Atomistry » Calcium » PDB 2y6j-2yhy » 2yhw
Atomistry »
  Calcium »
    PDB 2y6j-2yhy »
      2yhw »

Calcium in PDB 2yhw: High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling.

Enzymatic activity of High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling.

All present enzymatic activity of High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling.:
2.7.1.60;

Protein crystallography data

The structure of High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling., PDB code: 2yhw was solved by J.Martinez, L.D.Nguyen, E.Tauberger, S.Hinderlich, R.Zimmer, E.Tauberger, W.Reutter, W.Saenger, H.Fan, S.Moniot, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.37 / 1.64
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 90.730, 90.730, 100.780, 90.00, 90.00, 90.00
R / Rfree (%) 14.82 / 17.019

Other elements in 2yhw:

The structure of High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling. also contains other interesting chemical elements:

Chlorine (Cl) 1 atom
Zinc (Zn) 1 atom

Calcium Binding Sites:

The binding sites of Calcium atom in the High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling. (pdb code 2yhw). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling., PDB code: 2yhw:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in 2yhw

Go back to Calcium Binding Sites List in 2yhw
Calcium binding site 1 out of 2 in the High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1724

b:13.0
occ:0.50
 CA A:CA1724 0.0 13.0 0.5
CA A:CA1724 1.4 23.5 0.3
O A:GLY548 2.4 11.9 1.0
OD1 A:ASN516 2.5 13.3 1.0
O A:ALA565 2.6 12.4 1.0
O A:HOH2108 2.6 9.8 1.0
OD1 A:ASN519 3.3 14.6 1.0
C A:ALA565 3.4 12.2 1.0
CG A:ASN516 3.4 12.8 1.0
C A:GLY548 3.5 11.5 1.0
CB A:ALA565 3.8 13.3 1.0
N A:GLY548 3.9 12.9 1.0
O A:HOH2067 3.9 19.6 1.0
O A:ALA564 3.9 14.9 1.0
CG A:ASN519 4.0 15.9 1.0
N A:ASN519 4.0 12.5 1.0
CA A:GLY548 4.1 13.6 1.0
CA A:ALA565 4.1 12.2 1.0
ND2 A:ASN516 4.1 11.4 1.0
N A:GLU566 4.2 11.3 1.0
CA A:GLY518 4.2 12.2 1.0
CB A:ASN516 4.3 11.9 1.0
C A:GLY518 4.3 12.0 1.0
N A:GLY549 4.5 11.8 1.0
CA A:GLU566 4.5 11.2 1.0
ND2 A:ASN519 4.5 14.0 1.0
N A:GLY518 4.5 11.7 1.0
OE2 A:GLU566 4.7 14.8 1.0
CA A:GLY549 4.8 12.3 1.0
CD A:GLU566 4.8 14.3 1.0
CA A:ASN519 4.8 11.2 1.0
O4 A:BM31718 4.8 12.3 1.0
O A:HOH2111 4.9 13.3 1.0
C A:ALA564 4.9 14.0 1.0
CB A:ASN519 4.9 11.9 1.0
CG A:GLU566 4.9 13.4 1.0
N A:ALA565 5.0 12.0 1.0

Calcium binding site 2 out of 2 in 2yhw

Go back to Calcium Binding Sites List in 2yhw
Calcium binding site 2 out of 2 in the High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of High-Resolution Crystal Structures of N-Acetylmannosamine Kinase: Insights About Substrate Specificity, Activity and Inhibitor Modelling. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1724

b:23.5
occ:0.35
 CA A:CA1724 0.0 23.5 0.3
CA A:CA1724 1.4 13.0 0.5
O A:ALA564 2.8 14.9 1.0
O A:ALA565 3.1 12.4 1.0
O A:HOH2067 3.1 19.6 1.0
OD1 A:ASN516 3.1 13.3 1.0
OD1 A:ASN519 3.1 14.6 1.0
C A:ALA565 3.3 12.2 1.0
O A:GLY548 3.5 11.9 1.0
CG A:ASN516 3.6 12.8 1.0
O A:HOH2111 3.6 13.3 1.0
O A:HOH2108 3.6 9.8 1.0
CB A:ALA565 3.7 13.3 1.0
CG A:ASN519 3.7 15.9 1.0
ND2 A:ASN519 3.9 14.0 1.0
CA A:ALA565 3.9 12.2 1.0
N A:GLU566 3.9 11.3 1.0
C A:ALA564 4.0 14.0 1.0
CB A:ASN516 4.1 11.9 1.0
ND2 A:ASN516 4.3 11.4 1.0
N A:ALA565 4.4 12.0 1.0
CG A:GLU566 4.4 13.4 1.0
OE2 A:GLU566 4.4 14.8 1.0
CA A:GLU566 4.5 11.2 1.0
C A:GLY548 4.5 11.5 1.0
O A:HOH2068 4.6 9.3 1.0
CD A:GLU566 4.6 14.3 1.0
N A:ASN519 4.7 12.5 1.0
CB A:ASN519 4.9 11.9 1.0
O A:HOH2110 4.9 10.3 1.0

Reference:

J.Martinez, L.D.Nguyen, E.Tauberger, S.Hinderlich, W.Reutter, H.Fan, W.Saenger, S.Moniot. Crystal Structures of N-Acetylmannosamine Kinase Provide Insights Into Enzyme Specificity and Inhibition J.Biol.Chem. V. 287 13656 2012.
ISSN: ISSN 0021-9258
PubMed: 22343627
DOI: 10.1074/JBC.M111.318170
Page generated: Fri Jul 12 19:30:59 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy