|
Atomistry » Calcium » PDB 2y6j-2yhy » 2y7x | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Calcium » PDB 2y6j-2yhy » 2y7x » |
Calcium in PDB 2y7x: The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 MotifsEnzymatic activity of The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs
All present enzymatic activity of The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs:
3.4.21.6; Protein crystallography data
The structure of The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs, PDB code: 2y7x
was solved by
N.S.Watson,
C.Adams,
D.Belton,
D.Brown,
C.L.Burns-Kurtis,
L.Chaudry,
C.Chan,
M.A.Convery,
D.E.Davies,
A.M.Exall,
J.D.Harling,
W.R.Irving,
S.Irvine,
S.Kleanthous,
I.M.Mclay,
A.J.Pateman,
A.N.Patikis,
T.J.Roethka,
S.Senger,
G.J.Stelman,
J.R.Toomey,
R.I.West,
C.Whittaker,
P.Zhou,
R.J.Young,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2y7x:
The structure of The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs
(pdb code 2y7x). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs, PDB code: 2y7x: Calcium binding site 1 out of 1 in 2y7xGo back to Calcium Binding Sites List in 2y7x
Calcium binding site 1 out
of 1 in the The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs
Mono view Stereo pair view
Reference:
N.S.Watson,
C.Adams,
D.Belton,
D.Brown,
C.L.Burns-Kurtis,
L.Chaudry,
C.Chan,
M.A.Convery,
D.E.Davies,
A.M.Exall,
J.D.Harling,
S.Irvine,
W.R.Irving,
S.Kleanthous,
I.M.Mclay,
A.J.Pateman,
A.N.Patikis,
T.J.Roethke,
S.Senger,
G.J.Stelman,
J.R.Toomey,
R.I.West,
C.Whittaker,
P.Zhou,
R.J.Young.
The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs. Bioorg.Med.Chem.Lett. V. 21 1588 2011.
Page generated: Sat Dec 12 03:59:57 2020
ISSN: ISSN 0960-894X PubMed: 21349711 DOI: 10.1016/J.BMCL.2011.01.129 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |