Calcium in PDB 2n8r: Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr)

All present enzymatic activity of Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr):
3.4.24.65;

The structure of Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr) also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Calcium atom in the Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr) (pdb code 2n8r). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr), PDB code: 2n8r:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca303 b:0.0 occ:1.00 OE2 A:GLU201 2.3 0.0 1.0 O A:GLY178 2.3 0.0 1.0 O A:ILE180 2.3 0.0 1.0 OD1 A:ASP175 2.3 0.0 1.0 O A:GLY176 2.3 0.0 1.0 OD2 A:ASP198 2.3 0.0 1.0 H A:ASP175 3.3 0.0 1.0 HD23 A:LEU181 3.4 0.0 1.0 C A:ILE180 3.4 0.0 1.0 CG A:ASP198 3.5 0.0 1.0 C A:GLY178 3.5 0.0 1.0 CG A:ASP175 3.5 0.0 1.0 CD A:GLU201 3.5 0.0 1.0 C A:GLY176 3.5 0.0 1.0 N A:ILE180 3.7 0.0 1.0 H A:ILE180 3.8 0.0 1.0 HB A:ILE180 3.9 0.0 1.0 C A:GLY179 4.0 0.0 1.0 H A:GLY178 4.0 0.0 1.0 HG2 A:GLU201 4.0 0.0 1.0 HA A:LEU181 4.0 0.0 1.0 HB3 A:ASP198 4.0 0.0 1.0 N A:GLY178 4.0 0.0 1.0 CA A:ILE180 4.1 0.0 1.0 HB3 A:PHE174 4.1 0.0 1.0 C A:ASP175 4.1 0.0 1.0 HA A:LYS177 4.1 0.0 1.0 N A:GLY176 4.1 0.0 1.0 OD2 A:ASP175 4.2 0.0 1.0 HB2 A:ASP200 4.2 0.0 1.0 C A:LYS177 4.2 0.0 1.0 N A:ASP175 4.2 0.0 1.0 CB A:ASP198 4.2 0.0 1.0 O A:GLY179 4.3 0.0 1.0 CG A:GLU201 4.3 0.0 1.0 H A:GLY176 4.3 0.0 1.0 HA3 A:GLY179 4.3 0.0 1.0 O A:ASP175 4.3 0.0 1.0 CA A:GLY178 4.3 0.0 1.0 OD1 A:ASP198 4.4 0.0 1.0 HB2 A:ASP198 4.4 0.0 1.0 CD2 A:LEU181 4.4 0.0 1.0 HG3 A:GLU201 4.4 0.0 1.0 OE1 A:GLU201 4.4 0.0 1.0 N A:LYS177 4.4 0.0 1.0 CA A:GLY176 4.4 0.0 1.0 N A:GLY179 4.4 0.0 1.0 N A:LEU181 4.4 0.0 1.0 CA A:GLY179 4.5 0.0 1.0 CA A:LYS177 4.5 0.0 1.0 CA A:ASP175 4.5 0.0 1.0 HD21 A:LEU181 4.6 0.0 1.0 CB A:ILE180 4.6 0.0 1.0 CB A:ASP175 4.6 0.0 1.0 O A:LYS177 4.7 0.0 1.0 HA2 A:GLY178 4.7 0.0 1.0 CA A:LEU181 4.8 0.0 1.0 HD22 A:LEU181 4.8 0.0 1.0

Calcium binding site 2 out of 3 in the Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca304 b:0.0 occ:1.00 OD1 A:ASP194 2.3 0.0 1.0 O A:ASP158 2.3 0.0 1.0 O A:GLY190 2.3 0.0 1.0 O A:GLY192 2.3 0.0 1.0 CG A:ASP194 3.2 0.0 1.0 C A:ASP158 3.4 0.0 1.0 OD2 A:ASP194 3.4 0.0 1.0 C A:GLY192 3.5 0.0 1.0 C A:GLY190 3.5 0.0 1.0 O A:ALA157 3.7 0.0 1.0 H A:LEU160 3.8 0.0 1.0 HA A:ILE159 3.8 0.0 1.0 HA A:ASP158 3.9 0.0 1.0 HA A:ILE191 4.1 0.0 1.0 HH2 A:TRP109 4.1 0.0 1.0 HA3 A:GLY193 4.1 0.0 1.0 C A:ILE191 4.2 0.0 1.0 N A:GLY192 4.2 0.0 1.0 H A:ASP194 4.2 0.0 1.0 CA A:ASP158 4.3 0.0 1.0 N A:ILE159 4.3 0.0 1.0 O A:ILE191 4.3 0.0 1.0 H A:GLY192 4.4 0.0 1.0 CA A:GLY190 4.4 0.0 1.0 CA A:GLY192 4.4 0.0 1.0 N A:GLY190 4.5 0.0 1.0 N A:ILE191 4.5 0.0 1.0 CA A:ILE159 4.5 0.0 1.0 O A:GLY188 4.5 0.0 1.0 N A:GLY193 4.5 0.0 1.0 N A:ASP194 4.5 0.0 1.0 HA2 A:GLY190 4.5 0.0 1.0 CA A:ILE191 4.5 0.0 1.0 N A:LEU160 4.5 0.0 1.0 CB A:ASP194 4.6 0.0 1.0 HB2 A:LEU160 4.6 0.0 1.0 CA A:GLY193 4.6 0.0 1.0 H A:GLY190 4.7 0.0 1.0 C A:ALA157 4.7 0.0 1.0 C A:GLY193 4.7 0.0 1.0 HA3 A:GLY192 4.8 0.0 1.0 HA A:ASP194 4.8 0.0 1.0 C A:SER189 4.8 0.0 1.0 C A:ILE159 4.9 0.0 1.0 CA A:ASP194 4.9 0.0 1.0 N A:ASP158 5.0 0.0 1.0

Calcium binding site 3 out of 3 in the Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Productive Complex Between Mmp-12 and Synthetic Triple-Helical Collagen, Revealed Through Paramagnetic uc(Nmr) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca305 b:0.0 occ:1.00 OD2 A:ASP124 2.3 0.0 1.0 OD1 A:ASP124 2.3 0.0 1.0 OE2 A:GLU199 2.3 0.0 1.0 O A:GLU201 2.3 0.0 1.0 O A:GLU199 2.3 0.0 1.0 CG A:ASP124 2.7 0.0 1.0 HA A:PHE202 3.2 0.0 1.0 C A:GLU199 3.4 0.0 1.0 C A:GLU201 3.5 0.0 1.0 CD A:GLU199 3.5 0.0 1.0 HG1 A:THR122 3.5 0.0 1.0 HA A:GLU199 3.6 0.0 1.0 HD1 A:TRP203 3.6 0.0 1.0 HG3 A:GLU199 3.7 0.0 1.0 H A:TRP203 3.8 0.0 1.0 CA A:GLU199 4.0 0.0 1.0 OG1 A:THR122 4.1 0.0 1.0 CG A:GLU199 4.1 0.0 1.0 HD1 A:PHE202 4.1 0.0 1.0 CA A:PHE202 4.1 0.0 1.0 HD2 A:PRO123 4.2 0.0 1.0 N A:PHE202 4.2 0.0 1.0 CB A:ASP124 4.3 0.0 1.0 C A:ASP200 4.3 0.0 1.0 N A:GLU201 4.3 0.0 1.0 HG2 A:PRO123 4.4 0.0 1.0 HA A:ASP200 4.4 0.0 1.0 O A:ASP200 4.5 0.0 1.0 CD1 A:TRP203 4.5 0.0 1.0 N A:ASP200 4.5 0.0 1.0 OE1 A:GLU199 4.5 0.0 1.0 H A:ASP124 4.5 0.0 1.0 CA A:GLU201 4.5 0.0 1.0 H A:GLU201 4.5 0.0 1.0 CA A:ASP200 4.7 0.0 1.0 HB2 A:ASP124 4.7 0.0 1.0 HE1 A:TRP203 4.7 0.0 1.0 HH22 A:ARG165 4.7 0.0 1.0 CB A:GLU199 4.7 0.0 1.0 N A:TRP203 4.7 0.0 1.0 HB3 A:ASP124 4.7 0.0 1.0 HB2 A:PHE202 4.8 0.0 1.0 NE1 A:TRP203 5.0 0.0 1.0 CD1 A:PHE202 5.0 0.0 1.0

S.H.Prior, T.S.Byrne, D.Tokmina-Roszyk, G.B.Fields, S.R.Van Doren. Path to Collagenolysis: Collagen V Triple-Helix Model Bound Productively and in Encounters By Matrix Metalloproteinase-12. J.Biol.Chem. V. 291 7888 2016.
ISSN: ISSN 0021-9258
PubMed: 26887942
DOI: 10.1074/JBC.M115.703124