Calcium in PDB 3s9l: Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2

Protein crystallography data

The structure of Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2, PDB code: 3s9l was solved by B.E.Eckenroth, A.N.Steere, A.B.Mason, S.J.Everse, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 3.22
Space group P 43 2 2
Cell size a, b, c (Å), α, β, γ (°) 231.676, 231.676, 168.955, 90.00, 90.00, 90.00
R / Rfree (%) 27.1 / 31.4

Other elements in 3s9l:

The structure of Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2 also contains other interesting chemical elements:

Iron (Fe) 2 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2 (pdb code 3s9l). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2, PDB code: 3s9l:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in 3s9l

Go back to Calcium Binding Sites List in 3s9l
Calcium binding site 1 out of 2 in the Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca900

b:59.8
occ:1.00
O A:THR310 2.2 71.5 1.0
OE1 A:GLU468 2.3 73.8 1.0
O A:PHE313 2.4 66.0 1.0
OE1 A:GLU465 2.5 67.5 1.0
OG1 A:THR310 2.6 83.1 1.0
OE2 A:GLU465 3.0 67.5 1.0
CD A:GLU465 3.1 67.5 1.0
C A:THR310 3.2 71.5 1.0
CB A:THR310 3.3 83.1 1.0
CD A:GLU468 3.4 73.8 1.0
C A:PHE313 3.5 66.0 1.0
OE2 A:GLU468 3.8 73.8 1.0
CA A:THR310 3.9 71.5 1.0
OG A:SER315 3.9 68.5 1.0
O A:ASP307 4.0 80.7 1.0
N A:PHE313 4.1 66.0 1.0
N A:PRO311 4.3 68.0 1.0
N A:PRO314 4.3 89.2 1.0
CA A:PRO314 4.3 89.2 1.0
CA A:PHE313 4.4 66.0 1.0
N A:SER315 4.4 78.0 1.0
C A:PRO314 4.5 89.2 1.0
N A:GLY312 4.5 86.0 1.0
N A:THR310 4.5 71.5 1.0
CA A:PRO311 4.6 68.0 1.0
CB A:ASP307 4.6 73.9 1.0
CG A:GLU465 4.6 67.5 1.0
CG2 A:THR310 4.7 83.1 1.0
N A:ASP307 4.7 80.7 1.0
C A:PRO311 4.7 68.0 1.0
CG A:GLU468 4.7 73.8 1.0
C A:ASP307 4.9 80.7 1.0
CB A:GLU468 5.0 73.8 1.0
CA A:ASP307 5.0 80.7 1.0

Calcium binding site 2 out of 2 in 3s9l

Go back to Calcium Binding Sites List in 3s9l
Calcium binding site 2 out of 2 in the Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Complex Between Transferrin Receptor 1 and Transferrin with Iron in the N-Lobe, Cryocooled 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca900

b:79.2
occ:1.00
OE1 B:GLU468 2.1 87.9 1.0
O B:THR310 2.1 71.0 1.0
OE1 B:GLU465 2.4 88.6 1.0
OE2 B:GLU465 2.4 88.6 1.0
OG1 B:THR310 2.6 63.2 1.0
CD B:GLU465 2.7 88.6 1.0
O B:PHE313 2.7 0.1 1.0
C B:THR310 3.3 71.0 1.0
CD B:GLU468 3.3 87.9 1.0
CB B:THR310 3.5 63.2 1.0
C B:PHE313 3.6 0.1 1.0
CA B:PRO314 3.8 92.5 1.0
OE2 B:GLU468 3.9 87.9 1.0
OG B:SER315 4.0 87.0 1.0
CA B:THR310 4.1 71.0 1.0
O B:ASP307 4.1 0.1 1.0
C B:PRO314 4.1 92.5 1.0
N B:PRO314 4.1 92.5 1.0
N B:SER315 4.2 0.8 1.0
CG B:GLU465 4.2 88.6 1.0
N B:PRO311 4.4 0.3 1.0
CG B:GLU468 4.5 87.9 1.0
N B:ASP307 4.5 0.1 1.0
CB B:ASP307 4.5 0.8 1.0
CA B:PRO311 4.6 0.3 1.0
N B:PHE313 4.6 0.1 1.0
CB B:GLU468 4.7 87.9 1.0
N B:GLY312 4.7 0.3 1.0
CA B:GLU465 4.8 96.5 1.0
CA B:PHE313 4.8 0.1 1.0
O B:PRO314 4.8 92.5 1.0
CG2 B:THR310 4.9 63.2 1.0
N B:THR310 4.9 71.0 1.0
C B:PRO311 4.9 0.3 1.0
CA B:ASP307 4.9 0.1 1.0
CB B:GLU465 4.9 88.6 1.0
C B:ASP307 5.0 0.1 1.0
CB B:SER315 5.0 87.0 1.0

Reference:

B.E.Eckenroth, A.N.Steere, N.D.Chasteen, S.J.Everse, A.B.Mason. How the Binding of Human Transferrin Primes the Transferrin Receptor Potentiating Iron Release at Endosomal pH. Proc.Natl.Acad.Sci.Usa V. 108 13089 2011.
ISSN: ISSN 0027-8424
PubMed: 21788477
DOI: 10.1073/PNAS.1105786108
Page generated: Sat Dec 12 04:29:36 2020

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