Calcium in PDB 2fx6: Bovine Trypsin Complexed with 2-Aminobenzamidazole

All present enzymatic activity of Bovine Trypsin Complexed with 2-Aminobenzamidazole:
3.4.21.4;

The structure of Bovine Trypsin Complexed with 2-Aminobenzamidazole, PDB code: 2fx6 was solved by B.A.Katz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	7.00 / 1.57
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	63.710, 63.200, 69.500, 90.00, 90.00, 90.00
R / Rfree (%)	20.2 / 21.5

The binding sites of Calcium atom in the Bovine Trypsin Complexed with 2-Aminobenzamidazole (pdb code 2fx6). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Bovine Trypsin Complexed with 2-Aminobenzamidazole, PDB code: 2fx6:

Calcium binding site 1 out of 1 in the Bovine Trypsin Complexed with 2-Aminobenzamidazole


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Bovine Trypsin Complexed with 2-Aminobenzamidazole within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca247 b:27.1 occ:1.00 O A:VAL75 2.2 14.3 1.0 O A:ASN72 2.2 12.1 1.0 O A:HOH560 2.3 16.6 1.0 O A:HOH248 2.3 14.8 1.0 OE2 A:GLU70 2.3 14.6 1.0 OE2 A:GLU80 2.4 15.2 1.0 CD A:GLU70 3.3 17.3 1.0 C A:VAL75 3.3 17.0 1.0 C A:ASN72 3.4 15.6 1.0 CD A:GLU80 3.5 16.4 1.0 OE1 A:GLU70 3.6 16.6 1.0 CG A:GLU80 3.9 16.6 1.0 CA A:VAL76 4.0 17.7 1.0 N A:VAL76 4.0 15.6 1.0 N A:VAL75 4.0 16.9 1.0 CA A:ILE73 4.1 16.0 1.0 N A:GLU77 4.1 17.9 1.0 N A:ILE73 4.2 15.3 1.0 CA A:VAL75 4.2 17.8 1.0 N A:ASN72 4.3 14.8 1.0 OE2 A:GLU77 4.3 18.4 1.0 CA A:ASN72 4.3 15.2 1.0 O A:HOH381 4.3 15.0 1.0 C A:ILE73 4.4 15.0 1.0 CG A:GLU77 4.5 19.4 1.0 CB A:ASN72 4.5 16.4 1.0 OE1 A:GLU80 4.5 16.6 1.0 C A:VAL76 4.6 20.3 1.0 N A:ASP71 4.6 15.6 1.0 CG A:GLU70 4.6 14.3 1.0 N A:ASN74 4.7 14.6 1.0 CB A:GLU70 4.8 15.0 1.0 O A:ILE73 4.8 15.3 1.0 CA A:GLU70 4.8 13.0 1.0 CB A:VAL75 4.8 17.5 1.0 CD A:GLU77 4.9 21.1 1.0 CB A:GLU77 4.9 19.2 1.0 C A:ASP71 5.0 17.4 1.0

M.E.Mcgrath, P.A.Sprengeler, B.Hirschbein, J.R.Somoza, I.Lehoux, J.W.Janc, E.Gjerstad, M.Graupe, A.Estiarte, C.Venkataramani, Y.Liu, R.Yee, J.D.Ho, M.J.Green, C.-S.Lee, L.Liu, V.Tai, J.Spencer, D.Sperandio, B.A.Katz. Structure-Guided Design of Peptide-Based Tryptase Inhibitors. Biochemistry V. 45 5964 2006.
ISSN: ISSN 0006-2960
PubMed: 16681368
DOI: 10.1021/BI060173M