Calcium in PDB 2ipx: Human Fibrillarin

The structure of Human Fibrillarin, PDB code: 2ipx was solved by J.Min, H.Wu, H.Zeng, P.Loppnau, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, A.N.Plotnikov, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.00 / 1.82
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	57.261, 57.261, 135.028, 90.00, 90.00, 90.00
R / Rfree (%)	20 / 24.6

The binding sites of Calcium atom in the Human Fibrillarin (pdb code 2ipx). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human Fibrillarin, PDB code: 2ipx:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Human Fibrillarin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Fibrillarin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca317 b:18.7 occ:1.00 O A:HOH4005 2.4 17.4 1.0 OG1 A:THR209 2.4 18.3 1.0 O A:HOH4006 2.4 18.2 1.0 O A:THR209 2.4 16.0 1.0 O A:HOH4027 2.6 21.7 1.0 C A:THR209 3.4 16.2 1.0 CB A:THR209 3.6 16.6 1.0 CA A:THR209 3.8 16.7 1.0 CG2 A:THR209 4.3 17.9 1.0 O A:HOH4092 4.6 34.6 1.0 N A:ASN210 4.6 15.9 1.0 O A:HOH4016 4.7 19.7 1.0 O A:HOH4014 4.8 20.9 1.0

Calcium binding site 2 out of 2 in the Human Fibrillarin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Fibrillarin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca318 b:36.8 occ:0.50 O A:HOH4101 2.8 65.4 1.0 O A:HOH4026 3.3 19.3 1.0 OE2 A:GLU290 3.3 24.6 1.0 O A:HOH4183 3.5 42.0 1.0 CD A:GLU290 4.3 24.0 1.0 NE2 A:GLN289 4.6 34.2 1.0 OE1 A:GLU290 4.6 20.5 1.0 O A:HOH4118 4.7 33.6 1.0

H.Wu, J.Min, H.Zeng, P.Loppnau, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, A.N.Plotnikov. The Crystal Structure of Human Fibrillarin in Complex with Sah To Be Published.