Calcium in PDB 2dso: Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
Enzymatic activity of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
All present enzymatic activity of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus:
3.1.1.25;
Protein crystallography data
The structure of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus, PDB code: 2dso
was solved by
Y.Tanaka,
Y.Ohki,
K.Morikawa,
M.Yao,
N.Watanabe,
T.Ohta,
I.Tanaka,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
19.99 /
2.10
|
|
Space group
|
P 1 21 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
76.548,
182.432,
81.454,
90.00,
115.58,
90.00
|
|
R / Rfree (%)
|
16.8 /
20.2
|
Calcium Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Calcium atom in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
(pdb code 2dso). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 12 binding sites of Calcium where determined in the
Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus, PDB code: 2dso:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Calcium binding site 1 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 1 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca1001
b:22.8
occ:1.00
|
O
|
A:HOH5034
|
2.1
|
21.5
|
1.0
|
|
OD2
|
A:ASP236
|
2.3
|
28.1
|
1.0
|
|
OD1
|
A:ASN185
|
2.4
|
24.1
|
1.0
|
|
OD1
|
A:ASN138
|
2.4
|
26.2
|
1.0
|
|
OG
|
A:SER237
|
2.4
|
18.1
|
1.0
|
|
OE2
|
A:GLU48
|
2.5
|
38.3
|
1.0
|
|
O
|
A:HOH5104
|
2.5
|
22.9
|
1.0
|
|
CG
|
A:ASN138
|
3.4
|
24.9
|
1.0
|
|
CG
|
A:ASN185
|
3.4
|
23.0
|
1.0
|
|
CG
|
A:ASP236
|
3.6
|
26.1
|
1.0
|
|
CD
|
A:GLU48
|
3.6
|
36.8
|
1.0
|
|
CB
|
A:SER237
|
3.6
|
19.0
|
1.0
|
|
N
|
A:SER237
|
3.7
|
18.6
|
1.0
|
|
ND2
|
A:ASN138
|
3.8
|
23.8
|
1.0
|
|
ND2
|
A:ASN185
|
3.8
|
23.0
|
1.0
|
|
OE1
|
A:GLU48
|
4.0
|
38.0
|
1.0
|
|
CA
|
A:SER237
|
4.0
|
19.3
|
1.0
|
|
OD1
|
A:ASP236
|
4.2
|
29.7
|
1.0
|
|
OD2
|
A:ASP139
|
4.4
|
27.5
|
1.0
|
|
C
|
A:ASP236
|
4.4
|
21.7
|
1.0
|
|
O
|
A:THR283
|
4.5
|
22.5
|
1.0
|
|
O
|
A:ASN138
|
4.6
|
21.3
|
1.0
|
|
CB
|
A:ASP236
|
4.6
|
24.0
|
1.0
