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Atomistry » Calcium » PDB 2wuv-2xc4 » 2xc4 » |
Calcium in PDB 2xc4: Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid InhibitorEnzymatic activity of Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor
All present enzymatic activity of Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor:
3.4.21.6; Protein crystallography data
The structure of Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor, PDB code: 2xc4
was solved by
D.W.Banner,
J.Benz,
D.Schlatter,
S.Thomi,
W.Haap,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2xc4:
The structure of Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor
(pdb code 2xc4). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor, PDB code: 2xc4: Calcium binding site 1 out of 1 in 2xc4Go back to Calcium Binding Sites List in 2xc4
Calcium binding site 1 out
of 1 in the Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor
Mono view Stereo pair view
Reference:
L.Anselm,
D.W.Banner,
J.Benz,
K.Groebke Zbinden,
J.Himber,
H.Hilpert,
W.Huber,
B.Kuhn,
J.L.Mary,
M.B.Otteneder,
N.Panday,
F.Ricklin,
M.Stahl,
S.Thomi,
W.Haap.
Discovery of A Factor Xa Inhibitor (3R,4R)-1-(2,2-Difluoro-Ethyl)-Pyrrolidine-3,4-Dicarboxylic Acid 3-[(5-Chloro-Pyridin-2-Yl)-Amide] 4-{[2-Fluoro-4-(2-Oxo-2H-Pyridin-1-Yl)-Phenyl]-Amide} As A Clinical Candidate. Bioorg.Med.Chem. V. 20 5313 2010.
Page generated: Fri Jul 12 19:03:09 2024
ISSN: ISSN 0968-0896 PubMed: 20650636 DOI: 10.1016/J.BMCL.2010.06.126 |
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