|
Atomistry » Calcium » PDB 2w3k-2whk » 2w3k | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Calcium » PDB 2w3k-2whk » 2w3k » |
Calcium in PDB 2w3k: Crystal Structure of Fxa in Complex with 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1Enzymatic activity of Crystal Structure of Fxa in Complex with 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1
All present enzymatic activity of Crystal Structure of Fxa in Complex with 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1:
3.4.21.6; Protein crystallography data
The structure of Crystal Structure of Fxa in Complex with 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1, PDB code: 2w3k
was solved by
E.Zhang,
I.Mochalkin,
A.Casimiro-Garcia,
C.A.Van Huis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2w3k:
The structure of Crystal Structure of Fxa in Complex with 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1 also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Crystal Structure of Fxa in Complex with 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1
(pdb code 2w3k). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of Fxa in Complex with 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1, PDB code: 2w3k: Calcium binding site 1 out of 1 in 2w3kGo back to Calcium Binding Sites List in 2w3k
Calcium binding site 1 out
of 1 in the Crystal Structure of Fxa in Complex with 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1
Mono view Stereo pair view
Reference:
C.A.Van Huis,
A.Casimiro-Garcia,
C.F.Bigge,
W.L.Cody,
D.A.Dudley,
K.J.Filipski,
R.J.Heemstra,
J.T.Kohrt,
R.J.J.Leadley,
L.S.Narasimhan,
T.Mcclanahan,
I.Mochalkin,
M.Pamment,
J.T.Peterson,
V.Sahasrabudhe,
R.P.Schaum,
J.J.Edmunds.
Exploration of 4,4-Disubstituted Pyrrolidine-1,2- Dicarboxamides As Potent, Orally Active Factor Xa Inhibitors with Extended Duration of Action. Bioorg.Med.Chem. V. 17 2501 2009.
Page generated: Sat Dec 12 03:55:11 2020
ISSN: ISSN 0968-0896 PubMed: 19231206 DOI: 10.1016/J.BMC.2009.01.063 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |