Calcium in PDB 3dd4: Structural Basis of KCHIP4A Modulation of KV4.3 Slow Inactivation

The structure of Structural Basis of KCHIP4A Modulation of KV4.3 Slow Inactivation, PDB code: 3dd4 was solved by J.Chai, H.Wang, K.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.00
Space group	I 41
Cell size a, b, c (Å), α, β, γ (°)	96.300, 96.300, 71.100, 90.00, 90.00, 90.00
R / Rfree (%)	23.9 / 29.9

The binding sites of Calcium atom in the Structural Basis of KCHIP4A Modulation of KV4.3 Slow Inactivation (pdb code 3dd4). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structural Basis of KCHIP4A Modulation of KV4.3 Slow Inactivation, PDB code: 3dd4:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structural Basis of KCHIP4A Modulation of KV4.3 Slow Inactivation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structural Basis of KCHIP4A Modulation of KV4.3 Slow Inactivation within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca404 b:94.4 occ:1.00 ND2 A:ASN198 2.0 0.0 1.0 O A:VAL202 2.2 75.0 1.0 OE1 A:GLU207 2.4 97.5 1.0 CG A:ASN198 2.7 0.4 1.0 OD1 A:ASN198 2.7 1.0 1.0 OD1 A:ASP196 2.9 88.2 1.0 OD2 A:ASP200 2.9 87.9 1.0 CD A:GLU207 3.1 96.8 1.0 OD1 A:ASP200 3.2 87.6 1.0 OE2 A:GLU207 3.2 98.6 1.0 CG A:ASP200 3.3 89.7 1.0 C A:VAL202 3.4 77.1 1.0 CG A:ASP196 4.0 94.5 1.0 CB A:ASN198 4.1 0.4 1.0 CA A:VAL203 4.2 85.7 1.0 N A:VAL203 4.2 87.0 1.0 CG2 A:VAL202 4.3 71.9 1.0 N A:ASN198 4.4 0.3 1.0 N A:VAL202 4.4 80.9 1.0 CA A:VAL202 4.4 75.2 1.0 CG A:GLU207 4.5 94.1 1.0 N A:ASP200 4.6 0.9 1.0 CA A:ASP196 4.6 0.5 1.0 CA A:ASN198 4.6 0.7 1.0 CB A:ASP200 4.7 95.7 1.0 N A:LYS197 4.7 0.1 1.0 C A:ASN198 4.7 0.0 1.0 N A:LYS199 4.7 0.1 1.0 OD2 A:ASP196 4.8 89.9 1.0 CB A:ASP196 4.8 0.6 1.0 C A:ASP196 4.9 0.7 1.0 CB A:VAL202 5.0 73.0 1.0

Calcium binding site 2 out of 2 in the Structural Basis of KCHIP4A Modulation of KV4.3 Slow Inactivation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structural Basis of KCHIP4A Modulation of KV4.3 Slow Inactivation within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca405 b:71.4 occ:1.00 O A:TYR154 2.2 85.7 1.0 OD1 A:ASN150 2.3 99.6 1.0 OE2 A:GLU159 2.3 62.7 1.0 OD1 A:ASP148 2.6 99.0 1.0 OE1 A:GLU159 2.8 60.5 1.0 CD A:GLU159 2.9 65.0 1.0 OD1 A:ASP152 2.9 86.6 1.0 C A:TYR154 3.0 85.1 1.0 OD2 A:ASP152 3.3 87.0 1.0 CG A:ASP152 3.3 84.4 1.0 CG A:ASN150 3.4 95.8 1.0 CG A:ASP148 3.7 96.7 1.0 N A:ILE155 3.8 73.8 1.0 CA A:ASP148 3.8 61.7 1.0 CA A:ILE155 3.9 82.3 1.0 N A:TYR154 3.9 78.9 1.0 CA A:TYR154 3.9 87.3 1.0 ND2 A:ASN150 4.0 0.0 1.0 C A:ASP148 4.1 59.0 1.0 CB A:ASP148 4.2 95.6 1.0 CB A:TYR154 4.2 82.7 1.0 N A:ASP152 4.3 74.9 1.0 CG A:GLU159 4.4 70.5 1.0 N A:THR156 4.5 84.3 1.0 O A:ASP148 4.5 56.9 1.0 N A:LYS151 4.5 67.6 1.0 N A:ILE149 4.5 55.9 1.0 CB A:ASN150 4.6 89.4 1.0 CB A:ASP152 4.6 81.5 1.0 N A:ASN150 4.7 78.0 1.0 C A:ILE155 4.7 77.8 1.0 OD2 A:ASP148 4.7 97.1 1.0 N A:GLY153 4.8 65.2 1.0 O A:TYR147 4.8 66.4 1.0 CA A:ASP152 5.0 74.1 1.0 CB A:GLU159 5.0 79.6 1.0

P.Liang, H.Wang, H.Chen, Y.Cui, L.Gu, J.Chai, K.Wang. Structural Insights Into KCHIP4A Modulation of KV4.3 Inactivation. J.Biol.Chem. V. 284 4960 2009.
ISSN: ISSN 0021-9258
PubMed: 19109250
DOI: 10.1074/JBC.M807704200