Calcium in PDB 4afc: Crystal Structure of Subtype-Switched Epithelial Adhesin 1 to 6 A Domain (EPA1TO6A) From Candida Glabrata in Complex with GALB1-3GLC

The structure of Crystal Structure of Subtype-Switched Epithelial Adhesin 1 to 6 A Domain (EPA1TO6A) From Candida Glabrata in Complex with GALB1-3GLC, PDB code: 4afc was solved by M.Maestre-Reyna, R.Diderrich, M.S.Veelders, G.Eulenburg, V.Kalugin, S.Brueckner, P.Keller, S.Rupp, H.-U.Moesch, L.-O.Essen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.62 / 1.55
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	74.430, 103.890, 69.280, 90.00, 90.00, 90.00
R / Rfree (%)	14.355 / 17.146

The binding sites of Calcium atom in the Crystal Structure of Subtype-Switched Epithelial Adhesin 1 to 6 A Domain (EPA1TO6A) From Candida Glabrata in Complex with GALB1-3GLC (pdb code 4afc). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of Subtype-Switched Epithelial Adhesin 1 to 6 A Domain (EPA1TO6A) From Candida Glabrata in Complex with GALB1-3GLC, PDB code: 4afc:

Calcium binding site 1 out of 1 in the Crystal Structure of Subtype-Switched Epithelial Adhesin 1 to 6 A Domain (EPA1TO6A) From Candida Glabrata in Complex with GALB1-3GLC


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Subtype-Switched Epithelial Adhesin 1 to 6 A Domain (EPA1TO6A) From Candida Glabrata in Complex with GALB1-3GLC within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1267 b:12.0 occ:1.00 OD1 A:ASP164 2.3 11.8 1.0 OD1 A:ASN225 2.3 11.2 1.0 O A:ASP227 2.3 12.4 1.0 O A:ASP229 2.3 12.3 1.0 O3 A:GAL1268 2.4 13.5 1.0 OD2 A:ASP165 2.4 12.9 1.0 O4 A:GAL1268 2.5 13.5 1.0 CG A:ASP164 3.3 14.8 1.0 C4 A:GAL1268 3.3 13.6 1.0 CG A:ASP165 3.3 12.6 1.0 C3 A:GAL1268 3.3 13.5 1.0 CG A:ASN225 3.4 12.8 1.0 C A:ASP227 3.5 13.3 1.0 C A:ASP229 3.6 11.7 1.0 OD2 A:ASP164 3.6 15.3 1.0 OD1 A:ASP165 3.7 13.0 1.0 N A:ASP227 4.0 12.8 1.0 ND2 A:ASN225 4.0 12.5 1.0 C2 A:GAL1268 4.1 15.3 1.0 N A:ASP229 4.1 14.1 1.0 C A:ASN228 4.1 12.8 0.5 C A:ASN228 4.2 14.4 0.5 O A:ASN228 4.3 12.3 0.5 CA A:ASP227 4.3 13.6 1.0 C A:ASP164 4.3 10.7 1.0 N A:ARG226 4.3 12.0 1.0 N A:ASP165 4.4 11.7 1.0 O A:ASP164 4.4 11.6 1.0 CA A:ASP229 4.5 13.4 1.0 O A:ASN228 4.5 12.7 0.5 CB A:ASP165 4.5 13.1 1.0 N A:ASN228 4.5 14.1 0.5 N A:ASN228 4.5 12.6 0.5 CB A:ASP164 4.5 12.9 1.0 N A:GLY230 4.6 12.8 1.0 CB A:ASN228 4.6 16.3 0.5 CB A:ASN225 4.7 11.3 1.0 CA A:GLY230 4.7 13.1 1.0 CA A:ASN228 4.7 15.3 0.5 CA A:ASN228 4.7 13.0 0.5 C5 A:GAL1268 4.7 17.6 1.0 CA A:ASN225 4.7 10.4 1.0 CB A:ASP227 4.7 12.4 1.0 CB A:ASN228 4.7 11.7 0.5 CG A:ARG226 4.8 13.7 1.0 CA A:ASP165 4.8 11.1 1.0 CA A:ASP164 4.9 11.4 1.0 O2 A:GAL1268 4.9 14.9 1.0 C A:ASN225 5.0 11.4 1.0

M.Maestre-Reyna, R.Diderrich, M.S.Veelders, G.Eulenburg, V.Kalugin, S.Bruckner, P.Keller, S.Rupp, H.Mosch, L.Essen. Structural Basis For Promiscuity and Specificity During Candida Glabrata Invasion of Host Epithelia. Proc.Natl.Acad.Sci.Usa V. 109 16864 2012.
ISSN: ISSN 0027-8424
PubMed: 23035251
DOI: 10.1073/PNAS.1207653109