|
|
CB
|
A:ASN138
|
4.8
|
22.3
|
1.0
|
|
C
|
A:ASN185
|
4.8
|
21.6
|
1.0
|
|
CB
|
A:ASN185
|
4.8
|
21.3
|
1.0
|
|
CA
|
A:ASP236
|
4.8
|
21.3
|
1.0
|
|
O
|
A:ASN185
|
4.8
|
23.0
|
1.0
|
|
CG
|
A:GLU48
|
4.8
|
33.4
|
1.0
|
|
ND1
|
A:HIS284
|
4.9
|
22.8
|
1.0
|
|
O
|
A:ALA90
|
4.9
|
22.4
|
1.0
|
|
CB
|
A:ASP139
|
4.9
|
22.7
|
1.0
|
|
N
|
A:GLY186
|
5.0
|
20.1
|
1.0
|
|
Calcium binding site 2 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 2 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca1007
b:25.8
occ:0.60
|
O
|
A:SER110
|
2.3
|
27.4
|
1.0
|
|
O
|
A:GLY112
|
2.4
|
21.5
|
1.0
|
|
O
|
A:ASP130
|
2.4
|
31.7
|
1.0
|
|
O
|
A:THR133
|
2.5
|
30.3
|
1.0
|
|
O
|
A:TYR135
|
2.6
|
22.7
|
1.0
|
|
OG1
|
A:THR133
|
2.8
|
34.2
|
1.0
|
|
C
|
A:THR133
|
3.3
|
30.6
|
1.0
|
|
N
|
A:GLY112
|
3.3
|
22.3
|
1.0
|
|
C
|
A:GLY112
|
3.4
|
20.6
|
1.0
|
|
C
|
A:ASP130
|
3.4
|
33.2
|
1.0
|
|
N
|
A:TYR135
|
3.4
|
25.1
|
1.0
|
|
C
|
A:SER110
|
3.5
|
25.8
|
1.0
|
|
C
|
A:TYR135
|
3.5
|
23.9
|
1.0
|
|
CA
|
A:ASP130
|
3.8
|
32.0
|
1.0
|
|
C
|
A:THR111
|
3.8
|
23.7
|
1.0
|
|
C
|
A:ALA134
|
3.8
|
26.8
|
1.0
|
|
CA
|
A:TYR135
|
3.9
|
24.2
|
1.0
|
|
CA
|
A:GLY112
|
3.9
|
20.6
|
1.0
|
|
CB
|
A:THR133
|
3.9
|
31.4
|
1.0
|
|
CA
|
A:THR111
|
4.0
|
24.8
|
1.0
|
|
O
|
A:HOH5063
|
4.0
|
28.1
|
1.0
|
|
N
|
A:ALA134
|
4.1
|
28.1
|
1.0
|
|
CA
|
A:THR133
|
4.1
|
32.0
|
1.0
|
|
O
|
A:GLU129
|
4.1
|
30.4
|
1.0
|
|
N
|
A:THR111
|
4.2
|
24.4
|
1.0
|
|
CA
|
A:ALA134
|
4.2
|
28.3
|
1.0
|
|
N
|
A:THR133
|
4.3
|
33.6
|
1.0
|
|
CB
|
A:TYR135
|
4.3
|
24.0
|
1.0
|
|
O
|
A:ALA134
|
4.4
|
27.0
|
1.0
|
|
N
|
A:GLY113
|
4.5
|
20.3
|
1.0
|
|
O
|
A:THR111
|
4.6
|
24.7
|
1.0
|
|
CA
|
A:SER110
|
4.6
|
27.0
|
1.0
|
|
CB
|
A:ASP130
|
4.6
|
33.1
|
1.0
|
|
N
|
A:LEU131
|
4.6
|
33.6
|
1.0
|
|
N
|
A:CYS136
|
4.8
|
22.1
|
1.0
|
|
N
|
A:ASP130
|
4.8
|
30.6
|
1.0
|
|
CA
|
A:GLY113
|
4.9
|
19.4
|
1.0
|
|
C
|
A:GLU129
|
4.9
|
30.1
|
1.0
|
|
Calcium binding site 3 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 3 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca1002
