Calcium in PDB 2hty: N1 Neuraminidase
Protein crystallography data
The structure of N1 Neuraminidase, PDB code: 2hty
was solved by
R.J.Russell,
L.F.Haire,
D.J.Stevens,
P.J.Collins,
Y.P.Lin,
G.M.Blackburn,
A.J.Hay,
S.J.Gamblin,
J.J.Skehel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
30.00 /
2.50
|
|
Space group
|
C 2 2 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
200.210,
200.770,
211.680,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
23.2 /
26.2
|
Calcium Binding Sites:
The binding sites of Calcium atom in the N1 Neuraminidase
(pdb code 2hty). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
N1 Neuraminidase, PDB code: 2hty:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 2hty
Go back to
Calcium Binding Sites List in 2hty
Calcium binding site 1 out
of 8 in the N1 Neuraminidase
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of N1 Neuraminidase within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca991
b:21.6
occ:1.00
|
O
|
A:TYR347
|
2.3
|
24.1
|
1.0
|
|
OD1
|
A:ASP324
|
2.3
|
22.6
|
1.0
|
|
O
|
A:GLY297
|
2.5
|
17.4
|
1.0
|
|
O
|
A:ASP293
|
2.5
|
12.8
|
1.0
|
|
C
|
A:TYR347
|
3.1
|
23.8
|
1.0
|
|
O
|
A:GLY345
|
3.2
|
38.2
|
1.0
|
|
C
|
A:GLY345
|
3.3
|
38.4
|
1.0
|
|
N
|
A:TYR347
|
3.3
|
29.8
|
1.0
|
|
CG
|
A:ASP324
|
3.4
|
22.4
|
1.0
|
|
CA
|
A:GLY345
|
3.6
|
38.8
|
1.0
|
|
C
|
A:GLY297
|
3.6
|
16.5
|
1.0
|
|
C
|
A:ASP293
|
3.7
|
14.4
|
1.0
|
|
N
|
A:GLY348
|
3.8
|
21.6
|
1.0
|
|
CA
|
A:GLY348
|
3.8
|
19.7
|
1.0
|
|
N
|
A:ALA346
|
3.9
|
37.3
|
1.0
|
|
CA
|
A:TYR347
|
3.9
|
26.1
|
1.0
|
|
OD2
|
A:ASP324
|
4.1
|
23.4
|
1.0
|
|
CB
|
A:ASP324
|
4.2
|
20.1
|
1.0
|
|
C
|
A:ALA346
|
4.2
|
33.1
|
1.0
|
|
CA
|
A:ASN294
|
4.2
|
15.0
|
1.0
|
|
CA
|
A:ALA346
|
4.2
|
34.0
|
1.0
|
|
N
|
A:GLY297
|
4.2
|
14.3
|
1.0
|
|
O
|
A:HOH1205
|
4.3
|
20.2
|
1.0
|
|
N
|
A:ASN294
|
4.4
|
14.6
|
1.0
|
|
CA
|
A:GLY297
|
4.5
|
14.2
|
1.0
|
|
N
|
A:SER298
|
4.5
|
18.4
|
1.0
|
|
CA
|
A:SER298
|
4.7
|
19.2
|
1.0
|
|
C
|
A:ASN294
|
4.7
|
15.7
|
1.0
|
|
O
|
A:PRO326
|
4.8
|
12.1
|
1.0
|
|
CA
|
A:ASP293
|
4.9
|
15.0
|
1.0
|
|
OD2
|
A:ASP293
|
4.9
|
19.8
|
1.0
|
|
O
|
A:HOH1152
|
4.9
|
17.0
|
1.0
|
|
O
|
A:ASN294
|
5.0
|
15.8
|
1.0
|
|
CB
|
A:TYR347
|
5.0
|
27.6
|
1.0
|
|
Calcium binding site 2 out
of 8 in 2hty
Go back to
Calcium Binding Sites List in 2hty
Calcium binding site 2 out
of 8 in the N1 Neuraminidase
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of N1 Neuraminidase within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca992
b:21.8
occ:1.00
|
O
|
B:TYR347
|
2.1
|
26.5
|
1.0
|
|
O
|
B:ASP293
|
2.3
|
16.6
|
1.0
|
|
OD1
|
B:ASP324
|
2.4
|
22.6
|
1.0
|
|
O
|
B:GLY297
|
2.4
|
23.0
|
1.0
|
|
C
|
B:TYR347
|
3.2
|
26.3
|
1.0
|
|
O
|
B:GLY345
|
3.2
|
37.8
|
1.0
|
|
CG
|
B:ASP324
|
3.4
|
22.5
|
1.0
|
|
C
|
B:GLY345
|
3.5
|
38.3
|
1.0
|
|
C
|
B:ASP293
|
3.6
|
16.8
|
1.0
|
|
C
|
B:GLY297
|
3.6
|
21.2
|
1.0
|
|
N
|
B:TYR347
|
3.7
|
32.0
|
1.0
|
|
CA
|
B:GLY345
|
3.7
|
38.8
|
1.0
|
|
CA
|
B:GLY348
|
3.8
|
21.8
|
1.0
|
|
N
|
B:GLY348
|
4.0
|
23.6
|
1.0
|
|
CA
|
B:TYR347
|
4.1
|
28.5
|
1.0
|
|
OD2
|
B:ASP324
|
4.2
|
22.9
|
1.0
|
|
CB
|
B:ASP324
|
4.2
|
21.9
|
1.0
|
|
CA
|
B:ASN294
|
4.3
|
18.4
|
1.0
|
|
N
|
B:GLY297
|
4.3
|
19.1
|
1.0
|
|
N
|
B:ALA346
|
4.3
|
38.5
|
1.0
|
|
N
|
B:ASN294
|
4.4
|
16.9
|
1.0
|
|
CA
|
B:GLY297
|
4.5
|
20.8
|
1.0
|
|
N
|
B:SER298
|
4.5
|
22.1
|
1.0
|
|
OD2
|
B:ASP293
|
4.6
|
22.3
|
1.0
|
|
CA
|
B:ASP293
|
4.6
|
17.3
|
1.0
|
|
CA
|
B:SER298
|
4.6
|
22.4
|
1.0
|
|
CB
|
B:ASP293
|
4.7
|
18.4
|
1.0
|
|
C
|
B:ALA346
|
4.7
|
34.9
|
1.0
|
|
C
|
B:ASN294
|
4.7
|
19.4
|
1.0
|
|
O
|
B:PRO326
|
4.7
|
16.8
|
1.0
|
|
N
|
B:ASP293
|
4.8
|
17.9
|
1.0
|
|
CA
|
B:ALA346
|
4.8
|
36.4
|
1.0
|
|
CG
|
B:ASP293
|
5.0
|
21.9
|
1.0
|
|
Calcium binding site 3 out
of 8 in 2hty
Go back to
Calcium Binding Sites List in 2hty
Calcium binding site 3 out
of 8 in the N1 Neuraminidase
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of N1 Neuraminidase within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca993
b:22.1
occ:1.00
|
O
|
C:TYR347
|
2.1
|
23.8
|
1.0
|
|
OD1
|
C:ASP324
|
2.3
|
18.9
|
1.0
|
|
O
|
C:GLY297
|
2.4
|
14.0
|
1.0
|
|
O
|
C:ASP293
|
2.4
|
10.2
|
1.0
|
|
O
|
C:GLY345
|
2.8
|
29.9
|
1.0
|
|
C
|
C:TYR347
|
3.0
|
22.8
|
1.0
|
|
N
|
C:TYR347
|
3.4
|
28.1
|
1.0
|
|
CG
|
C:ASP324
|
3.4
|
17.5
|
1.0
|
|
C
|
C:GLY345
