Calcium in PDB 2jg8: Crystallographic Structure of Human C1Q Globular Heads Complexed to Phosphatidyl-Serine

The structure of Crystallographic Structure of Human C1Q Globular Heads Complexed to Phosphatidyl-Serine, PDB code: 2jg8 was solved by H.Paidassi, P.Tacnet-Delorme, V.Garlatti, C.Darnault, B.Ghebrehiwet, C.Gaboriaud, G.J.Arlaud, P.Frachet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.94 / 2.05
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	48.090, 48.070, 84.700, 91.34, 93.34, 113.68
R / Rfree (%)	18.1 / 24.1

The binding sites of Calcium atom in the Crystallographic Structure of Human C1Q Globular Heads Complexed to Phosphatidyl-Serine (pdb code 2jg8). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystallographic Structure of Human C1Q Globular Heads Complexed to Phosphatidyl-Serine, PDB code: 2jg8:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystallographic Structure of Human C1Q Globular Heads Complexed to Phosphatidyl-Serine


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystallographic Structure of Human C1Q Globular Heads Complexed to Phosphatidyl-Serine within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1224 b:19.7 occ:1.00 OE1 B:GLN179 2.2 13.3 1.0 O B:TYR173 2.3 19.8 1.0 OE1 A:GLN177 2.3 17.7 1.0 OD2 B:ASP172 2.3 14.3 1.0 O C:HOH2044 2.5 14.9 1.0 CD B:GLN179 3.4 12.9 1.0 CG B:ASP172 3.4 15.5 1.0 CD A:GLN177 3.4 17.3 1.0 C B:TYR173 3.4 19.5 1.0 N B:TYR173 3.9 18.2 1.0 NE2 A:GLN177 4.0 18.6 1.0 O A:PHE176 4.0 15.8 1.0 CB B:GLN179 4.0 13.9 1.0 OD1 B:ASP172 4.0 13.8 1.0 NE2 C:GLN173 4.1 19.4 1.0 C B:ASP172 4.2 17.2 1.0 NE2 B:GLN179 4.2 13.4 1.0 CG B:GLN179 4.2 13.0 1.0 CA B:TYR173 4.3 19.2 1.0 N B:ALA174 4.3 19.4 1.0 CB B:ALA174 4.3 19.2 1.0 CB B:ASP172 4.4 15.8 1.0 CA B:ALA174 4.4 19.6 1.0 CA A:GLN177 4.4 14.8 1.0 CG A:GLN177 4.5 16.5 1.0 CB A:GLN177 4.6 14.9 1.0 CA B:ASP172 4.7 16.4 1.0 O B:ASP172 4.7 17.4 1.0 O C:HOH2043 4.8 12.4 1.0 C A:PHE176 5.0 15.7 1.0

Calcium binding site 2 out of 2 in the Crystallographic Structure of Human C1Q Globular Heads Complexed to Phosphatidyl-Serine


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystallographic Structure of Human C1Q Globular Heads Complexed to Phosphatidyl-Serine within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca1224 b:22.2 occ:1.00 OD2 E:ASP172 2.3 12.7 1.0 OE1 E:GLN179 2.3 15.3 1.0 OE1 D:GLN177 2.4 15.8 1.0 O E:TYR173 2.6 22.6 1.0 O F:HOH2044 2.7 14.3 1.0 CG E:ASP172 3.3 14.6 1.0 CD E:GLN179 3.4 14.7 1.0 CD D:GLN177 3.6 16.8 1.0 C E:TYR173 3.6 22.4 1.0 N E:TYR173 3.9 19.6 1.0 OD1 E:ASP172 4.0 13.0 1.0 CB E:GLN179 4.0 14.5 1.0 O D:PHE176 4.1 17.9 1.0 NE2 F:GLN173 4.1 22.1 1.0 NE2 E:GLN179 4.2 15.0 1.0 NE2 D:GLN177 4.2 17.8 1.0 C E:ASP172 4.3 18.2 1.0 CG E:GLN179 4.3 14.4 1.0 CB E:ASP172 4.4 16.0 1.0 CA E:TYR173 4.4 21.3 1.0 N E:ALA174 4.4 23.6 1.0 CB E:ALA174 4.5 25.2 1.0 CA D:GLN177 4.5 14.9 1.0 CA E:ALA174 4.6 25.7 1.0 CB D:GLN177 4.6 14.8 1.0 O F:HOH2043 4.6 17.4 1.0 CG D:GLN177 4.7 16.2 1.0 CA E:ASP172 4.7 16.8 1.0 O E:ASP172 4.8 17.8 1.0

H.Paidassi, P.Tacnet-Delorme, V.Garlatti, C.Darnault, B.Ghebrehiwet, C.Gaboriaud, G.J.Arlaud, P.Frachet. C1Q Binds Phosphatidylserine and Likely Acts As A Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol. V. 180 2329 2008.
ISSN: ISSN 0022-1767
PubMed: 18250442
DOI: 10.4049/JIMMUNOL.180.4.2329