Calcium in PDB 3qfc: Crystal Structure of Human Nadph-Cytochrome P450 (V492E Mutant)

All present enzymatic activity of Crystal Structure of Human Nadph-Cytochrome P450 (V492E Mutant):
1.6.2.4;

The structure of Crystal Structure of Human Nadph-Cytochrome P450 (V492E Mutant), PDB code: 3qfc was solved by C.Xia, C.Marohnic, S.P.Panda, B.S.Masters, J.-J.P.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.42 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	70.716, 118.508, 155.360, 90.00, 90.00, 90.00
R / Rfree (%)	23.2 / 26.5

The binding sites of Calcium atom in the Crystal Structure of Human Nadph-Cytochrome P450 (V492E Mutant) (pdb code 3qfc). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of Human Nadph-Cytochrome P450 (V492E Mutant), PDB code: 3qfc:

Calcium binding site 1 out of 1 in the Crystal Structure of Human Nadph-Cytochrome P450 (V492E Mutant)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Human Nadph-Cytochrome P450 (V492E Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca762 b:28.5 occ:1.00 OD1 A:ASN595 2.5 20.0 1.0 O A:HOH1190 2.6 31.7 1.0 O A:HOH912 2.7 33.5 1.0 O A:HOH34 2.7 26.6 1.0 O A:HOH990 2.7 27.8 1.0 O A:HOH710 2.8 32.6 1.0 O A:HOH1191 2.8 39.0 1.0 CG A:ASN595 3.4 23.1 1.0 CB A:ASN595 4.2 19.4 1.0 ND2 A:ASN595 4.3 22.5 1.0 OE1 A:GLN593 4.4 24.2 1.0 OD1 A:ASP615 4.4 21.8 1.0 O A:HOH982 4.6 29.3 1.0 CA A:ASN595 4.6 19.6 1.0 O A:HOH42 4.7 26.2 1.0 O A:HOH2 4.8 37.5 1.0 OD2 A:ASP615 4.8 21.5 1.0 O A:LEU594 4.8 20.9 1.0

C.Xia, S.P.Panda, C.C.Marohnic, P.Martasek, B.S.Masters, J.J.Kim. Structural Basis For Human Nadph-Cytochrome P450 Oxidoreductase Deficiency. Proc.Natl.Acad.Sci.Usa V. 108 13486 2011.
ISSN: ISSN 0027-8424
PubMed: 21808038
DOI: 10.1073/PNAS.1106632108