|
3.5
|
31.2
|
1.0
|
|
C
|
C:GLY297
|
3.6
|
12.8
|
1.0
|
|
C
|
C:ASP293
|
3.7
|
11.3
|
1.0
|
|
N
|
C:GLY348
|
3.8
|
20.1
|
1.0
|
|
CA
|
C:GLY348
|
3.8
|
18.2
|
1.0
|
|
CA
|
C:TYR347
|
3.9
|
24.9
|
1.0
|
|
CA
|
C:GLY345
|
4.0
|
31.3
|
1.0
|
|
OD2
|
C:ASP324
|
4.2
|
15.0
|
1.0
|
|
N
|
C:GLY297
|
4.2
|
12.1
|
1.0
|
|
CA
|
C:ASN294
|
4.3
|
10.3
|
1.0
|
|
N
|
C:ALA346
|
4.3
|
32.7
|
1.0
|
|
O
|
C:HOH1214
|
4.3
|
18.6
|
1.0
|
|
CB
|
C:ASP324
|
4.3
|
17.2
|
1.0
|
|
C
|
C:ALA346
|
4.4
|
31.1
|
1.0
|
|
N
|
C:ASN294
|
4.4
|
10.2
|
1.0
|
|
CA
|
C:GLY297
|
4.4
|
12.7
|
1.0
|
|
N
|
C:SER298
|
4.5
|
14.0
|
1.0
|
|
CA
|
C:SER298
|
4.6
|
14.3
|
1.0
|
|
CA
|
C:ALA346
|
4.6
|
31.7
|
1.0
|
|
C
|
C:ASN294
|
4.6
|
10.6
|
1.0
|
|
CA
|
C:ASP293
|
4.8
|
11.5
|
1.0
|
|
OD2
|
C:ASP293
|
4.8
|
19.1
|
1.0
|
|
CB
|
C:ASP293
|
4.9
|
13.7
|
1.0
|
|
O
|
C:PRO326
|
4.9
|
14.1
|
1.0
|
|
O
|
C:ASN294
|
5.0
|
9.9
|
1.0
|
|
N
|
C:ASP293
|
5.0
|
12.7
|
1.0
|
|
Calcium binding site 4 out
of 8 in 2hty
Go back to
Calcium Binding Sites List in 2hty
Calcium binding site 4 out
of 8 in the N1 Neuraminidase
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of N1 Neuraminidase within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca994
b:23.6
occ:1.00
|
OD1
|
D:ASP324
|
2.3
|
18.2
|
1.0
|
|
O
|
D:TYR347
|
2.3
|
24.5
|
1.0
|
|
O
|
D:ASP293
|
2.4
|
15.3
|
1.0
|
|
O
|
D:GLY297
|
2.5
|
15.8
|
1.0
|
|
O
|
D:GLY345
|
2.7
|
29.3
|
1.0
|
|
C
|
D:TYR347
|
3.2
|
22.8
|
1.0
|
|
C
|
D:GLY345
|
3.2
|
31.2
|
1.0
|
|
CG
|
D:ASP324
|
3.4
|
17.8
|
1.0
|
|
N
|
D:TYR347
|
3.5
|
27.0
|
1.0
|
|
C
|
D:GLY297
|
3.6
|
15.1
|
1.0
|
|
CA
|
D:GLY345
|
3.6
|
32.5
|
1.0
|
|
C
|
D:ASP293
|
3.6
|
16.2
|
1.0
|
|
N
|
D:GLY348
|
4.0
|
19.8
|
1.0
|
|
CA
|
D:GLY348
|
4.0
|
18.4
|
1.0
|
|
CA
|
D:TYR347
|
4.0
|
24.6
|
1.0
|
|
O
|
D:HOH1174
|
4.1
|
9.4
|
1.0
|
|
CB
|
D:ASP324
|
4.1
|
15.5
|
1.0
|
|
N
|
D:ALA346
|
4.2
|
31.4
|
1.0
|
|
N
|
D:GLY297
|
4.2
|
14.4
|
1.0
|
|
OD2
|
D:ASP324
|
4.3
|
20.0
|
1.0
|
|
CA
|
D:ASN294
|
4.4
|
16.2
|
1.0
|
|
N
|
D:ASN294
|
4.4
|
16.8
|
1.0
|
|
N
|
D:SER298
|
4.4
|
16.8
|
1.0
|
|
CA
|
D:GLY297
|
4.5
|
13.7
|
1.0
|
|
C
|
D:ALA346
|
4.5
|
29.2
|
1.0
|
|
CA
|
D:SER298
|
4.5
|
16.7
|
1.0
|
|
CA
|
D:ALA346
|
4.7
|
30.2
|
1.0
|
|
CA
|
D:ASP293
|
4.7
|
16.2
|
1.0
|
|
O
|
D:PRO326
|
4.7
|
15.2
|
1.0
|
|
C
|
D:ASN294
|
4.8
|
15.4
|
1.0
|
|
OD2
|
D:ASP293
|
4.8
|
16.8
|
1.0
|
|
CB
|
D:ASP293
|
4.8
|
16.2
|
1.0
|
|
N
|
D:ASP293
|
4.9
|
15.8
|
1.0
|
|
N
|
D:GLY345
|
5.0
|
32.4
|
1.0
|
|
Calcium binding site 5 out
of 8 in 2hty
Go back to
Calcium Binding Sites List in 2hty
Calcium binding site 5 out
of 8 in the N1 Neuraminidase
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of N1 Neuraminidase within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca995
b:28.3
occ:1.00
|
O
|
E:TYR347
|
2.3
|
33.4
|
1.0
|
|
OD1
|
E:ASP324
|
2.4
|
24.3
|
1.0
|
|
O
|
E:GLY297
|
2.4
|
28.2
|
1.0
|
|
O
|
E:ASP293
|
2.5
|
23.8
|
1.0
|
|
O
|
E:GLY345
|
2.8
|
39.8
|
1.0
|
|
C
|
E:GLY345
|
3.2
|
41.1
|
1.0
|
|
C
|
E:TYR347
|
3.3
|
33.3
|
1.0
|
|
CA
|
E:GLY345
|
3.3
|
42.4
|
1.0
|
|
CG
|
E:ASP324
|
3.5
|
22.8
|
1.0
|
|
C
|
E:GLY297
|
3.5
|
27.6
|
1.0
|
|
C
|
E:ASP293
|
3.7
|
24.7
|
1.0
|
|
N
|
E:TYR347
|
3.7
|
37.3
|
1.0
|
|
CA
|
E:GLY348
|
4.1
|
29.3
|
1.0
|
|
N
|
E:GLY348
|
4.1
|
30.8
|
1.0
|
|
N
|
E:ALA346
|
4.1
|
41.2
|
1.0
|
|
N
|
E:GLY297
|
4.1
|
27.6
|
1.0
|
|
CA
|
E:TYR347
|
4.2
|
35.7
|
1.0
|
|
CB
|
E:ASP324
|
4.2
|
21.3
|
1.0
|
|
OD2
|
E:ASP324
|
4.3
|
24.2
|
1.0
|
|
N
|
E:SER298
|
4.3
|
28.3
|
1.0
|
|
CA
|
E:GLY297
|
4.4
|
26.6
|
1.0
|
|
CA
|
E:ASN294
|
4.4
|
27.8
|
1.0
|
|
CA
|
E:SER298
|
4.5
|
27.0
|
1.0
|
|
N
|
E:ASN294
|
4.5
|
25.8
|
1.0
|
|
C
|
E:ALA346
|
4.6
|
39.2
|
1.0
|
|
CA
|
E:ASP293
|
4.7
|
24.8
|
1.0
|
|
CA
|
E:ALA346
|
4.7
|
39.6
|
1.0
|
|
CB
|
E:ASP293
|
4.8
|
25.4
|
1.0
|
|
O
|
E:PRO326
|
4.8
|
21.4
|
1.0
|
|
N
|
E:GLY345
|
4.8
|
42.9
|
1.0
|
|
C
|
E:ASN294
|
4.8
|
28.8
|
1.0
|
|
N
|
E:ASP293
|
4.8
|
25.6
|
1.0
|
|
Calcium binding site 6 out
of 8 in 2hty
Go back to
Calcium Binding Sites List in 2hty
Calcium binding site 6 out
of 8 in the N1 Neuraminidase
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of N1 Neuraminidase within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca996
b:46.0
occ:1.00
|
O
|
F:TYR347
|
2.2
|
38.6
|
1.0
|
|
OD1
|
F:ASP324
|
2.4
|
35.9
|
1.0
|
|
O
|
