Calcium in PDB 3ltl: Crystal Structure of Human BIG1 SEC7 Domain

The structure of Crystal Structure of Human BIG1 SEC7 Domain, PDB code: 3ltl was solved by P.C.Simister, A.Joubert, J.Cherfils, V.Biou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.61 / 2.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	64.451, 36.867, 85.848, 90.00, 90.06, 90.00
R / Rfree (%)	17.5 / 23.6

The binding sites of Calcium atom in the Crystal Structure of Human BIG1 SEC7 Domain (pdb code 3ltl). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Human BIG1 SEC7 Domain, PDB code: 3ltl:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Human BIG1 SEC7 Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Human BIG1 SEC7 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1 b:74.5 occ:1.00 O A:PHE788 3.3 30.6 1.0 O A:LEU785 3.4 40.8 1.0 N A:LEU790 3.8 31.0 1.0 CB A:LEU785 3.9 29.9 1.0 CA A:ARG789 4.0 29.3 1.0 CG A:MET884 4.1 53.1 1.0 C A:LEU785 4.3 33.7 1.0 C A:PHE788 4.4 27.9 1.0 C A:ARG789 4.4 24.8 1.0 CA A:LEU785 4.5 32.1 1.0 CD2 A:LEU785 4.5 33.9 1.0 CG A:LEU785 4.6 33.6 1.0 CB A:LEU790 4.7 36.7 1.0 N A:ARG789 4.7 27.5 1.0 CG2 A:ILE882 4.7 31.1 1.0 CG A:LEU790 4.8 43.1 1.0 CA A:LEU790 4.8 27.7 1.0 CD1 A:LEU785 4.9 38.0 1.0 CG A:ARG789 4.9 39.7 1.0 CB A:ARG789 5.0 26.0 1.0 C A:SER883 5.0 41.3 1.0 O A:SER883 5.0 46.9 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Human BIG1 SEC7 Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Human BIG1 SEC7 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2 b:63.5 occ:1.00 O A:PHE784 2.7 26.6 1.0 OH A:TYR766 2.8 20.2 1.0 NE2 A:HIS770 2.9 26.5 1.0 CE1 A:HIS770 3.2 30.5 1.0 CZ A:TYR766 3.6 22.3 1.0 CE2 A:TYR766 3.6 20.7 1.0 C A:PHE784 3.6 24.3 1.0 CA A:GLY787 3.7 34.3 1.0 O A:MET783 3.8 34.3 1.0 N A:GLY787 3.8 34.3 1.0 CA A:PHE784 3.9 16.2 1.0 CE2 A:PHE788 4.2 17.7 1.0 CD1 A:PHE784 4.2 25.3 1.0 CD2 A:HIS770 4.2 29.2 1.0 CD2 A:PHE788 4.3 23.1 1.0 O A:HOH11 4.3 38.5 1.0 CE1 A:HIS738 4.3 28.9 1.0 O A:HOH5 4.5 32.0 1.0 ND1 A:HIS770 4.5 32.5 1.0 C A:MET783 4.7 32.5 1.0 C A:GLY787 4.7 38.4 1.0 ND1 A:HIS738 4.7 28.7 1.0 N A:PHE784 4.8 25.0 1.0 N A:LEU785 4.8 26.6 1.0 CE1 A:TYR766 4.8 25.3 1.0 CE1 A:PHE784 4.8 25.4 1.0 CD2 A:TYR766 4.8 25.5 1.0 CG A:PHE784 5.0 19.9 1.0

J.C.Zeeh, P.C.Simister, V.Rousseau, A.Joubert, J.Cherfils, V.Biou. The SEC7 Domain Structures of Human BIG1 and CYTOHESIN1 Arf Nucleotide Exchange Factors To Be Published.