Calcium in PDB 2wjs: Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain

The structure of Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain, PDB code: 2wjs was solved by F.Carafoli, N.J.Clout, E.Hohenester, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.80
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	138.829, 138.829, 73.895, 90.00, 90.00, 120.00
R / Rfree (%)	21.2 / 26.6

The binding sites of Calcium atom in the Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain (pdb code 2wjs). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain, PDB code: 2wjs:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca5001 b:49.0 occ:1.00 OD2 A:ASP2268 2.2 33.7 1.0 O A:VAL2206 2.4 23.7 1.0 O A:ILE2266 2.5 24.5 1.0 OD2 A:ASP2189 3.0 24.9 1.0 CG A:ASP2268 3.3 31.8 1.0 CD2 A:TYR2264 3.4 40.4 1.0 C A:VAL2206 3.4 23.6 1.0 C A:ILE2266 3.5 22.3 1.0 CB A:ASP2268 3.9 30.1 1.0 CB A:TYR2264 3.9 34.3 1.0 CG A:ASP2189 4.0 25.4 1.0 N A:ASP2268 4.0 27.0 1.0 N A:ILE2266 4.1 21.1 1.0 CA A:ILE2266 4.1 20.7 1.0 CG A:TYR2264 4.2 38.5 1.0 OD1 A:ASP2189 4.2 26.4 1.0 OD1 A:ASP2268 4.2 32.4 1.0 CB A:ILE2266 4.3 17.1 1.0 N A:GLY2207 4.3 24.5 1.0 CA A:VAL2206 4.3 22.4 1.0 CA A:GLY2207 4.3 23.6 1.0 CE2 A:TYR2264 4.4 43.5 1.0 CB A:VAL2206 4.5 21.8 1.0 CG2 A:ILE2266 4.5 16.2 1.0 CA A:ASP2268 4.6 29.5 1.0 N A:LEU2267 4.6 22.8 1.0 N A:THR2265 4.8 25.4 1.0 C A:LEU2267 4.8 24.4 1.0 CA A:LEU2267 4.9 23.2 1.0

Calcium binding site 2 out of 3 in the Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca5002 b:59.4 occ:1.00 O A:GLY2455 2.1 26.2 1.0 OD2 A:ASP2457 2.4 27.9 1.0 O A:LEU2400 2.6 21.4 1.0 OD2 A:ASP2383 2.7 28.0 1.0 C A:GLY2455 3.1 24.7 1.0 CA A:CA5003 3.3 49.5 1.0 CG A:ASP2457 3.5 26.3 1.0 N A:GLY2455 3.6 25.0 1.0 CA A:GLY2455 3.6 25.1 1.0 C A:LEU2400 3.7 20.1 1.0 CG A:ASP2383 3.8 29.4 1.0 CB A:ASN2453 4.0 27.7 1.0 OD1 A:ASN2453 4.0 27.2 1.0 OD1 A:ASP2383 4.1 29.7 1.0 N A:LEU2456 4.2 24.2 1.0 N A:ASP2457 4.2 21.8 1.0 CB A:LEU2400 4.2 19.2 1.0 CA A:LEU2400 4.2 19.9 1.0 OD1 A:ASP2457 4.3 26.5 1.0 CG A:ASN2453 4.3 26.7 1.0 CB A:ASP2457 4.5 23.5 1.0 CA A:LEU2456 4.6 22.7 1.0 N A:PHE2454 4.8 27.2 1.0 C A:PHE2454 4.8 25.5 1.0 N A:GLY2401 4.8 20.0 1.0 CA A:ASN2453 4.9 28.3 1.0 C A:LEU2456 4.9 21.3 1.0 C A:ASN2453 5.0 27.8 1.0 CA A:ASP2457 5.0 23.1 1.0

Calcium binding site 3 out of 3 in the Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of the LG1-3 Region of the Laminin ALPHA2 Chain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca5003 b:49.5 occ:1.00 OD1 A:ASP2383 2.7 29.7 1.0 OD2 A:ASP2383 3.3 28.0 1.0 CA A:CA5002 3.3 59.4 1.0 CG A:ASP2383 3.3 29.4 1.0 O A:LEU2400 3.4 21.4 1.0 OD1 A:ASN2453 3.6 27.2 1.0 OD2 A:ASP2457 3.7 27.9 1.0 CA A:GLY2401 4.1 19.5 1.0 C A:LEU2400 4.3 20.1 1.0 N A:GLY2401 4.6 20.0 1.0 CG A:ASN2453 4.7 26.7 1.0 CB A:LYS2382 4.7 30.6 1.0 CB A:ASP2383 4.7 26.1 1.0 CG A:ASP2457 4.8 26.3 1.0

F.Carafoli, N.J.Clout, E.Hohenester. Crystal Structure of the LG1-3 Region of the Laminin {Alpha}2 Chain. J.Biol.Chem. V. 284 22786 2009.
ISSN: ISSN 0021-9258
PubMed: 19553699
DOI: 10.1074/JBC.M109.026658