F:GLY297
|
2.5
|
36.4
|
1.0
|
|
O
|
F:ASP293
|
2.5
|
31.8
|
1.0
|
|
O
|
F:GLY345
|
2.9
|
48.0
|
1.0
|
|
C
|
F:TYR347
|
3.2
|
38.4
|
1.0
|
|
C
|
F:GLY345
|
3.3
|
48.4
|
1.0
|
|
CG
|
F:ASP324
|
3.4
|
38.0
|
1.0
|
|
C
|
F:GLY297
|
3.5
|
37.0
|
1.0
|
|
N
|
F:TYR347
|
3.6
|
43.7
|
1.0
|
|
CA
|
F:GLY345
|
3.6
|
49.1
|
1.0
|
|
C
|
F:ASP293
|
3.7
|
31.2
|
1.0
|
|
N
|
F:GLY348
|
4.0
|
36.1
|
1.0
|
|
CA
|
F:GLY348
|
4.0
|
33.8
|
1.0
|
|
CA
|
F:TYR347
|
4.0
|
40.0
|
1.0
|
|
N
|
F:GLY297
|
4.1
|
36.7
|
1.0
|
|
N
|
F:ALA346
|
4.2
|
48.4
|
1.0
|
|
CB
|
F:ASP324
|
4.2
|
37.1
|
1.0
|
|
OD2
|
F:ASP324
|
4.3
|
38.7
|
1.0
|
|
N
|
F:SER298
|
4.3
|
37.6
|
1.0
|
|
CA
|
F:GLY297
|
4.3
|
37.0
|
1.0
|
|
CA
|
F:SER298
|
4.4
|
38.2
|
1.0
|
|
C
|
F:ALA346
|
4.4
|
47.0
|
1.0
|
|
CA
|
F:ASN294
|
4.5
|
31.9
|
1.0
|
|
N
|
F:ASN294
|
4.6
|
31.2
|
1.0
|
|
O
|
F:PRO326
|
4.6
|
34.7
|
1.0
|
|
CA
|
F:ALA346
|
4.7
|
47.5
|
1.0
|
|
CA
|
F:ASP293
|
4.7
|
30.5
|
1.0
|
|
CB
|
F:ASP293
|
4.8
|
31.0
|
1.0
|
|
C
|
F:ASN294
|
4.8
|
32.5
|
1.0
|
|
N
|
F:ASP293
|
4.9
|
30.0
|
1.0
|
|
Calcium binding site 7 out
of 8 in 2hty
Go back to
Calcium Binding Sites List in 2hty
Calcium binding site 7 out
of 8 in the N1 Neuraminidase
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of N1 Neuraminidase within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca997
b:29.2
occ:1.00
|
OD1
|
G:ASP324
|
2.2
|
16.7
|
1.0
|
|
O
|
G:HOH1147
|
2.2
|
39.1
|
1.0
|
|
O
|
G:TYR347
|
2.3
|
22.9
|
1.0
|
|
O
|
G:GLY297
|
2.4
|
15.4
|
1.0
|
|
O
|
G:ASP293
|
2.6
|
22.8
|
1.0
|
|
C
|
G:TYR347
|
3.2
|
23.1
|
1.0
|
|
CG
|
G:ASP324
|
3.2
|
16.9
|
1.0
|
|
C
|
G:GLY297
|
3.4
|
15.2
|
1.0
|
|
C
|
G:GLY345
|
3.5
|
33.9
|
1.0
|
|
N
|
G:TYR347
|
3.6
|
28.9
|
1.0
|
|
O
|
G:GLY345
|
3.6
|
36.0
|
1.0
|
|
CA
|
G:GLY345
|
3.6
|
33.8
|
1.0
|
|
C
|
G:ASP293
|
3.8
|
21.6
|
1.0
|
|
CA
|
G:GLY348
|
3.9
|
20.4
|
1.0
|
|
N
|
G:GLY348
|
3.9
|
21.7
|
1.0
|
|
OD2
|
G:ASP324
|
4.0
|
16.8
|
1.0
|
|
N
|
G:ALA346
|
4.0
|
35.3
|
1.0
|
|
CB
|
G:ASP324
|
4.1
|
17.7
|
1.0
|
|
CA
|
G:TYR347
|
4.1
|
25.4
|
1.0
|
|
N
|
G:GLY297
|
4.2
|
14.7
|
1.0
|
|
O
|
G:HOH1186
|
4.3
|
14.1
|
1.0
|
|
CA
|
G:GLY297
|
4.3
|
14.3
|
1.0
|
|
N
|
G:SER298
