Calcium in PDB 2h0k: Crystal Structure of A Mutant of Rat Annexin A5

The structure of Crystal Structure of A Mutant of Rat Annexin A5, PDB code: 2h0k was solved by T.Granier, B.Langlois D'estaintot, B.Gallois, B.Tessier, A.Brisson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.59 / 2.76
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	51.108, 67.184, 112.313, 90.00, 94.79, 90.00
R / Rfree (%)	19.7 / 26.1

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 22;

Binding sites:

The binding sites of Calcium atom in the Crystal Structure of A Mutant of Rat Annexin A5 (pdb code 2h0k). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 22 binding sites of Calcium where determined in the Crystal Structure of A Mutant of Rat Annexin A5, PDB code: 2h0k:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca401 b:29.4 occ:1.00 OE1 A:GLU70 2.3 28.9 1.0 O A:GLY30 2.3 31.2 1.0 O A:MET26 2.3 27.4 1.0 O A:GLY28 2.6 26.4 1.0 OE2 A:GLU70 2.6 29.8 1.0 CD A:GLU70 2.8 30.2 1.0 C A:MET26 3.5 27.4 1.0 C A:GLY30 3.5 31.6 1.0 C A:GLY28 3.8 28.2 1.0 OG1 A:THR31 4.0 31.1 1.0 N A:GLY30 4.1 28.5 1.0 N A:GLY28 4.2 29.4 1.0 CA A:MET26 4.2 25.6 1.0 CG A:GLU70 4.3 30.0 1.0 CA A:GLY30 4.3 30.2 1.0 C A:LEU29 4.5 27.5 1.0 N A:THR31 4.5 32.0 1.0 N A:GLU27 4.6 28.1 1.0 CA A:GLY28 4.6 28.4 1.0 CD1 B:LEU29 4.7 23.6 1.0 CA A:THR31 4.8 30.8 1.0 N A:LEU29 4.8 27.8 1.0 CB A:MET26 4.8 23.6 1.0 C A:GLU27 4.9 29.8 1.0 CA A:GLU27 4.9 29.5 1.0 CA A:LEU29 4.9 27.6 1.0

Calcium binding site 2 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca402 b:28.6 occ:1.00 O A:LEU71 2.3 30.7 1.0 OE1 A:GLU76 2.3 29.7 1.0 O A:LYS68 2.3 31.4 1.0 O A:HOH477 2.9 25.0 1.0 CD A:GLU76 3.2 29.6 1.0 OE2 A:GLU76 3.3 29.2 1.0 C A:LEU71 3.5 30.2 1.0 C A:LYS68 3.6 32.1 1.0 CA A:THR72 4.2 31.6 1.0 N A:THR72 4.3 30.9 1.0 N A:LEU71 4.4 29.3 1.0 CA A:SER69 4.4 31.8 1.0 N A:SER69 4.4 31.6 1.0 CA A:LYS68 4.5 31.7 1.0 CA A:LEU71 4.5 28.6 1.0 C A:SER69 4.6 32.3 1.0 CG A:GLU76 4.6 28.8 1.0 OG1 A:THR72 4.7 29.2 1.0 O A:SER69 4.9 33.4 1.0 CB A:THR72 4.9 30.5 1.0 N A:GLU70 4.9 31.9 1.0 CB A:GLU76 5.0 29.5 1.0

Calcium binding site 3 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca403 b:26.0 occ:1.00 O A:THR31 2.3 29.8 1.0 OE1 A:GLU33 2.3 24.6 1.0 CD A:GLU33 3.2 25.8 1.0 OE2 A:GLU33 3.3 26.3 1.0 C A:THR31 3.5 30.2 1.0 N A:THR31 4.0 32.0 1.0 O B:LEU29 4.0 25.5 1.0 CA A:THR31 4.3 30.8 1.0 N A:ASP32 4.5 28.6 1.0 N A:GLU33 4.6 27.3 1.0 CG A:GLU33 4.6 26.0 1.0 CA A:ASP32 4.6 27.1 1.0 CB A:THR31 4.7 30.4 1.0 O B:GLU27 4.9 24.3 1.0

