Calcium in PDB 2xvt: Structure of the Extracellular Domain of Human RAMP2

The structure of Structure of the Extracellular Domain of Human RAMP2, PDB code: 2xvt was solved by A.Quigley, A.C.W.Pike, N.Burgess-Brown, T.Krojer, L.Shrestha, S.Goubin, J.Kim, S.Das, J.R.C.Muniz, P.Canning, A.Chaikuad, M.Vollmar, F.Von Delft, C.H.Arrowsmith, J.Weigelt, A.M.Edwards, C.Bountra, A.J.Barr, E.P.Carpenter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	64.71 / 2.05
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.759, 90.984, 92.056, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 24.6

The binding sites of Calcium atom in the Structure of the Extracellular Domain of Human RAMP2 (pdb code 2xvt). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Structure of the Extracellular Domain of Human RAMP2, PDB code: 2xvt:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Structure of the Extracellular Domain of Human RAMP2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the Extracellular Domain of Human RAMP2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca1137 b:35.4 occ:1.00 O F:HOH2028 2.1 32.6 1.0 OE2 C:GLU105 2.3 32.5 1.0 OE2 C:GLU101 2.3 29.4 1.0 O F:GLU105 2.4 31.9 1.0 OD1 F:ASP108 2.4 35.9 1.0 O C:HOH2035 2.9 38.0 1.0 CD C:GLU101 3.5 32.3 1.0 C F:GLU105 3.5 27.6 1.0 CD C:GLU105 3.5 48.9 1.0 CG F:ASP108 3.7 42.2 1.0 O C:HOH2033 4.2 33.0 1.0 CG C:GLU101 4.2 23.4 1.0 OE1 C:GLU105 4.3 38.2 1.0 CA F:GLU105 4.3 27.6 1.0 OD2 F:ASP108 4.4 42.2 1.0 OE1 C:GLU101 4.5 28.4 1.0 N F:LEU106 4.5 29.2 1.0 CG C:GLU105 4.5 36.8 1.0 CA F:ASP108 4.6 29.4 1.0 O F:LEU106 4.6 32.4 1.0 N F:ASP108 4.6 28.2 1.0 CB F:GLU105 4.6 27.2 1.0 CA F:LEU106 4.6 31.4 1.0 CB F:ASP108 4.7 30.9 1.0 C F:LEU106 4.7 31.1 1.0

Calcium binding site 2 out of 3 in the Structure of the Extracellular Domain of Human RAMP2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the Extracellular Domain of Human RAMP2 within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca1137 b:31.2 occ:1.00 OE2 F:GLU105 2.2 32.4 1.0 O C:HOH2038 2.3 34.5 1.0 O F:HOH2025 2.3 27.2 1.0 OE2 F:GLU101 2.4 27.0 1.0 OD1 C:ASP108 2.5 44.2 1.0 O C:GLU105 2.5 28.4 1.0 CD F:GLU105 3.2 47.4 1.0 CD F:GLU101 3.5 26.8 1.0 C C:GLU105 3.5 29.3 1.0 OE1 F:GLU105 3.5 30.9 1.0 CG C:ASP108 3.7 48.7 1.0 CG F:GLU101 4.2 23.7 1.0 OD2 C:ASP108 4.2 49.3 1.0 CA C:GLU105 4.3 29.5 1.0 O F:HOH2022 4.4 34.2 1.0 OE1 F:GLU101 4.4 21.6 1.0 N C:LEU106 4.5 28.4 1.0 CG F:GLU105 4.6 31.3 1.0 CB C:GLU105 4.6 30.7 1.0 CA C:LEU106 4.6 32.6 1.0 O F:HOH2032 4.6 36.6 1.0 O C:LEU106 4.7 33.0 1.0 N C:ASP108 4.7 33.8 1.0 CA C:ASP108 4.8 33.5 1.0 O C:HOH2036 4.8 30.1 1.0 C C:LEU106 4.8 33.6 1.0 CB C:ASP108 4.8 36.3 1.0

Calcium binding site 3 out of 3 in the Structure of the Extracellular Domain of Human RAMP2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of the Extracellular Domain of Human RAMP2 within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca1138 b:37.6 occ:0.75 O F:HOH2026 2.1 34.2 1.0 O F:ASP108 2.3 25.3 1.0 O F:HOH2029 2.3 31.0 1.0 O B:HOH2021 2.4 30.9 1.0 O B:HOH2022 2.5 37.6 1.0 C F:ASP108 3.5 24.2 1.0 CB F:ASP108 3.8 30.9 1.0 O C:HOH2042 4.3 34.0 1.0 CA F:ASP108 4.3 29.4 1.0 O D:HOH2023 4.4 24.9 1.0 N F:LEU109 4.5 23.0 1.0 OE1 B:GLU101 4.5 24.4 1.0 O F:HOH2027 4.6 31.9 1.0 NE D:ARG91 4.6 29.7 1.0 CA F:LEU109 4.6 22.4 1.0 OD1 B:ASP98 4.7 36.2 1.0 O B:HOH2026 4.7 21.8 1.0

A.Quigley, A.C.W.Pike, N.Burgess-Brown, T.Krojer, L.Shrestha, S.Goubin, J.Kim, S.Das, J.R.C.Muniz, P.Canning, A.Chaikuad, M.Vollmar, F.Von Delft, C.H.Arrowsmith, J.Weigelt, A.M.Edwards, C.Bountra, A.J.Barr, E.P.Carpenter. Structure of the Extracellular Domain of Human RAMP2 To Be Published.