Calcium in PDB 3dvj: Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex

The structure of Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex, PDB code: 3dvj was solved by E.Y.Kim, C.H.Rumpf, Y.Fujiwara, E.S.Cooley, F.Van Petegem, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.80
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	40.321, 40.321, 348.558, 90.00, 90.00, 120.00
R / Rfree (%)	24.8 / 29.8

The binding sites of Calcium atom in the Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex (pdb code 3dvj). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex, PDB code: 3dvj:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca501 b:42.3 occ:1.00 O A:THR26 2.1 31.1 1.0 OD1 A:ASP22 2.2 47.7 1.0 OE2 A:GLU31 2.4 27.7 1.0 OD1 A:ASP24 2.4 38.4 1.0 OE1 A:GLU31 2.5 24.4 1.0 OD1 A:ASP20 2.7 37.0 1.0 CD A:GLU31 2.8 25.9 1.0 CG A:ASP22 3.1 45.0 1.0 OD2 A:ASP22 3.3 43.9 1.0 C A:THR26 3.3 32.8 1.0 CG A:ASP24 3.4 37.7 1.0 OD2 A:ASP24 3.7 38.8 1.0 CG A:ASP20 3.8 37.9 1.0 OG1 A:THR26 4.1 34.4 1.0 N A:ILE27 4.2 33.1 1.0 CA A:ILE27 4.2 28.4 1.0 CG2 A:THR28 4.2 24.1 1.0 CG A:GLU31 4.2 25.1 1.0 N A:THR26 4.3 34.9 1.0 CA A:THR26 4.3 32.9 1.0 N A:THR28 4.4 25.1 1.0 CA A:ASP20 4.4 38.5 1.0 CB A:ASP22 4.5 43.8 1.0 N A:ASP22 4.5 44.5 1.0 C A:ASP20 4.5 39.2 1.0 CB A:ASP24 4.6 36.1 1.0 OD2 A:ASP20 4.6 38.5 1.0 N A:ASP24 4.6 38.8 1.0 CB A:ASP20 4.7 36.5 1.0 N A:LYS21 4.8 39.7 1.0 C A:ILE27 4.8 28.8 1.0 CB A:THR26 4.8 31.8 1.0 O A:ASP20 4.9 39.5 1.0 CA A:ASP22 4.9 43.5 1.0 N A:GLY23 5.0 41.9 1.0

Calcium binding site 2 out of 4 in the Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca502 b:46.0 occ:1.00 O A:THR62 2.2 43.1 1.0 OD1 A:ASP58 2.3 61.8 1.0 OD2 A:ASP56 2.4 47.1 1.0 OE1 A:GLU67 2.4 51.9 1.0 OE2 A:GLU67 2.5 50.7 1.0 OD1 A:ASN60 2.5 46.1 1.0 CD A:GLU67 2.8 48.6 1.0 CG A:ASN60 3.2 43.7 1.0 CG A:ASP58 3.2 60.2 1.0 OD2 A:ASP58 3.4 60.4 1.0 ND2 A:ASN60 3.4 42.6 1.0 C A:THR62 3.4 42.0 1.0 CG A:ASP56 3.7 49.5 1.0 N A:THR62 4.1 42.1 1.0 CG A:GLU67 4.2 46.6 1.0 CA A:ILE63 4.3 43.7 1.0 CA A:ASP56 4.3 57.5 1.0 N A:ASP64 4.3 45.3 1.0 N A:ILE63 4.3 43.7 1.0 CA A:THR62 4.4 40.3 1.0 CB A:ASN60 4.4 44.1 1.0 OD2 A:ASP64 4.4 47.2 1.0 N A:ASN60 4.5 47.7 1.0 OG1 A:THR62 4.5 36.7 1.0 CB A:ASP58 4.5 56.6 1.0 CB A:ASP56 4.5 52.4 1.0 N A:ASP58 4.5 52.3 1.0 OD1 A:ASP56 4.5 47.7 1.0 CG A:ASP64 4.5 45.8 1.0 C A:ILE63 4.7 45.5 1.0 C A:ASP56 4.7 58.1 1.0 OD1 A:ASP64 4.8 46.9 1.0 N A:GLY59 4.8 52.4 1.0 N A:GLY61 4.8 43.8 1.0 CA A:ASP58 4.9 54.8 1.0 CA A:ASN60 4.9 45.6 1.0 N A:ALA57 5.0 57.4 1.0 CB A:GLU67 5.0 46.0 1.0 C A:ASN60 5.0 45.5 1.0

Calcium binding site 3 out of 4 in the Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca503 b:32.4 occ:1.00 OD1 A:ASP95 2.3 28.4 1.0 OD1 A:ASP93 2.3 33.9 1.0 OE2 A:GLU104 2.3 35.7 1.0 OD1 A:ASN97 2.3 30.6 1.0 O A:TYR99 2.4 25.6 1.0 OE1 A:GLU104 2.7 34.4 1.0 CD A:GLU104 2.8 34.4 1.0 CG A:ASP95 3.2 26.9 1.0 CG A:ASN97 3.4 30.3 1.0 OD2 A:ASP95 3.4 26.7 1.0 CG A:ASP93 3.5 32.0 1.0 C A:TYR99 3.6 25.1 1.0 ND2 A:ASN97 4.1 29.0 1.0 N A:ASN97 4.1 29.8 1.0 CA A:ASP93 4.2 32.3 1.0 N A:TYR99 4.3 25.4 1.0 OD2 A:ASP93 4.3 34.2 1.0 N A:ASP95 4.3 31.6 1.0 C A:ASP93 4.3 32.2 1.0 CG A:GLU104 4.3 31.2 1.0 CB A:ASP93 4.4 29.3 1.0 CB A:ASN97 4.4 27.9 1.0 CA A:ILE100 4.5 25.9 1.0 N A:LYS94 4.5 33.0 1.0 N A:ILE100 4.5 27.8 1.0 CB A:ASP95 4.5 27.6 1.0 N A:GLY96 4.5 28.0 1.0 CA A:TYR99 4.6 21.0 1.0 N A:SER101 4.7 29.9 1.0 CA A:ASN97 4.7 27.5 1.0 N A:GLY98 4.7 29.7 1.0 O A:ASP93 4.8 30.2 1.0 CA A:ASP95 4.8 28.5 1.0 C A:ASP95 4.9 29.4 1.0 O A:HOH508 4.9 24.1 1.0 C A:ASN97 5.0 28.3 1.0 CB A:TYR99 5.0 18.6 1.0

Calcium binding site 4 out of 4 in the Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of CA2+/Cam-CAV2.2 Iq Domain (Without Cloning Artifact, Hm to Tv) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca504 b:30.2 occ:1.00 O A:GLN135 2.3 25.2 1.0 OD1 A:ASP129 2.4 16.5 1.0 OD1 A:ASP131 2.4 26.3 1.0 OE1 A:GLU140 2.4 25.6 1.0 OD1 A:ASP133 2.4 24.0 1.0 OE2 A:GLU140 2.5 19.6 1.0 CD A:GLU140 2.8 24.4 1.0 CG A:ASP131 3.2 24.2 1.0 CG A:ASP133 3.3 25.5 1.0 OD2 A:ASP131 3.4 20.4 1.0 C A:GLN135 3.4 23.9 1.0 CG A:ASP129 3.5 23.9 1.0 OD2 A:ASP133 3.7 26.7 1.0 N A:GLN135 4.2 23.0 1.0 N A:ASP133 4.2 19.4 1.0 OD2 A:ASP129 4.2 23.0 1.0 CG A:GLU140 4.3 24.0 1.0 N A:ASP131 4.3 19.6 1.0 N A:VAL136 4.3 24.2 1.0 CA A:VAL136 4.3 27.2 1.0 N A:ASN137 4.4 30.1 1.0 CA A:GLN135 4.4 21.6 1.0 CB A:ASP133 4.4 19.9 1.0 CA A:ASP129 4.4 20.2 1.0 N A:ILE130 4.4 25.4 1.0 N A:GLY132 4.4 20.0 1.0 CB A:ASP129 4.5 20.0 1.0 CB A:ASP131 4.5 21.1 1.0 ND2 A:ASN137 4.6 34.8 1.0 N A:GLY134 4.7 16.8 1.0 C A:VAL136 4.8 31.1 1.0 CA A:ASP133 4.8 18.5 1.0 CA A:ASP131 4.8 19.6 1.0 C A:ASP129 4.9 23.0 1.0 CG A:ASN137 4.9 32.6 1.0 C A:ASP131 5.0 21.7 1.0 C A:ASP133 5.0 17.9 1.0 CB A:GLN135 5.0 19.1 1.0 CB A:GLU140 5.0 22.6 1.0

E.Y.Kim, C.H.Rumpf, Y.Fujiwara, E.S.Cooley, F.Van Petegem, D.L.Minor. Structures of Ca(V)2 Ca(2+)/Cam-Iq Domain Complexes Reveal Binding Modes That Underlie Calcium-Dependent Inactivation and Facilitation. Structure V. 16 1455 2008.
ISSN: ISSN 0969-2126
PubMed: 18940602
DOI: 10.1016/J.STR.2008.07.010