Calcium in PDB 2f3z: Calmodulin/Iq-Aa Domain Complex

The structure of Calmodulin/Iq-Aa Domain Complex, PDB code: 2f3z was solved by J.L.Fallon, F.A.Quiocho, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	21.20 / 1.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	86.260, 31.370, 64.110, 90.00, 115.89, 90.00
R / Rfree (%)	21.9 / 27.2

The binding sites of Calcium atom in the Calmodulin/Iq-Aa Domain Complex (pdb code 2f3z). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Calmodulin/Iq-Aa Domain Complex, PDB code: 2f3z:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Calmodulin/Iq-Aa Domain Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Calmodulin/Iq-Aa Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca165 b:16.7 occ:1.00 OD2 A:ASP131 2.3 21.9 1.0 O A:HOH185 2.3 19.4 1.0 O A:GLN135 2.3 19.2 1.0 OD1 A:ASP129 2.4 17.4 1.0 OD2 A:ASP133 2.4 18.1 1.0 OE2 A:GLU140 2.4 17.4 1.0 OE1 A:GLU140 2.6 16.5 1.0 CD A:GLU140 2.9 17.2 1.0 CG A:ASP131 3.2 21.7 1.0 CG A:ASP133 3.3 21.5 1.0 CG A:ASP129 3.5 18.2 1.0 C A:GLN135 3.5 19.4 1.0 OD1 A:ASP131 3.6 23.7 1.0 OD1 A:ASP133 3.7 17.8 1.0 N A:ASP133 4.1 20.9 1.0 OD2 A:ASP129 4.3 21.0 1.0 N A:GLN135 4.3 18.5 1.0 CA A:ASP129 4.3 19.4 1.0 N A:ASP131 4.3 18.6 1.0 CB A:ASP129 4.3 20.0 1.0 CG A:GLU140 4.4 17.2 1.0 N A:VAL136 4.4 14.7 1.0 CA A:VAL136 4.4 15.7 1.0 CA A:GLN135 4.5 20.6 1.0 CB A:ASP133 4.5 19.0 1.0 N A:GLY132 4.5 18.5 1.0 CB A:ASP131 4.5 19.5 1.0 N A:ASN137 4.5 16.1 1.0 C A:ASP129 4.5 20.1 1.0 CA A:ASP131 4.7 19.8 1.0 N A:ILE130 4.7 20.0 1.0 CA A:ASP133 4.7 19.9 1.0 CG A:GLN135 4.8 27.2 1.0 C A:ASP131 4.8 20.6 1.0 N A:GLY134 4.9 18.1 1.0 C A:VAL136 4.9 15.0 1.0 ND2 A:ASN137 5.0 24.0 1.0

Calcium binding site 2 out of 4 in the Calmodulin/Iq-Aa Domain Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Calmodulin/Iq-Aa Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca166 b:13.5 occ:1.00 O A:TYR99 2.2 16.3 1.0 OD2 A:ASP93 2.3 15.9 1.0 OD1 A:ASP95 2.3 18.4 1.0 O A:HOH173 2.4 15.3 1.0 OD1 A:ASN97 2.4 15.0 1.0 OE2 A:GLU104 2.5 12.6 1.0 OE1 A:GLU104 2.5 15.6 1.0 CD A:GLU104 2.8 11.9 1.0 CG A:ASP95 3.3 17.5 1.0 CG A:ASN97 3.4 17.7 1.0 C A:TYR99 3.4 16.2 1.0 CG A:ASP93 3.5 16.0 1.0 OD2 A:ASP95 3.6 21.1 1.0 ND2 A:ASN97 4.0 14.1 1.0 N A:TYR99 4.1 15.2 1.0 CA A:ASP93 4.2 16.2 1.0 N A:ASN97 4.2 17.4 1.0 CA A:TYR99 4.3 16.1 1.0 OD1 A:ASP93 4.3 15.7 1.0 CG A:GLU104 4.3 13.7 1.0 CB A:ASP93 4.4 16.0 1.0 N A:ASP95 4.4 16.8 1.0 N A:ILE100 4.4 14.0 1.0 CB A:ASN97 4.4 15.1 1.0 CA A:ILE100 4.4 12.4 1.0 O A:HOH179 4.5 17.1 1.0 C A:ASP93 4.5 16.4 1.0 CB A:ASP95 4.5 16.9 1.0 N A:SER101 4.6 13.3 1.0 CB A:TYR99 4.7 15.8 1.0 N A:GLY96 4.7 17.7 1.0 CA A:ASN97 4.7 17.9 1.0 N A:LYS94 4.8 17.1 1.0 CA A:ASP95 4.8 16.3 1.0 N A:GLY98 4.8 16.3 1.0 O A:HOH209 4.8 23.4 1.0 C A:ASP95 4.9 17.4 1.0 C A:ILE100 5.0 12.4 1.0 C A:ASN97 5.0 17.6 1.0 O A:ASP93 5.0 16.9 1.0

Calcium binding site 3 out of 4 in the Calmodulin/Iq-Aa Domain Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Calmodulin/Iq-Aa Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca167 b:19.6 occ:1.00 OD1 A:ASP56 2.2 19.8 1.0 O A:HOH190 2.3 25.4 1.0 O A:HOH188 2.4 22.8 1.0 OD1 A:ASN60 2.4 23.8 1.0 OE1 A:GLU67 2.5 19.1 1.0 O A:THR62 2.5 21.3 1.0 OE2 A:GLU67 2.5 18.9 1.0 OD1 A:ASP58 2.6 22.9 1.0 CD A:GLU67 2.8 19.4 1.0 CG A:ASN60 3.3 26.4 1.0 CG A:ASP56 3.3 21.3 1.0 CG A:ASP58 3.5 27.0 1.0 C A:THR62 3.6 18.9 1.0 ND2 A:ASN60 3.6 28.0 1.0 OD2 A:ASP58 3.8 26.1 1.0 OD2 A:ASP56 4.2 23.9 1.0 CB A:ASP56 4.2 20.9 1.0 CA A:ASP56 4.2 21.4 1.0 N A:ASN60 4.3 25.5 1.0 CG A:GLU67 4.3 18.5 1.0 N A:THR62 4.4 20.2 1.0 CA A:ILE63 4.4 16.3 1.0 N A:ILE63 4.4 18.3 1.0 OG1 A:THR62 4.4 19.1 1.0 N A:ASP64 4.5 18.7 1.0 CB A:ASN60 4.5 25.0 1.0 OD2 A:ASP64 4.5 25.1 1.0 N A:ASP58 4.5 27.3 1.0 CA A:THR62 4.6 19.5 1.0 C A:ASP56 4.6 22.9 1.0 O A:HOH228 4.7 34.8 1.0 CG A:ASP64 4.8 20.6 1.0 CB A:ASP58 4.8 26.6 1.0 N A:ALA57 4.8 23.8 1.0 CA A:ASN60 4.8 25.1 1.0 N A:GLY59 4.8 27.9 1.0 C A:ILE63 4.9 17.6 1.0 CA A:ASP58 5.0 27.5 1.0

Calcium binding site 4 out of 4 in the Calmodulin/Iq-Aa Domain Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Calmodulin/Iq-Aa Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca168 b:19.3 occ:1.00 OD2 A:ASP20 2.2 22.4 1.0 O A:THR26 2.3 21.2 1.0 OD1 A:ASP24 2.3 24.2 1.0 OD2 A:ASP22 2.4 24.5 1.0 O A:HOH199 2.4 25.6 1.0 OE1 A:GLU31 2.5 18.0 1.0 OE2 A:GLU31 2.6 19.9 1.0 CD A:GLU31 2.8 20.8 1.0 CG A:ASP24 3.3 28.8 1.0 CG A:ASP20 3.3 22.6 1.0 CG A:ASP22 3.3 28.7 1.0 C A:THR26 3.5 20.0 1.0 OD1 A:ASP22 3.7 27.5 1.0 OD2 A:ASP24 4.0 28.7 1.0 CA A:ASP20 4.1 22.1 1.0 OG1 A:THR26 4.1 27.1 1.0 N A:THR26 4.1 22.2 1.0 N A:ASP24 4.1 27.7 1.0 OD1 A:ASP20 4.2 24.1 1.0 CB A:ASP20 4.2 22.1 1.0 CB A:ASP24 4.2 27.2 1.0 CG A:GLU31 4.3 18.4 1.0 CA A:THR26 4.4 21.0 1.0 N A:ILE27 4.5 15.7 1.0 C A:ASP20 4.5 25.0 1.0 CA A:ILE27 4.5 15.1 1.0 N A:ASP22 4.5 29.8 1.0 CA A:ASP24 4.6 26.8 1.0 CB A:ASP22 4.7 28.4 1.0 N A:GLY23 4.7 30.2 1.0 N A:LYS21 4.8 26.1 1.0 N A:GLY25 4.8 23.4 1.0 O A:HOH261 4.9 27.3 1.0 CG2 A:THR28 4.9 16.7 1.0 CB A:THR26 4.9 24.7 1.0 C A:ASP24 4.9 26.7 1.0 C A:ASP22 4.9 31.5 1.0 CA A:ASP22 4.9 29.9 1.0 N A:THR28 4.9 17.1 1.0 O A:HOH297 5.0 33.0 1.0

J.L.Fallon, D.B.Halling, S.L.Hamilton, F.A.Quiocho. Structure of Calmodulin Bound to the Hydrophobic Iq Domain of the Cardiac Ca(V)1.2 Calcium Channel. Structure V. 13 1881 2005.
ISSN: ISSN 0969-2126
PubMed: 16338416
DOI: 10.1016/J.STR.2005.09.021