b:24.6
occ:1.00
|
OD1
|
B:ASN185
|
2.3
|
21.8
|
1.0
|
|
OD1
|
B:ASN138
|
2.4
|
29.3
|
1.0
|
|
O
|
B:HOH1038
|
2.4
|
23.4
|
1.0
|
|
OD1
|
B:ASP236
|
2.5
|
32.2
|
1.0
|
|
OG
|
B:SER237
|
2.5
|
22.9
|
1.0
|
|
OE2
|
B:GLU48
|
2.5
|
38.3
|
1.0
|
|
O
|
B:HOH1011
|
2.5
|
20.9
|
1.0
|
|
O
|
B:HOH1151
|
2.8
|
42.8
|
1.0
|
|
CG
|
B:ASN185
|
3.4
|
22.4
|
1.0
|
|
CG
|
B:ASN138
|
3.4
|
24.7
|
1.0
|
|
CD
|
B:GLU48
|
3.6
|
36.5
|
1.0
|
|
CG
|
B:ASP236
|
3.7
|
30.8
|
1.0
|
|
CB
|
B:SER237
|
3.7
|
20.0
|
1.0
|
|
N
|
B:SER237
|
3.8
|
20.4
|
1.0
|
|
ND2
|
B:ASN138
|
3.9
|
24.6
|
1.0
|
|
ND2
|
B:ASN185
|
3.9
|
21.0
|
1.0
|
|
OE1
|
B:GLU48
|
4.0
|
37.2
|
1.0
|
|
CA
|
B:SER237
|
4.0
|
22.2
|
1.0
|
|
OD2
|
B:ASP236
|
4.4
|
35.1
|
1.0
|
|
C
|
B:ASP236
|
4.4
|
21.1
|
1.0
|
|
O
|
B:HOH1073
|
4.4
|
37.1
|
1.0
|
|
OD2
|
B:ASP139
|
4.5
|
27.1
|
1.0
|
|
O
|
B:ASN185
|
4.5
|
20.3
|
1.0
|
|
O
|
B:ASN138
|
4.6
|
22.2
|
1.0
|
|
O
|
B:THR283
|
4.6
|
21.2
|
1.0
|
|
C
|
B:ASN185
|
4.6
|
20.4
|
1.0
|
|
CB
|
B:ASN138
|
4.7
|
24.0
|
1.0
|
|
CB
|
B:ASN185
|
4.7
|
19.2
|
1.0
|
|
CB
|
B:ASP236
|
4.7
|
25.6
|
1.0
|
|
O
|
B:ALA90
|
4.8
|
24.0
|
1.0
|
|
CA
|
B:ASP236
|
4.8
|
21.5
|
1.0
|
|
CG
|
B:GLU48
|
4.9
|
33.2
|
1.0
|
|
CB
|
B:ASP139
|
5.0
|
24.5
|
1.0
|
|
N
|
B:GLY186
|
5.0
|
19.7
|
1.0
|
|
CA
|
B:ASN185
|
5.0
|
19.9
|
1.0
|
|
Calcium binding site 4 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 4 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca1008
b:26.1
occ:0.60
|
O
|
B:SER110
|
2.3
|
24.4
|
1.0
|
|
OG1
|
B:THR133
|
2.5
|
26.7
|
1.0
|
|
O
|
B:ASP130
|
2.5
|
27.3
|
1.0
|
|
O
|
B:GLY112
|
2.5
|
20.1
|
1.0
|
|
O
|
B:TYR135
|
2.5
|
25.9
|
1.0
|
|
O
|
B:THR133
|
2.5
|
27.2
|
1.0
|
|
C
|
B:THR133
|
3.2
|
26.5
|
1.0
|
|
N
|
B:TYR135
|
3.3
|
25.9
|
1.0
|
|
N
|
B:GLY112
|
3.3
|
22.5
|
1.0
|
|
C
|
B:ASP130
|
3.5
|
28.3
|
1.0
|
|
C
|
B:SER110
|
3.5
|
24.4
|
1.0
|
|
C
|
B:TYR135
|
3.5
|
27.0
|
1.0
|
|
C
|
B:GLY112
|
3.5
|
22.2
|
1.0
|
|
CB
|
B:THR133
|
3.6
|
27.8
|
1.0
|
|
C
|
B:ALA134
|
3.8
|
25.3
|
1.0
|
|
CA
|
B:TYR135
|
3.8
|
27.1
|
1.0
|
|
CA
|
B:ASP130
|
3.8
|
28.2
|
1.0
|
|
C
|
B:THR111
|
3.8
|
23.9
|
1.0
|
|
CA
|
B:THR133
|
3.9
|
28.0
|
1.0
|
|
N
|
B:ALA134
|
3.9
|
26.3
|
1.0
|
|
CA
|
B:THR111
|
3.9
|
24.4
|
1.0
|
|
O
|
B:GLU129
|
4.0
|
31.6
|
1.0
|
|
CA
|
B:GLY112
|
4.0
|
21.6
|
1.0
|
|
N
|
B:THR111
|
4.1
|
23.4
|
1.0
|
|
CA
|
B:ALA134
|
4.1
|
25.7
|
1.0
|
|
N
|
B:THR133
|
4.2
|
28.5
|
1.0
|
|
O
|
B:HOH1024
|
4.2
|
24.0
|
1.0
|
|
CB
|
B:TYR135
|
4.2
|
27.0
|
1.0
|
|
O
|
B:ALA134
|
4.4
|
26.7
|
1.0
|
|
CA
|
B:SER110
|
4.6
|
25.9
|
1.0
|
|
N
|
B:GLY113
|
4.7
|
21.1
|
1.0
|
|
N
|
B:LEU131
|
4.7
|
29.1
|
1.0
|
|
N
|
B:CYS136
|
4.7
|
26.4
|
1.0
|
|
CB
|
B:ASP130
|
4.7
|
28.9
|
1.0
|
|
O
|
B:THR111
|
4.7
|
24.1
|
1.0
|
|
CG2
|
B:THR133
|
4.8
|
26.9
|
1.0
|
|
N
|
B:ASP130
|
4.8
|
28.9
|
1.0
|
|
C
|
B:GLU129
|
4.8
|
29.9
|
1.0
|
|
Calcium binding site 5 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 5 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca1003
b:22.3
occ:1.00
|
O
|
C:HOH1040
|
2.3
|
26.8
|
1.0
|
|
OD1
|
C:ASN185
|
2.3
|
23.4
|
1.0
|
|
O
|
C:HOH1037
|
2.3
|
23.2
|
1.0
|
|
OD2
|
C:ASP236
|
2.4
|
31.0
|
1.0
|
|
OD1
|
C:ASN138
|
2.5
|
28.9
|
1.0
|
|
OE2
|
C:GLU48
|
2.5
|
34.4
|
1.0
|
|
O
|
C:HOH1133
|
2.5
|
41.6
|
1.0
|
|
OG
|
C:SER237
|
2.6
|
25.1
|
1.0
|
|
CG
|
C:ASN185
|
3.4
|
21.8
|
1.0
|
|
CG
|
C:ASN138
|
3.4
|
29.0
|
1.0
|
|
CG
|
C:ASP236
|
3.6
|
31.5
|
1.0
|
|
CD
|
C:GLU48
|
3.6
|
35.6
|
1.0
|
|
ND2
|
C:ASN138
|
3.7
|
27.9
|
1.0
|
|
ND2
|
C:ASN185
|
3.8
|
20.1
|
1.0
|
|
N
|
C:SER237
|
3.8
|
22.7
|
1.0
|
|
CB
|
C:SER237
|
3.8
|
25.3
|
1.0
|
|
OE1
|
C:GLU48
|
4.0
|
33.6
|
1.0
|
|
CA
|
C:SER237
|
4.1
|
24.0
|
1.0
|
|
OD1
|
C:ASP236
|
4.2
|
36.4
|
1.0
|
|
OD2
|
C:ASP139
|
4.4
|
25.6
|
1.0
|
|
C
|
C:ASP236
|
4.4
|
23.9
|
1.0
|
|
O
|
C:ASN138
|
4.5
|
20.8
|
1.0
|
|
O
|
C:ASN185
|
4.6
|
20.1
|
1.0
|
|
C
|
C:ASN185
|
4.7
|
19.5
|
1.0
|
|
O
|
C:THR283
|
4.7
|
22.2
|
1.0
|
|
CB
|
C:ASN185
|
4.7
|
19.5
|
1.0
|
|
CB
|
C:ASP236
|
4.7
|
28.4
|
1.0
|
|
CB
|
C:ASN138
|
4.8
|
23.7
|
1.0
|
|
CA
|
C:ASP236
|
4.8
|
23.9
|
1.0
|
|
O
|
C:ALA90
|
4.8
|
27.9
|
1.0
|
|
CB
|
C:ASP139
|
4.9
|
22.3
|
1.0
|
|
CG
|
C:GLU48
|
4.9
|
33.6
|
1.0
|
|
N
|
C:GLY186
|
5.0
|
18.2
|
1.0
|
|
Calcium binding site 6 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 6 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca1009
b:30.2
occ:0.60
|
O
|
C:HOH1120
|
2.1
|
38.7
|
1.0
|
|
O
|
C:SER110
|
2.2
|
29.4
|
1.0
|
|
O
|
C:THR133
|
2.5
|
42.1
|
1.0
|
|
O
|
C:TYR135
|
2.5
|
30.4
|
1.0
|
|
O
|
C:ASP130
|
2.5
|
42.3
|
1.0
|
|
O
|
C:GLY112
|
2.6
|
23.2
|
1.0
|
|
C
|
C:SER110
|
3.3
|
30.6
|
1.0
|
|
N
|
C:GLY112
|
3.3
|
28.8
|
1.0
|
|
C
|
C:THR133
|
3.4
|
41.3
|
1.0
|
|
N
|
C:TYR135
|
3.4
|
30.5
|
1.0
|
|
C
|
C:TYR135
|
3.5
|
29.9
|
1.0
|
|
C
|
C:GLY112
|
3.5
|
25.3
|
1.0
|
|
C
|
C:ASP130
|
3.6
|
44.5
|
1.0
|
|
C
|
C:THR111
|
3.7
|
30.6
|
1.0
|
|
C
|
C:ALA134
|
3.7
|
32.1
|
1.0
|
|
CA
|
C:THR111
|
3.8
|
31.7
|
1.0
|
|
CA
|
C:TYR135
|
3.9
|
30.4
|
1.0
|
|
OG1
|
C:THR133
|
3.9
|
50.0
|
1.0
|
|
N
|
C:THR111
|
4.0
|
30.7
|
1.0
|
|
CA
|
C:GLY112
|
4.0
|
25.8
|
1.0
|
|
CA
|
C:ASP130
|
4.0
|
43.5
|
1.0
|
|
N
|
C:ALA134
|
4.0
|
36.6
|
1.0
|
|
CA
|
C:ALA134
|
4.1
|
34.3
|
1.0
|
|
O
|
C:GLU129
|
4.1
|
42.6
|
1.0
|
|
O
|
C:ALA134
|
4.2
|
31.8
|
1.0
|
|
CA
|
C:THR133
|
4.3
|
45.0
|
1.0
|
|
CA
|
C:SER110
|
4.4
|
32.3
|
1.0
|
|
O
|
C:THR111
|
4.5
|
31.9
|
1.0
|
|
N
|
C:THR133
|
4.5
|
47.0
|
1.0
|
|
CB
|
C:TYR135
|
4.6
|
29.7
|
1.0
|
|
CB
|
C:THR133
|
4.6
|
46.9
|
1.0
|
|
N
|
C:GLY113
|
4.7
|
24.9
|
1.0
|
|
N
|
C:CYS136
|
4.7
|
28.6
|
1.0
|
|
N
|
C:LEU131
|
4.8
|
46.0
|
1.0
|
|
CB
|
C:ASP130
|
4.9
|
44.9
|
1.0
|
|
C
|
C:GLU129
|
5.0
|
42.6
|
1.0
|
|
N
|
C:ASP130
|
5.0
|
41.8
|
1.0
|
|
Calcium binding site 7 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 7 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca1004
b:22.1
occ:1.00
|
O
|
D:HOH5018
|
2.2
|
19.9
|
1.0
|
|
OD1
|
D:ASN138
|
2.3
|
23.9
|
1.0
|
|
OD1
|
D:ASN185
|
2.4
|
21.6
|
1.0
|
|
OE2
|
D:GLU48
|
2.4
|
34.1
|
1.0
|
|
OD1
|
D:ASP236
|
2.4
|
28.5
|
1.0
|
|
OG
|
D:SER237
|
2.5
|
22.1
|
1.0
|
|
O
|
D:HOH5084
|
2.5
|
38.4
|
1.0
|
|
O
|
D:HOH5012
|
