Calcium in PDB 4bxo: Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex

All present enzymatic activity of Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex:
3.6.4.13;

The structure of Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex, PDB code: 4bxo was solved by R.Coulthard, A.Deans, P.Swuec, M.Bowles, A.Purkiss, A.Costa, S.West, N.Mcdonald, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.43 / 2.15
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	125.100, 125.100, 74.760, 90.00, 90.00, 90.00
R / Rfree (%)	20.36 / 25.523

The binding sites of Calcium atom in the Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex (pdb code 4bxo). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex, PDB code: 4bxo:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2050 b:33.0 occ:1.00 O A:HOH3017 2.2 20.1 1.0 OD2 A:ASP1854 2.2 27.1 1.0 O A:ARG1865 2.3 28.6 1.0 OE2 A:GLU1864 2.7 35.9 1.0 CG A:ASP1854 3.1 28.2 1.0 OD1 A:ASP1854 3.2 27.5 1.0 O A:HOH3009 3.3 22.9 1.0 C A:ARG1865 3.4 27.8 1.0 CD A:GLU1864 3.7 32.6 1.0 N A:ARG1865 4.0 27.6 1.0 CA A:ARG1865 4.1 27.5 1.0 CB A:ARG1865 4.3 27.6 1.0 OE2 A:GLU1826 4.3 31.1 1.0 OE1 A:GLU1864 4.4 33.1 1.0 CB A:ASP1854 4.4 26.4 1.0 CG A:GLU1864 4.5 29.3 1.0 NH1 A:ARG1866 4.5 40.1 1.0 N A:ARG1866 4.5 27.8 1.0 CD A:ARG1866 4.6 35.6 1.0 CA A:ARG1866 4.8 30.4 1.0 C A:GLU1864 4.9 27.9 1.0

Calcium binding site 2 out of 4 in the Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1215 b:34.1 occ:1.00 O B:HOH2009 2.2 14.9 1.0 OD2 B:ASP44 2.4 44.5 1.0 OD1 B:ASP44 2.7 38.6 1.0 CG B:ASP44 2.9 42.4 1.0 O B:HOH2010 4.2 16.8 1.0 CB B:ASP44 4.4 40.8 1.0 OE2 B:GLU43 4.8 43.4 1.0

Calcium binding site 3 out of 4 in the Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1216 b:32.7 occ:1.00 O B:GLN164 2.3 28.8 1.0 O B:HOH2032 2.4 21.5 1.0 O B:HOH2031 2.4 19.4 1.0 OP2 I:DT7 2.4 39.6 1.0 O B:VAL169 2.5 28.0 1.0 C B:GLN164 3.4 28.0 1.0 C B:VAL169 3.6 28.9 1.0 P I:DT7 3.7 39.5 1.0 CA B:GLN164 4.0 28.1 1.0 OP1 I:DT7 4.1 39.2 1.0 CB B:GLN164 4.2 29.5 1.0 CA B:GLY170 4.3 30.9 1.0 N B:GLY170 4.3 29.8 1.0 O B:ILE166 4.4 27.3 1.0 N B:GLN165 4.5 27.4 1.0 O5' I:DT7 4.6 43.5 1.0 N B:VAL169 4.7 29.0 1.0 O3' I:DA6 4.7 36.1 1.0 CA B:VAL169 4.7 28.1 1.0 CA B:GLN165 4.7 28.7 1.0 C3' I:DA6 4.8 37.0 1.0 C B:GLN165 5.0 27.2 1.0

Calcium binding site 4 out of 4 in the Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1217 b:35.5 occ:1.00 O B:GLU196 2.3 33.0 1.0 OP1 H:DA11 2.4 40.4 1.0 O B:VAL199 2.5 29.4 1.0 C B:GLU196 3.3 32.8 1.0 C B:VAL199 3.5 30.7 1.0 P H:DA11 3.6 46.7 1.0 CA B:GLU196 3.9 32.0 1.0 CA B:GLY200 4.1 33.1 1.0 N B:GLY200 4.1 31.5 1.0 OP2 H:DA11 4.1 45.6 1.0 CB B:GLU196 4.3 33.8 1.0 O5' H:DA11 4.3 45.6 1.0 N B:VAL199 4.4 29.0 1.0 N B:GLN197 4.4 32.3 1.0 CA B:VAL199 4.5 28.6 1.0 C B:GLN197 4.7 33.4 1.0 C B:GLY200 4.8 33.6 1.0 CA B:GLN197 4.8 34.0 1.0 N B:VAL198 4.8 30.4 1.0 C B:VAL198 4.8 29.3 1.0 O3' H:DG10 4.8 45.9 1.0 CG B:GLU196 4.9 36.1 1.0 C5' H:DA11 4.9 47.6 1.0

R.Coulthard, A.J.Deans, P.Swuec, M.Bowles, A.Costa, S.C.West, N.Q.Mcdonald. Architecture and Dna Recognition Elements of the Fanconi Anemia Fancm-FAAP24 Complex. Structure V. 21 1648 2013.
ISSN: ISSN 0969-2126
PubMed: 23932590
DOI: 10.1016/J.STR.2013.07.006