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Calcium in PDB 4dfr: Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate
Enzymatic activity of Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate
All present enzymatic activity of Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate:
1.5.1.3;
1.5.1.3;
Protein crystallography data
The structure of Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate, PDB code: 4dfr
was solved by
D.J.Filman,
D.A.Matthews,
J.T.Bolin,
J.Kraut,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | N/A / 1.70 |
| Space group | P 61 |
| Cell size a, b, c (Å), α, β, γ (°) | 93.220, 93.220, 73.560, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 15.5 / n/a |
Other elements in 4dfr:
The structure of Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate also contains other interesting chemical elements:
| Chlorine | (Cl) | 2 atoms |
Calcium Binding Sites:
The binding sites of Calcium atom in the Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate
(pdb code 4dfr). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate, PDB code: 4dfr:
In total only one binding site of Calcium was determined in the Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate, PDB code: 4dfr:
Calcium binding site 1 out of 1 in 4dfr
Go back to
Calcium Binding Sites List in 4dfr
Calcium binding site 1 out
of 1 in the Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 Angstroms Resolution. I. General Features and Binding of Methotrexate within 5.0Å range:
|
Reference:
J.T.Bolin,
D.J.Filman,
D.A.Matthews,
R.C.Hamlin,
J.Kraut.
Crystal Structures of Escherichia Coli and Lactobacillus Casei Dihydrofolate Reductase Refined at 1.7 A Resolution. I. General Features and Binding of Methotrexate. J.Biol.Chem. V. 257 13650 1982.
ISSN: ISSN 0021-9258
PubMed: 6815178
Page generated: Sat Jul 13 23:25:57 2024
ISSN: ISSN 0021-9258
PubMed: 6815178
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