2.6
|
23.3
|
1.0
|
|
CG
|
D:ASN138
|
3.4
|
22.9
|
1.0
|
|
CG
|
D:ASN185
|
3.5
|
21.8
|
1.0
|
|
CD
|
D:GLU48
|
3.5
|
31.7
|
1.0
|
|
CG
|
D:ASP236
|
3.6
|
27.4
|
1.0
|
|
CB
|
D:SER237
|
3.7
|
18.1
|
1.0
|
|
N
|
D:SER237
|
3.8
|
17.2
|
1.0
|
|
ND2
|
D:ASN138
|
3.8
|
20.9
|
1.0
|
|
ND2
|
D:ASN185
|
3.9
|
20.0
|
1.0
|
|
OE1
|
D:GLU48
|
3.9
|
31.3
|
1.0
|
|
CA
|
D:SER237
|
4.0
|
18.9
|
1.0
|
|
OD2
|
D:ASP236
|
4.3
|
30.3
|
1.0
|
|
OD2
|
D:ASP139
|
4.3
|
22.6
|
1.0
|
|
O
|
D:HOH5087
|
4.4
|
38.6
|
1.0
|
|
C
|
D:ASP236
|
4.5
|
20.1
|
1.0
|
|
O
|
D:ASN138
|
4.6
|
17.3
|
1.0
|
|
O
|
D:THR283
|
4.6
|
19.4
|
1.0
|
|
O
|
D:ASN185
|
4.6
|
20.4
|
1.0
|
|
C
|
D:ASN185
|
4.7
|
20.4
|
1.0
|
|
CB
|
D:ASN138
|
4.7
|
20.9
|
1.0
|
|
CB
|
D:ASP236
|
4.8
|
23.7
|
1.0
|
|
CB
|
D:ASN185
|
4.8
|
18.9
|
1.0
|
|
CG
|
D:GLU48
|
4.8
|
28.7
|
1.0
|
|
O
|
D:ALA90
|
4.8
|
21.1
|
1.0
|
|
ND1
|
D:HIS284
|
4.9
|
18.2
|
1.0
|
|
CA
|
D:ASP236
|
4.9
|
19.8
|
1.0
|
|
CB
|
D:ASP139
|
4.9
|
20.0
|
1.0
|
|
N
|
D:GLY186
|
5.0
|
18.7
|
1.0
|
|
Calcium binding site 8 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 8 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca1010
b:24.5
occ:0.60
|
O
|
D:SER110
|
2.3
|
24.0
|
1.0
|
|
O
|
D:GLY112
|
2.4
|
20.5
|
1.0
|
|
O
|
D:ASP130
|
2.5
|
22.6
|
1.0
|
|
O
|
D:TYR135
|
2.5
|
25.3
|
1.0
|
|
OG1
|
D:THR133
|
2.5
|
21.0
|
1.0
|
|
O
|
D:THR133
|
2.6
|
23.1
|
1.0
|
|
N
|
D:GLY112
|
3.3
|
23.2
|
1.0
|
|
C
|
D:THR133
|
3.3
|
23.0
|
1.0
|
|
C
|
D:SER110
|
3.4
|
23.7
|
1.0
|
|
C
|
D:ASP130
|
3.4
|
23.6
|
1.0
|
|
C
|
D:GLY112
|
3.4
|
22.2
|
1.0
|
|
N
|
D:TYR135
|
3.5
|
23.6
|
1.0
|
|
C
|
D:TYR135
|
3.5
|
23.4
|
1.0
|
|
CA
|
D:ASP130
|
3.7
|
24.3
|
1.0
|
|
CB
|
D:THR133
|
3.7
|
24.0
|
1.0
|
|
C
|
D:THR111
|
3.7
|
23.7
|
1.0
|
|
CA
|
D:TYR135
|
3.8
|
23.8
|
1.0
|
|
O
|
D:HOH5046
|
3.9
|
25.8
|
1.0
|
|
CA
|
D:THR111
|
3.9
|
24.0
|
1.0
|
|
C
|
D:ALA134
|
3.9
|
24.2
|
1.0
|
|
CA
|
D:GLY112
|
3.9
|
22.9
|
1.0
|
|
CA
|
D:THR133
|
3.9
|
22.6
|
1.0
|
|
O
|
D:GLU129
|
3.9
|
25.4
|
1.0
|
|
N
|
D:THR111
|
4.1
|
23.2
|
1.0
|
|
N
|
