Calcium in PDB 3rbz: Mthk Channel, CA2+-Bound

The structure of Mthk Channel, CA2+-Bound, PDB code: 3rbz was solved by A.B.Taylor, L.V.Parfenova, B.S.Rothberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.50 / 3.40
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	138.558, 138.558, 371.620, 90.00, 90.00, 120.00
R / Rfree (%)	25.7 / 28.8

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Calcium atom in the Mthk Channel, CA2+-Bound (pdb code 3rbz). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 12 binding sites of Calcium where determined in the Mthk Channel, CA2+-Bound, PDB code: 3rbz:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca341 b:60.2 occ:1.00 O A:ASP245 2.3 78.2 1.0 OE1 A:GLU248 2.4 76.5 1.0 OE2 A:GLU248 2.8 90.3 1.0 CD A:GLU248 2.9 86.4 1.0 O A:ARG241 3.1 87.0 1.0 C A:ASP245 3.1 66.4 1.0 N A:ASP245 3.2 93.5 1.0 CA A:ASP245 3.4 73.1 1.0 CB A:ASP245 3.6 79.5 1.0 C A:ARG241 4.1 71.6 1.0 N A:GLY246 4.3 58.0 1.0 CG A:GLU248 4.4 75.2 1.0 C A:ASP244 4.4 0.9 1.0 N A:TYR247 4.5 70.9 1.0 N A:GLU248 4.7 64.7 1.0 CB A:ASP244 4.7 0.1 1.0 C A:GLY246 4.9 60.4 1.0 CA A:SER242 4.9 55.5 1.0 N A:SER242 4.9 57.7 1.0 CA A:GLY246 4.9 60.6 1.0

Calcium binding site 2 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca342 b:60.2 occ:1.00 OD1 A:ASP184 2.3 76.6 1.0 OE1 A:GLU212 2.3 0.2 1.0 OE2 A:GLU210 2.3 70.4 1.0 OD2 A:ASP184 2.7 76.6 1.0 CG A:ASP184 2.8 76.6 1.0 CD A:GLU212 3.1 0.3 1.0 OE2 A:GLU212 3.2 0.3 1.0 CD A:GLU210 3.4 62.9 1.0 OG A:SER126 4.0 72.1 1.0 CG A:GLU210 4.1 50.6 1.0 OE1 A:GLU210 4.2 51.9 1.0 CB A:ASP184 4.3 76.6 1.0 OG A:SER124 4.3 64.9 1.0 CG A:GLU212 4.4 93.9 1.0 CB A:SER124 4.5 59.8 1.0 CB A:GLU210 4.8 32.3 1.0 O A:LEU185 4.9 74.5 1.0 CB A:SER126 4.9 58.7 1.0

Calcium binding site 3 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca343 b:60.2 occ:1.00 OD2 A:ASP305 2.4 99.4 1.0 OD1 A:ASP305 2.9 0.3 1.0 CG A:ASP305 3.0 0.7 1.0 CB A:ASP305 4.4 0.3 1.0 O A:ASP305 4.5 99.6 1.0

Calcium binding site 4 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca341 b:60.2 occ:1.00 O B:ASP245 2.1 88.0 1.0 OE1 B:GLU248 2.5 85.5 1.0 O B:ARG241 2.7 0.4 1.0 OE2 B:GLU248 2.9 99.4 1.0 CD B:GLU248 3.0 95.4 1.0 C B:ASP245 3.0 76.2 1.0 N B:ASP245 3.0 0.2 1.0 CA B:ASP245 3.3 82.9 1.0 CB B:ASP245 3.7 89.2 1.0 C B:ARG241 3.8 86.0 1.0 N B:GLY246 4.3 78.0 1.0 C B:ASP244 4.3 0.8 1.0 CG B:GLU248 4.5 84.2 1.0 N B:TYR247 4.5 83.4 1.0 CA B:SER242 4.6 74.8 1.0 CB B:ASP244 4.6 0.1 1.0 N B:SER242 4.6 77.0 1.0 CA B:ARG241 4.7 87.6 1.0 CA B:ASP244 4.8 0.2 1.0 N B:GLU248 4.8 73.8 1.0 CA B:GLY246 4.9 80.5 1.0 CB B:ARG241 4.9 78.9 1.0 C B:GLY246 4.9 80.4 1.0 N B:ASP244 4.9 0.1 1.0

Calcium binding site 5 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca342 b:60.2 occ:1.00 OE1 B:GLU212 2.0 85.9 1.0 OD1 B:ASP184 2.5 71.5 1.0 OE2 B:GLU210 2.5 82.9 1.0 OD2 B:ASP184 2.7 71.5 1.0 CD B:GLU212 2.8 0.0 1.0 CG B:ASP184 2.9 71.5 1.0 OE2 B:GLU212 3.1 98.1 1.0 CD B:GLU210 3.5 75.4 1.0 CG B:GLU212 4.2 76.7 1.0 CG B:GLU210 4.2 63.1 1.0 OG B:SER126 4.3 70.9 1.0 OE1 B:GLU210 4.3 64.4 1.0 CB B:ASP184 4.4 71.5 1.0 OG B:SER124 4.4 72.8 1.0 CB B:SER124 4.7 67.7 1.0 O B:LEU185 4.8 83.1 1.0 CB B:GLU210 5.0 44.8 1.0

