Calcium in PDB 2w4x: BTGH84 in Complex with Stz

All present enzymatic activity of BTGH84 in Complex with Stz:
3.2.1.52;

The structure of BTGH84 in Complex with Stz, PDB code: 2w4x was solved by Y.He, A.Bubb, C.Martinez-Fleites, G.J.Davies, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	83.05 / 2.42
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	186.990, 52.344, 84.267, 90.00, 99.30, 90.00
R / Rfree (%)	18.2 / 23.5

The binding sites of Calcium atom in the BTGH84 in Complex with Stz (pdb code 2w4x). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the BTGH84 in Complex with Stz, PDB code: 2w4x:

Calcium binding site 1 out of 1 in the BTGH84 in Complex with Stz


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of BTGH84 in Complex with Stz within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1592 b:77.6 occ:1.00 OE1 A:GLU61 2.4 29.6 1.0 O A:GLU32 2.4 31.2 1.0 OD1 A:ASP64 2.9 35.4 1.0 OD2 A:ASP64 3.1 32.3 1.0 CG A:ASP64 3.4 31.2 1.0 C A:GLU32 3.6 31.4 1.0 CD A:GLU61 3.6 27.5 1.0 CG A:GLU32 4.3 35.3 1.0 CG A:GLU61 4.5 26.0 1.0 CA A:ALA33 4.5 28.7 1.0 N A:ALA33 4.5 30.1 1.0 OE2 A:GLU61 4.5 28.0 1.0 CA A:GLU32 4.5 32.6 1.0 CB A:GLU61 4.5 25.1 1.0 OE2 A:GLU97 4.7 40.5 1.0 C A:ALA33 4.8 28.4 1.0 CB A:GLU32 4.8 33.2 1.0 CB A:ASP64 4.8 29.3 1.0 N A:GLU61 4.9 25.4 1.0

Y.He, C.Martinez-Fleites, A.Bubb, T.M.Gloster, G.J.Davies. Structural Insight Into the Mechanism of Streptozotocin Inhibition of O-Glcnacase. Carbohydr.Res. V. 344 627 2009.
ISSN: ISSN 0008-6215
PubMed: 19217614
DOI: 10.1016/J.CARRES.2008.12.007