Calcium in PDB 3qle: Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase

The structure of Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase, PDB code: 3qle was solved by X.G.Qian, M.Gebert, J.Hpker, M.Yan, J.Z.Li, N.Wiedemann, M.V.D.Laan, N.Pfanner, B.D.Sha, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	7.99 / 1.83
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	84.109, 84.109, 116.549, 90.00, 90.00, 120.00
R / Rfree (%)	17.5 / 20.2

The binding sites of Calcium atom in the Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase (pdb code 3qle). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase, PDB code: 3qle:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca101 b:11.5 occ:1.00 O A:ASP356 2.4 10.4 1.0 O A:ACT103 2.4 13.4 1.0 O A:VAL359 2.4 17.1 1.0 OD1 A:ASP356 2.4 12.0 1.0 C A:ASP356 3.3 11.7 1.0 C A:ACT103 3.4 21.2 1.0 CG A:ASP356 3.6 11.4 1.0 C A:VAL359 3.6 17.5 1.0 OXT A:ACT103 3.7 14.1 1.0 CA A:ASP356 3.8 11.0 1.0 CA A:CA102 3.8 12.8 1.0 CG2 A:VAL359 4.0 20.4 1.0 CB A:ASP356 4.3 10.7 1.0 CA A:LYS360 4.4 26.3 1.0 N A:LYS360 4.4 19.7 1.0 N A:HIS357 4.5 9.9 1.0 OD2 A:ASP356 4.5 10.2 1.0 N A:LYS361 4.6 27.6 1.0 N A:VAL359 4.6 10.8 1.0 CA A:VAL359 4.6 11.1 1.0 CH3 A:ACT103 4.7 18.5 1.0 O A:HOH479 4.7 12.1 0.5 OH4 A:1PE1002 4.8 29.8 0.5 CA A:HIS357 4.8 10.5 1.0 O A:PHE355 5.0 10.6 1.0 CB A:VAL359 5.0 20.7 1.0 C A:LYS360 5.0 25.8 1.0

Calcium binding site 2 out of 2 in the Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca102 b:12.8 occ:1.00 OXT A:ACT103 2.4 14.1 1.0 O A:HOH451 2.5 18.0 1.0 OD1 A:ASP356 2.5 12.0 1.0 OD2 A:ASP356 2.5 10.2 1.0 O A:HOH414 2.5 15.6 1.0 CG A:ASP356 2.8 11.4 1.0 C A:ACT103 3.4 21.2 1.0 O A:ACT103 3.7 13.4 1.0 CA A:CA101 3.8 11.5 1.0 CB A:ASP356 4.3 10.7 1.0 O A:HOH420 4.4 21.5 1.0 C23 A:1PE1002 4.5 31.3 0.5 O A:HOH481 4.5 25.0 1.0 CH3 A:ACT103 4.7 18.5 1.0 C22 A:1PE1002 4.7 31.1 0.5 O A:HOH482 4.7 18.5 1.0 O A:HOH406 4.8 21.7 1.0

X.Qian, M.Gebert, J.Hopker, M.Yan, J.Li, N.Wiedemann, M.Van Der Laan, N.Pfanner, B.Sha. Structural Basis For the Function of TIM50 in the Mitochondrial Presequence Translocase. J.Mol.Biol. V. 411 513 2011.
ISSN: ISSN 0022-2836
PubMed: 21704637
DOI: 10.1016/J.JMB.2011.06.020