Atomistry » Calcium » PDB 2xc5-2xon » 2xef
Atomistry »
  Calcium »
    PDB 2xc5-2xon »
      2xef »

Calcium in PDB 2xef: Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8

Enzymatic activity of Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8

All present enzymatic activity of Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8:
3.4.17.21;

Protein crystallography data

The structure of Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8, PDB code: 2xef was solved by A.X.Zhang, R.P.Murelli, C.Barinka, J.Michel, A.Cocleaza, W.L.Jorgensen, J.Lubkowski, D.A.Spiegel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.59
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 101.844, 130.026, 158.741, 90.00, 90.00, 90.00
R / Rfree (%) 16.075 / 18.266

Other elements in 2xef:

The structure of Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8 also contains other interesting chemical elements:

Chlorine (Cl) 1 atom
Zinc (Zn) 2 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8 (pdb code 2xef). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8, PDB code: 2xef:

Calcium binding site 1 out of 1 in 2xef

Go back to Calcium Binding Sites List in 2xef
Calcium binding site 1 out of 1 in the Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Glutamate Carboxypeptidase II in Complex with Antibody-Recruiting Molecule Arm-P8 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1753

b:4.7
occ:1.00
 OE2 A:GLU436 2.3 17.8 1.0
O A:TYR272 2.3 15.6 1.0
O A:HOH2189 2.4 15.7 1.0
O A:THR269 2.4 14.7 1.0
OG1 A:THR269 2.5 15.6 1.0
OE2 A:GLU433 2.5 15.7 1.0
OE1 A:GLU433 2.5 14.4 1.0
CD A:GLU433 2.8 14.4 1.0
CB A:THR269 3.3 16.1 1.0
C A:THR269 3.3 15.8 1.0
CD A:GLU436 3.4 16.4 1.0
C A:TYR272 3.4 16.1 1.0
OE1 A:GLU436 3.9 15.8 1.0
CA A:THR269 4.0 15.8 1.0
N A:TYR272 4.0 15.1 1.0
CA A:PRO273 4.2 15.9 1.0
CB A:ASP266 4.2 15.8 1.0
N A:PRO270 4.2 15.1 1.0
N A:ALA274 4.3 16.1 1.0
N A:PRO273 4.3 15.7 1.0
CG A:GLU433 4.3 13.9 1.0
CA A:TYR272 4.4 16.5 1.0
N A:ASP266 4.4 14.3 1.0
C A:PRO273 4.4 15.9 1.0
N A:GLY271 4.5 15.1 1.0
CA A:PRO270 4.5 15.2 1.0
O A:ALA264 4.5 16.1 1.0
O A:ASP266 4.5 16.3 1.0
N A:THR269 4.6 15.6 1.0
CG2 A:THR269 4.7 16.4 1.0
CG A:GLU436 4.7 14.3 1.0
OD2 A:ASP266 4.7 18.1 1.0
C A:PRO270 4.7 15.9 1.0
CA A:ASP266 4.9 15.6 1.0
CB A:ALA274 4.9 16.5 1.0
CB A:GLU436 4.9 13.7 1.0
C A:GLY271 5.0 17.3 1.0

Reference:

A.X.Zhang, R.P.Murelli, C.Barinka, J.Michel, A.Cocleaza, W.L.Jorgensen, J.Lubkowski, D.A.Spiegel. A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed By Antibody-Recruiting Small Molecules. J.Am.Chem.Soc. V. 132 12711 2010.
ISSN: ISSN 0002-7863
PubMed: 20726553
DOI: 10.1021/JA104591M
Page generated: Fri Jul 12 19:04:00 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy