Calcium in PDB 2ga9: Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S

All present enzymatic activity of Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S:
2.1.1.57; 2.7.7.19;

The structure of Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S, PDB code: 2ga9 was solved by C.M.Moure, B.R.Bowman, P.D.Gershon, F.A.Quiocho, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	70.050, 91.690, 133.700, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 26

The binding sites of Calcium atom in the Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S (pdb code 2ga9). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S, PDB code: 2ga9:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca480 b:37.0 occ:1.00 O3B D:AGS482 2.2 56.2 1.0 O D:HOH494 2.4 27.3 1.0 O3A D:AGS482 2.5 55.9 1.0 OD2 D:ASP204 2.5 31.9 1.0 OD2 D:ASP202 2.6 43.3 1.0 PB D:AGS482 2.8 56.5 1.0 OD1 D:ASP204 3.0 29.2 1.0 CG D:ASP204 3.1 28.2 1.0 O1B D:AGS482 3.2 58.8 1.0 CG D:ASP202 3.6 43.1 1.0 PA D:AGS482 3.7 51.2 1.0 PG D:AGS482 3.7 53.2 1.0 O1A D:AGS482 3.7 52.0 1.0 OD1 D:ASP202 3.8 46.0 1.0 O D:HOH607 4.0 39.2 1.0 CA D:CA481 4.1 71.1 1.0 O D:HOH621 4.2 43.5 1.0 O2G D:AGS482 4.3 58.3 1.0 O D:HOH488 4.3 19.5 1.0 O2B D:AGS482 4.4 57.4 1.0 O D:ASP202 4.4 40.3 1.0 N D:SER188 4.5 28.4 1.0 S1G D:AGS482 4.5 55.7 1.0 CB D:ASP204 4.5 29.0 1.0 CB D:SER188 4.6 32.4 1.0 O5' D:AGS482 4.6 50.8 1.0 C5' D:AGS482 4.7 46.4 1.0 OG D:SER188 4.7 35.7 1.0 O3G D:AGS482 4.8 57.4 1.0 C D:ASP202 4.8 39.4 1.0 N D:ASP204 4.9 31.3 1.0 O2A D:AGS482 4.9 55.0 1.0 CB D:ASP202 4.9 42.0 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound Atp-Gamma-S within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca481 b:71.1 occ:1.00 O D:HOH621 2.2 43.5 1.0 OD1 D:ASP204 2.3 29.2 1.0 OD1 D:ASP202 2.4 46.0 1.0 CG D:ASP204 3.5 28.2 1.0 CG D:ASP202 3.5 43.1 1.0 OD2 D:ASP202 4.0 43.3 1.0 OD1 D:ASP253 4.0 31.1 1.0 OD2 D:ASP253 4.0 29.2 1.0 CA D:CA480 4.1 37.0 1.0 OD2 D:ASP204 4.3 31.9 1.0 CB D:ASP204 4.4 29.0 1.0 CG D:ASP253 4.5 27.5 1.0 CA D:ASP204 4.6 29.2 1.0 CB D:ASP202 4.7 42.0 1.0 O D:HOH547 4.8 50.1 1.0 O D:HOH499 4.8 31.6 1.0 O1A D:AGS482 4.9 52.0 1.0

C.M.Moure, B.R.Bowman, P.D.Gershon, F.A.Quiocho. Crystal Structures of the Vaccinia Virus Polyadenylate Polymerase Heterodimer: Insights Into Atp Selectivity and Processivity. Mol.Cell V. 22 339 2006.
ISSN: ISSN 1097-2765
PubMed: 16678106
DOI: 10.1016/J.MOLCEL.2006.03.015