Calcium binding site 6 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca343 b:60.2 occ:1.00 OD2 B:ASP305 2.8 0.3 1.0 OD1 B:ASP305 3.2 0.3 1.0 CG B:ASP305 3.4 0.6 1.0 CB B:ASP305 4.9 0.2 1.0 O B:ASP305 4.9 0.5 1.0

Calcium binding site 7 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca341 b:60.2 occ:1.00 O C:ASP245 2.2 0.2 1.0 O C:ARG241 2.6 95.5 1.0 OE1 C:GLU248 2.6 88.3 1.0 N C:ASP245 2.9 0.5 1.0 C C:ASP245 3.0 0.5 1.0 OE2 C:GLU248 3.0 0.2 1.0 CD C:GLU248 3.2 98.2 1.0 CA C:ASP245 3.3 0.2 1.0 CB C:ASP245 3.6 0.6 1.0 C C:ARG241 3.7 80.1 1.0 C C:ASP244 4.1 0.3 1.0 N C:GLY246 4.3 88.4 1.0 CB C:ASP244 4.4 0.6 1.0 CA C:SER242 4.5 80.6 1.0 N C:SER242 4.6 82.8 1.0 CA C:ASP244 4.6 0.6 1.0 CG C:GLU248 4.7 87.0 1.0 CA C:ARG241 4.7 81.7 1.0 N C:TYR247 4.7 88.2 1.0 N C:ASP244 4.7 0.6 1.0 CB C:ARG241 4.9 72.9 1.0 CA C:GLY246 4.9 90.9 1.0 C C:GLY246 5.0 90.8 1.0

Calcium binding site 8 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca342 b:60.2 occ:1.00 OE1 C:GLU212 2.2 0.8 1.0 OD1 C:ASP184 2.3 78.0 1.0 OE2 C:GLU210 2.5 78.9 1.0 OD2 C:ASP184 2.5 78.0 1.0 CG C:ASP184 2.7 78.0 1.0 CD C:GLU212 3.0 0.9 1.0 OE2 C:GLU212 3.2 1.0 1.0 CD C:GLU210 3.5 71.3 1.0 CG C:GLU210 4.2 59.1 1.0 OG C:SER126 4.2 70.6 1.0 CB C:ASP184 4.2 78.0 1.0 OG C:SER124 4.3 59.0 1.0 OE1 C:GLU210 4.3 60.3 1.0 CG C:GLU212 4.3 92.5 1.0 CB C:SER124 4.5 53.9 1.0 O C:LEU185 4.7 70.1 1.0 CB C:GLU210 4.8 40.8 1.0

Calcium binding site 9 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca343 b:60.2 occ:1.00 OD2 C:ASP305 2.8 0.8 1.0 OD1 C:ASP305 2.9 0.7 1.0 CG C:ASP305 3.2 0.1 1.0 CB C:ASP305 4.7 0.7 1.0 O C:ASP305 4.8 0.0 1.0

Calcium binding site 10 out of 12 in the Mthk Channel, CA2+-Bound


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Mthk Channel, CA2+-Bound within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca341 b:60.2 occ:1.00 OE2 D:GLU248 2.3 0.7 1.0 OE1 D:GLU248 2.4 87.9 1.0 CD D:GLU248 2.6 97.8 1.0 O D:ASP245 2.7 1.0 1.0 O D:ARG241 3.0 94.0 1.0 N D:ASP245 3.6 0.3 1.0 C D:ASP245 3.6 94.2 1.0 CA D:ASP245 3.9 0.9 1.0 C D:ARG241 4.0 78.6 1.0 CB D:ASP245 4.1 0.3 1.0 CG D:GLU248 4.1 86.6 1.0 CB D:ARG241 4.7 71.5 1.0 CA D:ARG241 4.8 80.2 1.0 C D:ASP244 4.8 0.6 1.0 N D:GLY246 4.8 79.7 1.0 N D:TYR247 4.8 88.9 1.0 N D:GLU248 4.8 76.1 1.0 CB D:ASP244 4.8 0.8 1.0 CB D:GLU248 4.9 80.6 1.0 N D:SER242 5.0 83.4 1.0

V.P.Pau, F.J.Smith, A.B.Taylor, E.Samakai, M.M.Callaghan, K.Abarca-Heidemann, L.V.Parfenova, P.J.Hart, B.S.Rothberg. Structures of Multiple CA2+-Binding Sites in A K+ Channel Rck Domain Proc.Natl.Acad.Sci.Usa 2011.
ISSN: ESSN 1091-6490