Calcium in PDB 2iim: SH3 Domain of Human Lck

The structure of SH3 Domain of Human Lck, PDB code: 2iim was solved by J.Romir, C.Egerer-Sieber, Y.A.Muller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.00
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	50.310, 50.310, 46.370, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / 15.3

The structure of SH3 Domain of Human Lck also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Calcium atom in the SH3 Domain of Human Lck (pdb code 2iim). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the SH3 Domain of Human Lck, PDB code: 2iim:

Calcium binding site 1 out of 1 in the SH3 Domain of Human Lck


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of SH3 Domain of Human Lck within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca600 b:16.0 occ:1.00 ND2 A:ASN114 2.2 23.6 1.0 O A:HOH2003 2.4 22.1 1.0 O A:HOH2005 2.4 28.7 1.0 O A:HOH2004 2.4 11.4 1.0 CG A:ASN114 3.5 22.3 1.0 CB A:ASN114 4.1 12.6 1.0 O A:HOH2018 4.1 14.6 1.0 CA A:ASN114 4.4 9.1 1.0 OD1 A:ASN114 4.4 41.5 1.0 O A:ASN114 4.5 8.6 1.0 C A:ASN114 5.0 7.4 1.0

J.Romir, H.Lilie, C.Egerer-Sieber, F.Bauer, H.Sticht, Y.A.Muller. Crystal Structure Analysis and Solution Studies of Human Lck-SH3; Zinc-Induced Homodimerization Competes with the Binding of Proline-Rich Motifs. J.Mol.Biol. V. 365 1417 2007.
ISSN: ISSN 0022-2836
PubMed: 17118402
DOI: 10.1016/J.JMB.2006.10.058