D:ALA134
|
4.1
|
23.6
|
1.0
|
|
N
|
D:THR133
|
4.2
|
23.4
|
1.0
|
|
CB
|
D:TYR135
|
4.3
|
22.8
|
1.0
|
|
CA
|
D:ALA134
|
4.4
|
24.5
|
1.0
|
|
O
|
D:ALA134
|
4.5
|
23.2
|
1.0
|
|
CA
|
D:SER110
|
4.5
|
25.9
|
1.0
|
|
O
|
D:THR111
|
4.5
|
22.1
|
1.0
|
|
N
|
D:GLY113
|
4.6
|
21.3
|
1.0
|
|
N
|
D:LEU131
|
4.6
|
23.1
|
1.0
|
|
CB
|
D:ASP130
|
4.7
|
25.3
|
1.0
|
|
N
|
D:CYS136
|
4.7
|
22.5
|
1.0
|
|
N
|
D:ASP130
|
4.7
|
24.1
|
1.0
|
|
C
|
D:GLU129
|
4.8
|
24.6
|
1.0
|
|
CG2
|
D:THR133
|
4.9
|
23.2
|
1.0
|
|
CA
|
D:GLY113
|
5.0
|
18.9
|
1.0
|
|
Calcium binding site 9 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 9 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 9 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca1005
b:22.4
occ:1.00
|
O
|
E:HOH1175
|
2.2
|
23.5
|
1.0
|
|
O
|
E:HOH1072
|
2.3
|
22.5
|
1.0
|
|
OD1
|
E:ASP236
|
2.3
|
28.2
|
1.0
|
|
OD1
|
E:ASN185
|
2.4
|
23.5
|
1.0
|
|
OD1
|
E:ASN138
|
2.4
|
25.6
|
1.0
|
|
OG
|
E:SER237
|
2.5
|
19.8
|
1.0
|
|
OE2
|
E:GLU48
|
2.5
|
30.9
|
1.0
|
|
CG
|
E:ASN138
|
3.4
|
21.7
|
1.0
|
|
CG
|
E:ASN185
|
3.5
|
20.9
|
1.0
|
|
CD
|
E:GLU48
|
3.6
|
33.1
|
1.0
|
|
CG
|
E:ASP236
|
3.6
|
26.4
|
1.0
|
|
CB
|
E:SER237
|
3.7
|
18.2
|
1.0
|
|
ND2
|
E:ASN138
|
3.7
|
23.4
|
1.0
|
|
N
|
E:SER237
|
3.7
|
17.7
|
1.0
|
|
ND2
|
E:ASN185
|
3.9
|
20.1
|
1.0
|
|
OE1
|
E:GLU48
|
3.9
|
33.2
|
1.0
|
|
CA
|
E:SER237
|
4.0
|
17.7
|
1.0
|
|
O
|
E:HOH1141
|
4.0
|
37.6
|
1.0
|
|
OD2
|
E:ASP236
|
4.3
|
31.6
|
1.0
|
|
OD2
|
E:ASP139
|
4.4
|
21.1
|
1.0
|
|
C
|
E:ASP236
|
4.4
|
19.2
|
1.0
|
|
O
|
E:ASN138
|
4.6
|
20.1
|
1.0
|
|
O
|
E:THR283
|
4.6
|
20.9
|
1.0
|
|
CB
|
E:ASP236
|
4.6
|
23.6
|
1.0
|
|
O
|
E:ASN185
|
4.7
|
18.2
|
1.0
|
|
C
|
E:ASN185
|
4.7
|
18.7
|
1.0
|
|
CB
|
E:ASN138
|
4.7
|
19.2
|
1.0
|
|
O
|
E:ALA90
|
4.8
|
21.7
|
1.0
|
|
CB
|
E:ASN185
|
4.8
|
19.3
|
1.0
|
|
CA
|
E:ASP236
|
4.8
|
19.6
|
1.0
|
|
O
|
E:HOH1130
|
4.8
|
34.3
|
1.0
|
|
CG
|
E:GLU48
|
4.9
|
30.1
|
1.0
|
|
N
|
E:GLY186
|
5.0
|
17.9
|
1.0
|
|
CB
|
E:ASP139
|
5.0
|
19.6
|
1.0
|
|
Calcium binding site 10 out
of 12 in 2dso
