Structure of Murine Dectin-1, PDB code: 2bpe was solved by J.Brown, C.A.O'callaghan, A.S.J.Marshall, R.J.C.Gilbert, C.Siebold, S.Gordon, G.D.Brown, E.Y.Jones, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	73.32 / 2.25
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	84.685, 84.685, 117.686, 90.00, 90.00, 120.00
R / Rfree (%)	18.8 / 23.1

The structure of Structure of Murine Dectin-1 also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Calcium atom in the Structure of Murine Dectin-1 (pdb code 2bpe). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of Murine Dectin-1, PDB code: 2bpe:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of Murine Dectin-1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Murine Dectin-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1245 b:35.1 occ:1.00 OD2 A:ASP158 2.2 38.4 1.0 OE1 A:GLU241 2.3 37.8 1.0 O A:LYS156 2.3 34.5 1.0 OE1 A:GLU162 2.4 31.8 1.0 O A:HOH2043 2.4 38.5 1.0 O A:HOH2042 2.5 33.2 1.0 OE2 A:GLU162 2.7 33.8 1.0 CD A:GLU162 2.9 33.0 1.0 OE2 A:GLU241 2.9 36.6 1.0 CD A:GLU241 3.0 36.7 1.0 CG A:ASP158 3.4 36.4 1.0 C A:LYS156 3.5 34.4 1.0 CB A:ASP158 4.1 35.4 1.0 N A:ASP158 4.2 35.2 1.0 CB A:LYS156 4.3 33.9 1.0 CA A:LYS156 4.3 33.9 1.0 O A:HOH2045 4.3 53.0 1.0 N A:LYS156 4.3 32.8 1.0 CG A:GLU162 4.4 31.7 1.0 OD1 A:ASP158 4.4 40.4 1.0 OH A:TYR131 4.4 33.4 1.0 OG A:SER129 4.4 35.7 1.0 CG A:GLU241 4.4 36.3 1.0 N A:ILE157 4.5 34.5 1.0 CA A:ILE157 4.5 34.6 1.0 CG A:LYS156 4.6 35.0 1.0 C A:ILE157 4.7 35.1 1.0 CA A:ASP158 4.8 35.6 1.0 CD1 A:LEU155 4.8 29.1 1.0

Calcium binding site 2 out of 2 in the Structure of Murine Dectin-1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Murine Dectin-1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1245 b:34.6 occ:1.00 OD2 B:ASP158 2.2 38.4 1.0 O B:LYS156 2.4 33.6 1.0 OE1 B:GLU162 2.4 30.4 1.0 OE1 B:GLU241 2.5 36.3 1.0 O B:HOH2035 2.5 32.2 1.0 O B:HOH2044 2.6 42.0 1.0 OE2 B:GLU162 2.7 32.7 1.0 OE2 B:GLU241 2.8 38.1 1.0 CD B:GLU162 2.9 32.1 1.0 CD B:GLU241 3.0 37.0 1.0 CG B:ASP158 3.4 36.8 1.0 C B:LYS156 3.5 34.1 1.0 CB B:ASP158 4.1 35.5 1.0 N B:ASP158 4.2 35.4 1.0 CB B:LYS156 4.3 33.7 1.0 CA B:LYS156 4.3 33.9 1.0 OH B:TYR131 4.4 33.2 1.0 OG B:SER129 4.4 35.0 1.0 CG B:GLU162 4.4 31.4 1.0 OD1 B:ASP158 4.4 42.0 1.0 N B:ILE157 4.5 34.8 1.0 N B:LYS156 4.5 33.2 1.0 CG B:GLU241 4.5 36.1 1.0 CA B:ILE157 4.5 34.6 1.0 O B:HOH2034 4.5 47.2 1.0 C B:ILE157 4.7 35.2 1.0 CA B:ASP158 4.8 35.8 1.0 CD1 B:LEU155 4.9 29.0 1.0 CG B:LYS156 4.9 33.5 1.0

J.Brown, C.A.O'callaghan, A.S.J.Marshall, R.J.C.Gilbert, C.Siebold, S.Gordon, G.D.Brown, E.Y.Jones. Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications For Function. Protein Sci. V. 16 1042 2007.
ISSN: ISSN 0961-8368
PubMed: 17473009
DOI: 10.1110/PS.072791207