Calcium binding site 4 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca404 b:36.2 occ:0.70 O A:GLY100 2.3 41.5 1.0 O A:LEU98 2.3 33.8 1.0 OD2 A:ASP142 2.3 35.0 1.0 C A:GLY100 3.2 43.9 1.0 OG1 A:THR103 3.3 36.7 1.0 O A:ALA101 3.4 42.4 1.0 CG A:ASP142 3.5 34.9 1.0 C A:LEU98 3.5 32.5 1.0 C A:ALA101 3.7 43.7 1.0 N A:ALA101 3.9 45.0 1.0 CA A:ALA101 3.9 44.8 1.0 N A:GLY100 4.0 42.6 1.0 C A:LYS99 4.0 41.2 1.0 O A:LYS99 4.1 39.1 1.0 CA A:GLY100 4.2 43.4 1.0 N A:THR103 4.3 37.5 1.0 CB A:ASP142 4.3 32.2 1.0 OD1 A:ASP142 4.4 34.8 1.0 N A:LYS99 4.4 36.1 1.0 CA A:LEU98 4.4 29.9 1.0 CB A:THR103 4.5 36.2 1.0 CA A:THR103 4.5 36.0 1.0 N A:GLY102 4.5 43.0 1.0 C A:GLY102 4.6 39.9 1.0 CA A:LYS99 4.6 40.2 1.0 O A:GLY102 4.9 39.1 1.0

Calcium binding site 5 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca412 b:20.9 occ:1.00 O A:GLU226 2.3 22.8 1.0 OG1 A:THR187 2.3 21.9 1.0 CB A:THR187 3.3 22.0 1.0 C A:GLU226 3.5 23.0 1.0 N A:THR187 4.0 21.3 1.0 CA A:THR187 4.3 21.9 1.0 CA A:GLU226 4.3 23.7 1.0 C A:GLY186 4.3 21.9 1.0 CG2 A:THR187 4.3 22.0 1.0 OE2 A:GLU189 4.4 20.0 1.0 OE1 A:GLU226 4.4 23.4 1.0 N A:THR227 4.5 24.4 1.0 CA A:GLY186 4.7 22.2 1.0 CB A:GLU226 4.7 23.0 1.0 CA A:THR227 4.7 24.4 1.0 O A:GLY186 4.8 21.8 1.0 CG2 A:THR227 4.9 24.3 1.0

Calcium binding site 6 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca406 b:37.6 occ:0.50 O A:THR103 2.3 35.8 1.0 OE1 A:GLU105 2.3 40.4 1.0 OE2 A:GLU105 3.0 42.2 1.0 CD A:GLU105 3.0 39.8 1.0 C A:THR103 3.5 34.2 1.0 N A:THR103 4.0 37.5 1.0 CA A:THR103 4.2 36.0 1.0 C A:GLY102 4.4 39.9 1.0 N A:ASP104 4.5 30.9 1.0 CG A:GLU105 4.5 39.5 1.0 N A:GLU105 4.7 30.4 1.0 CA A:ASP104 4.7 29.1 1.0 CA A:GLY102 4.8 41.5 1.0 CB A:THR103 4.8 36.2 1.0 O A:GLY102 4.9 39.1 1.0

Calcium binding site 7 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca409 b:21.4 occ:1.00 O A:THR187 2.3 22.4 1.0 OE1 A:GLU189 2.3 20.9 1.0 O A:HOH415 2.3 19.9 1.0 OE2 A:GLU189 2.9 20.0 1.0 CD A:GLU189 3.0 19.8 1.0 O A:HOH430 3.4 11.7 1.0 C A:THR187 3.5 23.1 1.0 N A:THR187 4.3 21.3 1.0 OH A:TYR146 4.4 15.9 1.0 CA A:THR187 4.4 21.9 1.0 CG A:GLU189 4.5 18.8 1.0 N A:GLU189 4.5 23.3 1.0 N A:ASP188 4.5 23.5 1.0 CA A:ASP188 4.6 23.5 1.0 CB A:THR187 4.9 22.0 1.0

