Calcium in PDB 2xo2: Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine

The structure of Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine, PDB code: 2xo2 was solved by M.Debela, L.Merkel, P.Goettig, N.Budisa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.09 / 2.80
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	152.708, 152.708, 33.603, 90.00, 90.00, 120.00
R / Rfree (%)	27.4 / 29.6

The structure of Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine also contains other interesting chemical elements:

Sodium	(Na)	1 atom
Chlorine	(Cl)	1 atom

The binding sites of Calcium atom in the Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine (pdb code 2xo2). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine, PDB code: 2xo2:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1327 b:61.3 occ:1.00 O4 A:SO41330 2.3 74.5 1.0 O A:LYS186 2.5 71.6 1.0 O A:GLY183 2.6 68.5 1.0 OE1 A:GLU228 2.7 64.7 1.0 O3 A:SO41330 2.7 74.4 1.0 O A:GLY188 2.7 71.3 1.0 S A:SO41330 2.9 74.5 1.0 OE2 A:GLU228 3.0 64.5 1.0 CD A:GLU228 3.2 64.5 1.0 O A:GLU184 3.3 69.4 1.0 C A:LYS186 3.4 71.5 1.0 O2 A:SO41330 3.5 74.3 1.0 C A:GLY183 3.6 68.5 1.0 N A:GLY188 3.6 71.6 1.0 C A:GLY188 3.7 71.2 1.0 N A:LYS186 3.8 70.9 1.0 C A:GLU184 3.8 69.5 1.0 CA A:LYS186 3.9 71.4 1.0 CA A:GLU184 4.0 69.4 1.0 CA A:GLY188 4.1 71.4 1.0 CB A:LYS186 4.1 71.6 1.0 N A:GLU184 4.2 69.0 1.0 O1 A:SO41330 4.3 74.6 1.0 N A:TRP187 4.5 71.7 1.0 CG A:GLU228 4.6 64.3 1.0 CA A:GLY183 4.7 68.2 1.0 O A:ALA182 4.7 67.0 1.0 C A:TRP187 4.7 71.8 1.0 N A:LEU185 4.8 69.8 1.0 N A:THR189 4.9 71.0 1.0 CA A:TRP187 4.9 71.9 1.0 C A:LEU185 5.0 70.5 1.0 CG A:LYS186 5.0 71.9 1.0

Calcium binding site 2 out of 2 in the Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Annexin V with Incorporated Methionine Analogue Azidohomoalanine within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1328 b:85.3 occ:1.00 O A:GLY30 2.2 77.2 1.0 OE2 A:GLU72 2.6 66.7 0.5 O A:AZH28 2.8 75.8 1.0 N A:GLY30 3.2 76.5 1.0 C A:GLY30 3.3 77.0 1.0 C A:LYS29 3.3 76.4 1.0 C A:AZH28 3.5 75.3 1.0 CD A:GLU72 3.5 66.7 0.5 N A:LYS29 3.6 75.8 1.0 O A:GLY32 3.6 75.6 1.0 CA A:LYS29 3.7 76.1 0.5 OE1 A:GLU72 3.7 66.7 0.5 CA A:GLY30 3.8 76.9 1.0 O A:LYS29 3.9 76.3 1.0 O2 A:SO41331 4.1 97.3 1.0 N A:LEU31 4.5 77.1 1.0 N A:GLY32 4.5 76.7 1.0 CA A:AZH28 4.6 74.8 1.0 C A:GLY32 4.6 75.7 1.0 CG A:GLU72 4.7 66.7 0.5 OG1 A:THR33 4.8 74.4 1.0 CA A:LEU31 4.8 77.1 1.0

M.Debela, L.Merkel, P.Goettig, N.Budisa. Non-Canonical Amino Acids For Click Chemistry Reactions Incorporated in Human Annexin V To Be Published.