Calcium in PDB 3kxz: The Complex Crystal Structure of Lck with A Probe Molecule W259

All present enzymatic activity of The Complex Crystal Structure of Lck with A Probe Molecule W259:
2.7.10.2;

The structure of The Complex Crystal Structure of Lck with A Probe Molecule W259, PDB code: 3kxz was solved by Z.B.Xu, F.J.Moy, K.Kelleher, L.Mosyak, Protein Structure Factory (Psf), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.60 / 2.37
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	42.012, 73.784, 84.717, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 26.1

The binding sites of Calcium atom in the The Complex Crystal Structure of Lck with A Probe Molecule W259 (pdb code 3kxz). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the The Complex Crystal Structure of Lck with A Probe Molecule W259, PDB code: 3kxz:

Calcium binding site 1 out of 1 in the The Complex Crystal Structure of Lck with A Probe Molecule W259


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of The Complex Crystal Structure of Lck with A Probe Molecule W259 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca3 b:63.2 occ:1.00 OG A:SER332 3.0 37.4 1.0 N A:SER332 3.5 40.8 1.0 CD A:PRO331 3.7 28.9 1.0 CB A:SER332 3.8 36.5 1.0 O A:HOH21 3.8 58.3 1.0 CB A:PRO331 3.8 34.2 1.0 CG A:PRO331 4.0 34.1 1.0 N A:PRO331 4.1 32.7 1.0 CB A:THR330 4.2 30.6 1.0 CA A:SER332 4.2 37.5 1.0 OG1 A:THR330 4.3 26.6 1.0 CA A:PRO331 4.4 33.4 1.0 C A:PRO331 4.4 38.6 1.0 C A:THR330 4.7 33.4 1.0

F.J.Moy, A.Lee, L.K.Gavrin, Z.B.Xu, A.Sievers, E.Kieras, W.Stochaj, L.Mosyak, J.Mckew, D.H.Tsao. Novel Synthesis and Structural Characterization of A High-Affinity Paramagnetic Kinase Probe For the Identification of Non-Atp Site Binders By Nuclear Magnetic Resonance. J.Med.Chem. V. 53 1238 2010.
ISSN: ISSN 0022-2623
PubMed: 20038108
DOI: 10.1021/JM901525B