Calcium binding site 8 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca410 b:29.2 occ:1.00 OD2 A:ASP301 2.3 27.3 1.0 O A:HOH416 2.3 28.1 1.0 O A:MET257 2.3 29.0 1.0 O A:GLY261 2.3 32.6 1.0 O A:GLY259 2.4 32.9 1.0 OD1 A:ASP301 2.8 27.6 1.0 CG A:ASP301 2.9 28.7 1.0 C A:MET257 3.5 30.1 1.0 C A:GLY259 3.5 36.3 1.0 C A:GLY261 3.5 33.4 1.0 C A:ALA260 4.0 37.2 1.0 O A:ALA260 4.1 38.1 1.0 N A:GLY261 4.1 35.1 1.0 N A:GLY259 4.2 37.3 1.0 CA A:MET257 4.2 28.3 1.0 C A:LYS258 4.3 37.0 1.0 CA A:GLY261 4.3 34.1 1.0 N A:ALA260 4.4 37.6 1.0 CB A:ASP301 4.4 27.7 1.0 OG1 A:THR262 4.4 31.0 1.0 CA A:GLY259 4.4 37.5 1.0 N A:LYS258 4.4 33.4 1.0 CA A:ALA260 4.5 37.9 1.0 O A:LYS258 4.5 38.3 1.0 N A:THR262 4.6 32.8 1.0 CA A:LYS258 4.6 36.5 1.0 CA A:THR262 4.8 32.3 1.0 CB A:MET257 4.9 27.6 1.0

Calcium binding site 9 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca408 b:26.7 occ:1.00 O A:ASP224 2.3 27.7 1.0 OE2 A:GLU232 2.3 27.9 1.0 O A:HOH417 2.3 21.7 1.0 O A:THR227 2.6 25.3 1.0 OD1 A:ASP224 3.1 28.5 1.0 C A:ASP224 3.4 27.1 1.0 CD A:GLU232 3.5 27.0 1.0 C A:THR227 3.7 24.9 1.0 CG A:ASP224 3.8 28.7 1.0 CA A:ASP224 4.0 26.6 1.0 CA A:SER228 4.2 24.7 1.0 OE1 A:GLU232 4.2 29.9 1.0 CB A:SER228 4.3 24.6 1.0 N A:SER228 4.4 25.6 1.0 OD2 A:ASP224 4.4 29.2 1.0 N A:ARG225 4.5 26.7 1.0 CB A:ASP224 4.5 27.6 1.0 CG A:GLU232 4.6 28.4 1.0 N A:THR227 4.6 24.4 1.0 CA A:THR227 4.8 24.4 1.0 CA A:ARG225 4.8 26.8 1.0 O A:ILE223 4.9 23.3 1.0 C A:ARG225 4.9 25.9 1.0

Calcium binding site 10 out of 22 in the Crystal Structure of A Mutant of Rat Annexin A5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Crystal Structure of A Mutant of Rat Annexin A5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca407 b:22.4 occ:1.00 O A:GLY186 2.3 21.8 1.0 O A:GLY181 2.3 23.5 1.0 O A:HOH418 2.3 17.8 1.0 OE2 A:GLU226 2.3 23.6 1.0 OE1 A:GLU226 2.3 23.4 1.0 O A:LYS184 2.3 24.8 1.0 CD A:GLU226 2.7 24.0 1.0 C A:GLY181 3.4 23.9 1.0 C A:GLY186 3.4 21.9 1.0 C A:LYS184 3.6 24.8 1.0 N A:GLY186 3.9 22.0 1.0 CA A:GLY186 4.1 22.2 1.0 CG A:GLU226 4.2 23.6 1.0 CA A:GLY181 4.2 22.4 1.0 OG1 A:THR187 4.3 21.9 1.0 N A:LYS184 4.3 24.2 1.0 N A:GLU182 4.4 23.8 1.0 CA A:LYS184 4.4 25.2 1.0 CA A:GLU182 4.5 22.9 1.0 N A:THR187 4.5 21.3 1.0 C A:TRP185 4.5 22.4 1.0 N A:TRP185 4.6 23.6 1.0 C A:GLU182 4.6 23.3 1.0 O A:GLU182 4.6 23.9 1.0 CB A:LYS184 4.7 24.7 1.0 CA A:THR187 4.7 21.9 1.0 CA A:TRP185 4.7 22.5 1.0

A.Bouter, C.Gounou, R.Berat, S.Tan, B.Gallois, T.Granier, B.L.D'estaintot, E.Poschl, B.Brachvogel, A.R.Brisson. Annexin-A5 Assembled Into Two-Dimensional Arrays Promotes Cell Membrane Repair. Nat Commun V. 2 270 2011.
ISSN: ESSN 2041-1723
PubMed: 21468022
DOI: 10.1038/NCOMMS1270