Calcium in PDB 3sal: Crystal Structure of Influenza A Virus Neuraminidase N5

All present enzymatic activity of Crystal Structure of Influenza A Virus Neuraminidase N5:
3.2.1.18;

The structure of Crystal Structure of Influenza A Virus Neuraminidase N5, PDB code: 3sal was solved by M.Y.Wang, J.X.Qi, Y.Liu, C.J.Vavricka, Y.Wu, Q.Li, G.F.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.17 / 1.50
Space group	P 4
Cell size a, b, c (Å), α, β, γ (°)	111.513, 111.513, 66.465, 90.00, 90.00, 90.00
R / Rfree (%)	12.6 / 16.4

The binding sites of Calcium atom in the Crystal Structure of Influenza A Virus Neuraminidase N5 (pdb code 3sal). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Influenza A Virus Neuraminidase N5, PDB code: 3sal:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Influenza A Virus Neuraminidase N5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Influenza A Virus Neuraminidase N5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca601 b:11.9 occ:1.00 OD2 A:ASP324 2.4 12.4 1.0 O A:ASP293 2.4 11.2 1.0 O A:TYR347 2.4 12.0 1.0 O A:GLY297 2.5 12.2 1.0 O A:HOH9 2.5 14.9 1.0 O A:HOH11 2.5 14.3 1.0 CG A:ASP324 3.6 12.5 1.0 C A:ASP293 3.6 11.3 1.0 C A:GLY297 3.6 12.7 1.0 C A:TYR347 3.6 11.5 1.0 CA A:GLY348 3.9 10.8 1.0 O A:HOH19 4.0 12.8 1.0 N A:GLY348 4.2 11.4 1.0 CA A:MET298 4.3 12.6 1.0 O A:THR346 4.3 13.3 1.0 O A:HOH55 4.3 15.0 1.0 N A:MET298 4.3 12.7 1.0 OD1 A:ASP324 4.4 12.6 1.0 CB A:ASP324 4.4 12.6 1.0 CA A:ASN294 4.4 12.2 1.0 N A:ASN294 4.4 11.8 1.0 OD1 A:ASP293 4.5 13.7 1.0 CA A:ASP293 4.5 11.9 1.0 CB A:ASP293 4.6 12.8 1.0 CA A:GLY297 4.6 12.2 1.0 N A:GLY297 4.7 12.4 1.0 N A:TYR347 4.7 12.1 1.0 N A:ASP293 4.7 11.7 1.0 CA A:TYR347 4.8 12.6 1.0 C A:ASN294 4.8 12.0 1.0 N A:TRP295 4.8 11.9 1.0 CG A:ASP293 5.0 13.9 1.0 O A:PRO326 5.0 12.4 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Influenza A Virus Neuraminidase N5


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Influenza A Virus Neuraminidase N5 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca601 b:10.7 occ:1.00 O B:ASP293 2.4 11.4 1.0 OD2 B:ASP324 2.4 13.0 1.0 O B:TYR347 2.4 12.6 1.0 O B:GLY297 2.4 11.9 1.0 O B:HOH45 2.5 13.0 1.0 O B:HOH6 2.5 13.3 1.0 CG B:ASP324 3.5 12.5 1.0 C B:ASP293 3.6 10.7 1.0 C B:TYR347 3.6 12.1 1.0 C B:GLY297 3.6 12.5 1.0 CA B:GLY348 3.9 9.9 1.0 O B:HOH31 4.0 13.4 1.0 N B:GLY348 4.2 10.8 1.0 O B:HOH42 4.2 13.3 1.0 CA B:MET298 4.3 13.5 1.0 O B:THR346 4.3 12.8 1.0 N B:MET298 4.3 13.2 1.0 CA B:ASN294 4.3 12.2 1.0 OD1 B:ASP324 4.4 11.6 1.0 CB B:ASP324 4.4 11.6 1.0 N B:ASN294 4.4 10.7 1.0 OD1 B:ASP293 4.5 12.1 1.0 CA B:ASP293 4.5 10.6 1.0 CA B:GLY297 4.6 12.1 1.0 CB B:ASP293 4.6 11.6 1.0 N B:GLY297 4.6 12.3 1.0 N B:TYR347 4.7 12.1 1.0 N B:ASP293 4.7 10.5 1.0 CA B:TYR347 4.8 12.1 1.0 C B:ASN294 4.8 11.8 1.0 N B:TRP295 4.8 10.7 1.0 O B:PRO326 5.0 13.7 1.0 CG B:ASP293 5.0 12.1 1.0

M.Y.Wang, J.X.Qi, Y.Liu, C.J.Vavricka, Y.Wu, Q.Li, G.F.Gao. Influenza A Virus N5 Neuraminidase Has An Extended 150-Cavity J.Virol. V. 85 8431 2011.
ISSN: ISSN 0022-538X
PubMed: 21653672
DOI: 10.1128/JVI.00638-11