Calcium in PDB 2jhh: Structure of Globular Heads of M-Ficolin at Acidic pH

The structure of Structure of Globular Heads of M-Ficolin at Acidic pH, PDB code: 2jhh was solved by V.Garlatti, L.Martin, E.Gout, J.B.Reiser, G.J.Arlaud, N.M.Thielens, C.Gaboriaud, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.03 / 1.70
Space group	P 3
Cell size a, b, c (Å), α, β, γ (°)	69.400, 69.400, 77.630, 90.00, 90.00, 120.00
R / Rfree (%)	21.9 / 25.2

The binding sites of Calcium atom in the Structure of Globular Heads of M-Ficolin at Acidic pH (pdb code 2jhh). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of Globular Heads of M-Ficolin at Acidic pH, PDB code: 2jhh:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of Globular Heads of M-Ficolin at Acidic pH


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Globular Heads of M-Ficolin at Acidic pH within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca400 b:25.3 occ:1.00 OD1 C:ASP235 2.3 22.6 1.0 O C:HOH2110 2.3 31.1 1.0 O C:HOH2108 2.3 28.6 1.0 O C:SER237 2.4 27.1 1.0 O C:SER239 2.5 25.6 1.0 OD2 C:ASP233 2.5 19.6 1.0 OD1 C:ASP233 2.6 19.9 1.0 CG C:ASP233 2.9 19.8 1.0 CG C:ASP235 3.2 22.9 1.0 OD2 C:ASP235 3.4 23.4 1.0 C C:SER237 3.5 27.0 1.0 C C:SER239 3.6 25.9 1.0 N C:SER237 4.1 26.3 1.0 O C:HOH2104 4.2 20.0 1.0 CA C:SER237 4.2 26.8 1.0 C C:SER238 4.3 27.3 1.0 N C:SER239 4.3 27.1 1.0 O C:ASP235 4.3 23.8 1.0 CB C:ASP233 4.4 18.9 1.0 N C:ASN240 4.4 24.8 1.0 N C:SER238 4.5 27.3 1.0 O C:HOH2103 4.5 28.7 1.0 CA C:ASN240 4.5 23.7 1.0 CB C:SER237 4.5 26.8 1.0 CB C:ASP235 4.5 22.2 1.0 C C:ASP235 4.5 23.5 1.0 O C:SER238 4.5 27.5 1.0 CA C:SER239 4.6 26.9 1.0 CA C:SER238 4.6 27.2 1.0 N C:ASP235 4.8 21.6 1.0 CA C:ASP235 4.8 22.5 1.0

Calcium binding site 2 out of 2 in the Structure of Globular Heads of M-Ficolin at Acidic pH


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Globular Heads of M-Ficolin at Acidic pH within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca400 b:24.9 occ:1.00 OD1 F:ASP235 2.2 23.1 1.0 O F:HOH2102 2.4 32.2 1.0 O F:SER237 2.4 27.8 1.0 O F:HOH2101 2.5 26.1 1.0 O F:SER239 2.5 25.8 1.0 OD2 F:ASP233 2.5 21.0 1.0 OD1 F:ASP233 2.6 20.0 1.0 CG F:ASP233 2.9 19.9 1.0 CG F:ASP235 3.1 23.1 1.0 OD2 F:ASP235 3.4 23.6 1.0 C F:SER237 3.5 27.4 1.0 C F:SER239 3.6 26.0 1.0 N F:SER237 4.1 26.6 1.0 CA F:SER237 4.2 27.2 1.0 C F:SER238 4.3 27.5 1.0 N F:SER239 4.3 27.0 1.0 O F:ASP235 4.3 23.0 1.0 CB F:ASP233 4.4 19.0 1.0 N F:ASN240 4.4 25.0 1.0 O F:HOH2099 4.4 30.5 1.0 N F:SER238 4.5 27.8 1.0 CA F:ASN240 4.5 24.2 1.0 CB F:ASP235 4.5 22.2 1.0 C F:ASP235 4.5 23.2 1.0 CB F:SER237 4.5 27.2 1.0 CA F:SER238 4.6 27.6 1.0 CA F:SER239 4.6 26.8 1.0 O F:SER238 4.6 27.8 1.0 N F:ASP235 4.7 21.5 1.0 CA F:ASP235 4.8 22.4 1.0

V.Garlatti, L.Martin, E.Gout, J.B.Reiser, T.Fujita, G.J.Arlaud, N.M.Thielens, C.Gaboriaud. Structural Basis For Innate Immune Sensing By M-Ficolin and Its Control By A pH-Dependent Conformational Switch. J. Biol. Chem. V. 282 35814 2007.
ISSN: ISSN 0021-9258
PubMed: 17897951
DOI: 10.1074/JBC.M705741200