Go back to
Calcium Binding Sites List in 2dso
Calcium binding site 10 out
of 12 in the Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 10 of Crystal Structure of D138N Mutant of DRP35, A 35KDA Drug Responsive Protein From Staphylococcus Aureus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca1011
b:25.8
occ:0.60
|
O
|
E:SER110
|
2.2
|
26.4
|
1.0
|
|
O
|
E:ASP130
|
2.5
|
32.4
|
1.0
|
|
O
|
E:GLY112
|
2.5
|
19.4
|
1.0
|
|
O
|
E:THR133
|
2.5
|
32.6
|
1.0
|
|
O
|
E:TYR135
|
2.5
|
26.8
|
1.0
|
|
OG1
|
E:THR133
|
2.7
|
35.3
|
1.0
|
|
C
|
E:THR133
|
3.2
|
33.1
|
1.0
|
|
N
|
E:GLY112
|
3.3
|
20.7
|
1.0
|
|
C
|
E:SER110
|
3.4
|
26.2
|
1.0
|
|
C
|
E:ASP130
|
3.5
|
33.5
|
1.0
|
|
N
|
E:TYR135
|
3.5
|
26.9
|
1.0
|
|
C
|
E:GLY112
|
3.5
|
19.0
|
1.0
|
|
C
|
E:TYR135
|
3.5
|
27.1
|
1.0
|
|
C
|
E:THR111
|
3.8
|
23.1
|
1.0
|
|
CA
|
E:ASP130
|
3.8
|
33.7
|
1.0
|
|
C
|
E:ALA134
|
3.8
|
28.1
|
1.0
|
|
CB
|
E:THR133
|
3.8
|
35.1
|
1.0
|
|
CA
|
E:THR111
|
3.9
|
23.4
|
1.0
|
|
CA
|
E:TYR135
|
3.9
|
26.0
|
1.0
|
|
CA
|
E:GLY112
|
4.0
|
18.4
|
1.0
|
|
CA
|
E:THR133
|
4.0
|
34.1
|
1.0
|
|
O
|
E:HOH1150
|
4.0
|
36.8
|
1.0
|
|
N
|
E:ALA134
|
4.0
|
30.6
|
1.0
|
|
O
|
E:GLU129
|
4.1
|
32.9
|
1.0
|
|
N
|
E:THR111
|
4.1
|
25.6
|
1.0
|
|
CA
|
E:ALA134
|
4.2
|
29.7
|
1.0
|
|
N
|
E:THR133
|
4.3
|
35.5
|
1.0
|
|
O
|
E:ALA134
|
4.4
|
30.0
|
1.0
|
|
CB
|
E:TYR135
|
4.4
|
25.9
|
1.0
|
|
CA
|
E:SER110
|
4.5
|
27.4
|
1.0
|
|
O
|
E:THR111
|
4.6
|
21.9
|
1.0
|
|
N
|
E:GLY113
|
4.6
|
19.3
|
1.0
|
|
CB
|
E:ASP130
|
4.6
|
34.7
|
1.0
|
|
N
|
E:LEU131
|
4.7
|
35.1
|
1.0
|
|
N
|
E:CYS136
|
4.8
|
25.1
|
1.0
|
|
N
|
E:ASP130
|
4.8
|
31.7
|
1.0
|
|
C
|
E:GLU129
|
4.9
|
31.8
|
1.0
|
|
CA
|
E:GLY113
|
4.9
|
17.2
|
1.0
|
|
Reference:
Y.Tanaka,
K.Morikawa,
Y.Ohki,
M.Yao,
K.Tsumoto,
N.Watanabe,
T.Ohta,
I.Tanaka.
Structural and Mutational Analyses of DRP35 From Staphylococcus Aureus: A Possible Mechanism For Its Lactonase Activity J.Biol.Chem. V. 282 5770 2007.
ISSN: ISSN 0021-9258
PubMed: 17166853
DOI: 10.1074/JBC.M607340200
Page generated: Sat Dec 12 03:35:21 2020
|
