Calcium in PDB 2c5d: Structure of A Minimal GAS6-Axl Complex

All present enzymatic activity of Structure of A Minimal GAS6-Axl Complex:
2.7.1.112;

The structure of Structure of A Minimal GAS6-Axl Complex, PDB code: 2c5d was solved by T.Sasaki, P.G.Knyazev, N.J.Clout, Y.Cheburkin, W.Goehring, A.Ullrich, R.Timpl, E.Hohenester, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20 / 3.3
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	292.951, 292.951, 63.951, 90.00, 90.00, 120.00
R / Rfree (%)	24.09 / 26.53

The structure of Structure of A Minimal GAS6-Axl Complex also contains other interesting chemical elements:

Nickel

(Ni)

2 atoms

The binding sites of Calcium atom in the Structure of A Minimal GAS6-Axl Complex (pdb code 2c5d). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of A Minimal GAS6-Axl Complex, PDB code: 2c5d:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of A Minimal GAS6-Axl Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of A Minimal GAS6-Axl Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1677 b:40.5 occ:1.00 O A:GLU331 2.2 37.6 1.0 OD2 A:ASP329 2.3 38.4 1.0 O A:ARG440 2.4 41.4 1.0 OD1 A:ASP329 2.5 39.9 1.0 CG A:ASP329 2.7 39.2 1.0 OD2 A:ASP656 2.8 44.1 1.0 C A:GLU331 3.3 36.8 1.0 CG A:ASP656 3.6 45.9 1.0 C A:ARG440 3.7 41.2 1.0 CB A:GLU331 3.9 42.4 1.0 CA A:GLU331 4.0 38.6 1.0 CB A:ASP656 4.1 46.2 1.0 N A:GLU331 4.1 38.4 1.0 CB A:ASP329 4.3 39.1 1.0 N A:GLY332 4.3 34.5 1.0 O A:ASN438 4.3 39.4 1.0 CA A:LEU441 4.4 42.8 1.0 CE1 A:HIS668 4.4 53.2 1.0 N A:LEU441 4.5 42.4 1.0 CA A:GLY332 4.5 31.7 1.0 OD1 A:ASP656 4.5 46.0 1.0 CG A:GLU331 4.7 49.5 1.0 CA A:ARG440 4.7 39.8 1.0 NE2 A:HIS668 4.8 53.2 1.0 CB A:ARG440 4.8 39.5 1.0 OD2 A:ASP654 4.9 62.5 1.0

Calcium binding site 2 out of 2 in the Structure of A Minimal GAS6-Axl Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of A Minimal GAS6-Axl Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1677 b:46.0 occ:1.00 O B:GLU331 2.3 37.5 1.0 O B:ARG440 2.4 43.2 1.0 OD2 B:ASP329 2.5 39.7 1.0 OD1 B:ASP329 2.7 40.0 1.0 OD2 B:ASP656 2.8 45.3 1.0 CG B:ASP329 2.9 39.2 1.0 C B:GLU331 3.3 37.0 1.0 CG B:ASP656 3.6 46.6 1.0 C B:ARG440 3.6 43.6 1.0 CB B:GLU331 3.9 43.2 1.0 CB B:ASP656 4.0 46.4 1.0 CA B:GLU331 4.0 38.9 1.0 O B:ASN438 4.1 40.4 1.0 N B:GLU331 4.2 38.4 1.0 N B:GLY332 4.3 35.1 1.0 CA B:LEU441 4.4 43.8 1.0 N B:LEU441 4.4 44.5 1.0 CB B:ASP329 4.4 38.4 1.0 CA B:GLY332 4.5 32.7 1.0 OD1 B:ASP656 4.5 47.4 1.0 CE1 B:HIS668 4.5 54.7 1.0 CG B:GLU331 4.6 49.3 1.0 CA B:ARG440 4.6 42.5 1.0 CB B:ARG440 4.7 43.2 1.0 NE2 B:HIS668 4.9 55.8 1.0 OD2 B:ASP654 5.0 61.9 1.0

T.Sasaki, P.G.Knyazev, N.J.Clout, Y.Cheburkin, W.Goehring, A.Ullrich, R.Timpl, E.Hohenester. Structural Basis For GAS6-Axl Signalling. Embo J. V. 25 80 2006.
ISSN: ISSN 0261-4189
PubMed: 16362042
DOI: 10.1038/SJ.EMBOJ.7600912