Calcium in PDB 4b7n: H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained By Kinetic and Structural Analysis

The structure of H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained By Kinetic and Structural Analysis, PDB code: 4b7n was solved by E.Van Der Vries, S.G.Vachieri, X.Xiong, J.Liu, P.J.Collins, P.A.Walker, L.F.Haire, A.J.Hay, M.Schutten, A.D.M.E.Osterhaus, S.R.Martin, C.A.B.Boucher, J.J.Skehel, S.J.Gamblin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	83.62 / 2.84
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	118.350, 118.350, 68.380, 90.00, 90.00, 90.00
R / Rfree (%)	18.513 / 22.401

The binding sites of Calcium atom in the H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained By Kinetic and Structural Analysis (pdb code 4b7n). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained By Kinetic and Structural Analysis, PDB code: 4b7n:

Calcium binding site 1 out of 1 in the H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained By Kinetic and Structural Analysis


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained By Kinetic and Structural Analysis within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca701 b:20.5 occ:1.00 O A:ASP294 2.3 12.4 1.0 O A:HOH2081 2.4 18.8 1.0 O A:ASN344 2.4 16.1 1.0 O A:GLY298 2.5 13.2 1.0 OD2 A:ASP324 2.8 13.5 1.0 O A:GLY342 2.8 19.3 1.0 C A:ASP294 3.5 12.3 1.0 C A:GLY298 3.5 13.2 1.0 C A:ASN344 3.6 16.1 1.0 CG A:ASP324 3.7 13.6 1.0 C A:GLY342 3.9 19.2 1.0 CA A:GLY345 3.9 14.5 1.0 O A:HOH2070 4.1 11.5 1.0 CA A:ASN295 4.2 12.4 1.0 N A:GLY345 4.2 15.3 1.0 N A:ASN295 4.3 12.3 1.0 N A:GLY298 4.3 12.9 1.0 N A:SER299 4.3 13.0 1.0 CB A:ASP324 4.3 13.5 1.0 CA A:SER299 4.4 13.0 1.0 CA A:GLY298 4.4 13.0 1.0 O A:ALA343 4.4 17.6 1.0 CA A:ASP294 4.5 12.1 1.0 OD1 A:ASP324 4.5 13.5 1.0 C A:ALA343 4.5 17.7 1.0 CA A:GLY342 4.6 19.6 1.0 C A:ASN295 4.6 12.4 1.0 CB A:ASP294 4.7 12.1 1.0 N A:ASP294 4.7 11.9 1.0 N A:ASN344 4.7 17.3 1.0 CA A:ASN344 4.8 16.7 1.0 O A:ASN295 4.9 12.4 1.0 N A:ALA343 4.9 18.7 1.0 OD1 A:ASP294 4.9 12.1 1.0

E.Van Der Vries, P.J.Collins, S.G.Vachieri, X.Xiong, J.Liu, P.A.Walker, L.F.Haire, A.J.Hay, M.Schutten, A.D.M.E.Osterhaus, S.R.Martin, C.A.B.Boucher, J.J.Skehel, S.J.Gamblin. H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained By Kinetic and Structural Analysis Plos Pathog. V. 8 2914 2012.
ISSN: ISSN 1553-7366
PubMed: 23028314
DOI: 10.1371/JOURNAL.PPAT.1002914