Calcium in PDB 2w9d: Structure of Fab Fragment of the Icsm 18 - Anti-Prp Therapeutic Antibody at 1.57 A Resolution.

The structure of Structure of Fab Fragment of the Icsm 18 - Anti-Prp Therapeutic Antibody at 1.57 A Resolution., PDB code: 2w9d was solved by S.V.Antonyuk, C.R.Trevitt, R.W.Strange, G.S.Jackson, D.Sangar, M.Batchelor, S.Jones, T.Georgiou, S.Cooper, C.Fraser, A.Khalili-Shirazi, A.R.Clarke, S.S.Hasnain, J.Collinge, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.00 / 1.57
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.784, 84.710, 127.852, 90.00, 90.00, 90.00
R / Rfree (%)	18.4 / 21.7

The binding sites of Calcium atom in the Structure of Fab Fragment of the Icsm 18 - Anti-Prp Therapeutic Antibody at 1.57 A Resolution. (pdb code 2w9d). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Structure of Fab Fragment of the Icsm 18 - Anti-Prp Therapeutic Antibody at 1.57 A Resolution., PDB code: 2w9d:

Calcium binding site 1 out of 1 in the Structure of Fab Fragment of the Icsm 18 - Anti-Prp Therapeutic Antibody at 1.57 A Resolution.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Fab Fragment of the Icsm 18 - Anti-Prp Therapeutic Antibody at 1.57 A Resolution. within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca251 b:25.4 occ:0.50 O H:HOH2072 2.1 18.9 1.0 O H:HOH2125 2.2 29.5 1.0 O H:HOH2028 2.2 28.5 1.0 O H:HOH2067 2.3 29.4 1.0 O H:HOH2051 2.3 40.8 1.0 O H:HOH2126 2.8 44.3 1.0 OD1 H:ASN54 4.0 23.2 1.0 ND2 H:ASN54 4.0 21.6 1.0 O H:HOH2168 4.1 38.4 1.0 O H:PHE29 4.2 22.8 1.0 O H:HOH2084 4.2 22.7 1.0 OG H:SER77 4.3 30.5 1.0 O H:ASN27 4.3 23.8 1.0 O H:HOH2073 4.3 37.7 1.0 OD1 H:ASN27 4.4 23.8 1.0 O H:HOH2066 4.4 30.0 1.0 CG H:ASN54 4.5 24.2 1.0 CE2 H:TYR32 4.8 24.4 1.0

S.V.Antonyuk, C.R.Trevitt, R.W.Strange, G.S.Jackson, D.Sangar, M.Batchelor, S.Cooper, C.Fraser, S.Jones, T.Georgiou, A.Khalili-Shirazi, A.R.Clarke, S.S.Hasnain, J.Collinge. Crystal Structure of Human Prion Protein Bound to A Therapeutic Antibody. Proc.Natl.Acad.Sci.Usa V. 106 2554 2009.
ISSN: ISSN 0027-8424
PubMed: 19204296
DOI: 10.1073/PNAS.0809170106