Calcium in PDB 2fws: First CA2+ Binding Domain of the Na,Ca-Exchanger (NCX1)

The binding sites of Calcium atom in the First CA2+ Binding Domain of the Na,Ca-Exchanger (NCX1) (pdb code 2fws). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the First CA2+ Binding Domain of the Na,Ca-Exchanger (NCX1), PDB code: 2fws:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the First CA2+ Binding Domain of the Na,Ca-Exchanger (NCX1)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of First CA2+ Binding Domain of the Na,Ca-Exchanger (NCX1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca600 b:43.4 occ:1.00 OD1 A:ASP498 1.7 51.2 1.0 OE1 A:GLU385 1.7 11.1 1.0 OD1 A:ASP448 1.8 73.2 1.0 OE1 A:GLU451 1.8 3.3 1.0 HA A:ASP448 2.8 71.5 1.0 CG A:ASP498 2.9 20.1 1.0 CD A:GLU385 2.9 2.3 1.0 CD A:GLU451 3.0 14.2 1.0 OD2 A:ASP500 3.0 63.4 1.0 CG A:ASP448 3.1 43.3 1.0 HB2 A:ASP500 3.4 71.4 1.0 H A:ILE449 3.5 73.0 1.0 O A:ASP447 3.5 32.2 1.0 HB2 A:ASP498 3.5 40.4 1.0 OE2 A:GLU385 3.5 63.3 1.0 CB A:ASP498 3.7 22.2 1.0 HA A:ASP498 3.7 3.0 1.0 CA A:ASP448 3.7 25.4 1.0 HB2 A:GLU451 3.7 14.1 1.0 O A:ILE449 3.8 62.4 1.0 OE2 A:GLU451 3.8 13.3 1.0 OD2 A:ASP498 3.9 2.2 1.0 CB A:ASP448 3.9 43.0 1.0 OD2 A:ASP448 3.9 23.2 1.0 CG A:ASP500 3.9 30.3 1.0 HD1 A:HIS501 4.0 0.2 1.0 CG A:GLU451 4.0 63.2 1.0 HG3 A:GLU451 4.0 62.1 1.0 CG A:GLU385 4.1 64.2 1.0 N A:ILE449 4.2 54.5 1.0 CB A:ASP500 4.2 22.2 1.0 HG3 A:GLU385 4.2 62.3 1.0 HB2 A:ASP448 4.2 33.3 1.0 CA A:ASP498 4.2 73.3 1.0 C A:ASP448 4.4 40.3 1.0 HB3 A:GLU385 4.4 33.0 1.0 CB A:GLU451 4.4 1.1 1.0 C A:ASP447 4.5 12.2 1.0 H A:ASP500 4.6 11.3 1.0 HB2 A:GLU385 4.6 31.1 1.0 O A:ASP498 4.7 11.1 1.0 N A:ASP448 4.7 34.0 1.0 CB A:GLU385 4.7 23.3 1.0 HB3 A:ASP498 4.7 25.4 1.0 ND1 A:HIS501 4.7 64.1 1.0 C A:ASP498 4.7 23.4 1.0 HB3 A:ASP500 4.7 41.4 1.0 HE1 A:HIS501 4.8 72.1 1.0 H A:HIS501 4.8 43.4 1.0 HB3 A:ASP448 4.9 43.1 1.0 C A:ILE449 4.9 11.0 1.0 HG2 A:GLU451 4.9 54.3 1.0 HB3 A:GLU451 5.0 34.1 1.0 HG2 A:GLU385 5.0 74.3 1.0

Calcium binding site 2 out of 2 in the First CA2+ Binding Domain of the Na,Ca-Exchanger (NCX1)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of First CA2+ Binding Domain of the Na,Ca-Exchanger (NCX1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca650 b:1.2 occ:1.00 OE2 A:GLU451 1.8 13.3 1.0 OE2 A:GLU454 1.8 41.3 1.0 OD1 A:ASP447 1.8 3.1 1.0 OD1 A:ASP421 1.9 72.3 1.0 OD2 A:ASP447 2.0 3.4 1.0 CG A:ASP447 2.3 34.4 1.0 CD A:GLU454 2.7 74.2 1.0 OE1 A:GLU454 2.8 63.2 1.0 CD A:GLU451 2.9 14.2 1.0 CG A:ASP421 3.0 71.1 1.0 HB3 A:ASP421 3.0 20.2 1.0 HG2 A:GLU451 3.2 54.3 1.0 HA A:ASP421 3.4 75.1 1.0 CB A:ASP421 3.4 1.1 1.0 CG A:GLU451 3.6 63.2 1.0 CB A:ASP447 3.8 53.2 1.0 OE1 A:GLU451 3.9 3.3 1.0 HB A:ILE449 3.9 10.4 1.0 CA A:ASP421 4.0 11.2 1.0 OD2 A:ASP421 4.0 43.2 1.0 CG A:GLU454 4.1 64.4 1.0 HB3 A:ASP447 4.2 32.5 1.0 O A:ASP447 4.2 32.2 1.0 HB2 A:ASP447 4.2 15.2 1.0 HG2 A:GLU454 4.3 5.0 1.0 HG3 A:GLU451 4.4 62.1 1.0 HB2 A:ASP421 4.4 72.2 1.0 HB3 A:GLU451 4.5 34.1 1.0 HE2 A:TYR422 4.5 54.2 1.0 H A:ILE449 4.5 73.0 1.0 HG12 A:ILE449 4.6 2.4 1.0 C A:ASP447 4.6 12.2 1.0 C A:ASP421 4.7 41.1 1.0 O A:ASP421 4.7 65.2 1.0 HG3 A:GLU454 4.7 72.4 1.0 CB A:GLU451 4.7 1.1 1.0 CA A:ASP447 4.8 55.1 1.0 CE2 A:TYR422 4.8 4.2 1.0 H A:ASP447 4.8 53.1 1.0 HB3 A:GLU454 4.8 54.5 1.0 CB A:ILE449 4.9 52.0 1.0 CB A:GLU454 5.0 53.1 1.0

M.Hilge, J.Aelen, G.W.Vuister. Ca(2+) Regulation in the Na(+)/Ca(2+) Exchanger Involves Two Markedly Different Ca(2+) Sensors Mol.Cell V. 22 15 2006.
ISSN: ISSN 1097-2765
PubMed: 16600866
DOI: 10.1016/J.MOLCEL.2006.03.008