|
4.3
|
14.6
|
1.0
|
|
CA
|
G:SER298
|
4.5
|
15.8
|
1.0
|
|
CA
|
G:ASN294
|
4.5
|
19.9
|
1.0
|
|
C
|
G:ALA346
|
4.6
|
32.3
|
1.0
|
|
O
|
G:PRO326
|
4.6
|
17.5
|
1.0
|
|
N
|
G:ASN294
|
4.6
|
20.0
|
1.0
|
|
CA
|
G:ALA346
|
4.7
|
34.0
|
1.0
|
|
CA
|
G:ASP293
|
4.8
|
21.9
|
1.0
|
|
C
|
G:ASN294
|
4.9
|
19.0
|
1.0
|
|
CB
|
G:ASP293
|
4.9
|
21.6
|
1.0
|
|
N
|
G:ASP293
|
4.9
|
21.5
|
1.0
|
|
N
|
G:GLY345
|
5.0
|
33.4
|
1.0
|
|
Calcium binding site 8 out
of 8 in 2hty
Go back to
Calcium Binding Sites List in 2hty
Calcium binding site 8 out
of 8 in the N1 Neuraminidase
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of N1 Neuraminidase within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Ca998
b:40.2
occ:1.00
|
O
|
H:TYR347
|
2.2
|
46.8
|
1.0
|
|
OD1
|
H:ASP324
|
2.3
|
39.3
|
1.0
|
|
O
|
H:GLY297
|
2.5
|
40.5
|
1.0
|
|
O
|
H:ASP293
|
2.6
|
39.0
|
1.0
|
|
O
|
H:GLY345
|
2.8
|
52.5
|
1.0
|
|
C
|
H:GLY345
|
3.1
|
53.4
|
1.0
|
|
C
|
H:TYR347
|
3.2
|
45.9
|
1.0
|
|
CA
|
H:GLY345
|
3.4
|
54.8
|
1.0
|
|
C
|
H:GLY297
|
3.4
|
38.0
|
1.0
|
|
CG
|
H:ASP324
|
3.5
|
38.2
|
1.0
|
|
N
|
H:TYR347
|
3.6
|
50.0
|
1.0
|
|
C
|
H:ASP293
|
3.9
|
39.2
|
1.0
|
|
CA
|
H:GLY348
|
4.0
|
41.3
|
1.0
|
|
N
|
H:ALA346
|
4.0
|
53.0
|
1.0
|
|
N
|
H:GLY348
|
4.1
|
43.4
|
1.0
|
|
N
|
H:GLY297
|
4.1
|
37.2
|
1.0
|
|
CA
|
H:TYR347
|
4.2
|
47.7
|
1.0
|
|
CB
|
H:ASP324
|
4.2
|
37.2
|
1.0
|
|
N
|
H:SER298
|
4.2
|
36.8
|
1.0
|
|
OD2
|
H:ASP324
|
4.3
|
38.7
|
1.0
|
|
CA
|
H:GLY297
|
4.3
|
37.2
|
1.0
|
|
CA
|
H:SER298
|
4.4
|
35.3
|
1.0
|
|
O
|
H:PRO326
|
4.4
|
39.4
|
1.0
|
|
CA
|
H:ASN294
|
4.4
|
41.1
|
1.0
|
|
C
|
H:ALA346
|
4.5
|
52.3
|
1.0
|
|
CA
|
H:ALA346
|
4.6
|
52.8
|
1.0
|
|
N
|
H:ASN294
|
4.6
|
39.8
|
1.0
|
|
C
|
H:ASN294
|
4.8
|
40.8
|
1.0
|
|
N
|
H:GLY345
|
4.8
|
56.3
|
1.0
|
|
CA
|
H:ASP293
|
4.9
|
38.8
|
1.0
|
|
Reference:
R.J.Russell,
L.F.Haire,
D.J.Stevens,
P.J.Collins,
Y.P.Lin,
G.M.Blackburn,
A.J.Hay,
S.J.Gamblin,
J.J.Skehel.
The Structure of H5N1 Avian Influenza Neuraminidase Suggests New Opportunities For Drug Design. Nature V. 443 45 2006.
ISSN: ISSN 0028-0836
PubMed: 16915235
DOI: 10.1038/NATURE05114
Page generated: Fri Jul 12 12:50:26 2024
|
