Calcium in PDB 4dxw: Crystal Structure of Navrh, A Voltage-Gated Sodium Channel

The structure of Crystal Structure of Navrh, A Voltage-Gated Sodium Channel, PDB code: 4dxw was solved by X.Zhang, W.L.Ren, C.Y.Yan, J.W.Wang, N.Yan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.33 / 3.05
Space group	P 42
Cell size a, b, c (Å), α, β, γ (°)	163.437, 163.437, 61.071, 90.00, 90.00, 90.00
R / Rfree (%)	23.7 / 26.8

The binding sites of Calcium atom in the Crystal Structure of Navrh, A Voltage-Gated Sodium Channel (pdb code 4dxw). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Navrh, A Voltage-Gated Sodium Channel, PDB code: 4dxw:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Navrh, A Voltage-Gated Sodium Channel


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Navrh, A Voltage-Gated Sodium Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca303 b:87.3 occ:1.00 O A:LYS226 3.0 70.5 1.0 CA A:LYS227 3.7 72.3 1.0 C A:LYS226 3.9 74.4 1.0 N A:LEU228 4.0 91.4 1.0 C A:LYS227 4.0 81.1 1.0 N A:LYS227 4.3 69.0 1.0 O A:LEU228 4.3 85.0 1.0 CB A:LYS227 4.8 70.3 1.0 CG A:LYS227 4.8 70.8 1.0 O A:LYS227 4.8 78.7 1.0 CA A:LEU228 5.0 87.6 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Navrh, A Voltage-Gated Sodium Channel


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Navrh, A Voltage-Gated Sodium Channel within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca302 b:63.5 occ:1.00 O B:HOH401 2.1 81.1 0.8 O A:HOH402 2.3 51.8 1.0 O A:HOH403 2.3 54.0 0.8 O C:HOH401 2.4 42.1 0.7 O A:HOH401 2.4 48.6 0.8 O C:HOH402 2.5 99.1 1.0 O C:LEU179 3.9 57.5 1.0 O B:THR178 4.3 60.1 1.0 O A:LEU179 4.5 47.4 1.0 O B:LEU179 4.5 60.9 1.0 O C:THR178 4.5 54.9 1.0 O A:THR178 4.6 51.8 1.0 C C:LEU179 4.8 54.2 1.0 O D:LEU179 4.8 44.4 1.0 CB B:LEU179 4.9 56.2 1.0 O D:THR178 4.9 49.1 1.0 C B:LEU179 4.9 59.3 1.0 C A:LEU179 5.0 43.6 1.0 CB C:LEU179 5.0 52.9 1.0

X.Zhang, W.L.Ren, P.Decaen, C.Y.Yan, X.Tao, L.Tang, J.J.Wang, K.Hasegawa, T.Kumasaka, J.H.He, J.W.Wang, D.E.Clapham, N.Yan. Crystal Structure of An Orthologue of the Nachbac Voltage-Gated Sodium Channel Nature V. 486 130 2012.
ISSN: ISSN 0028-0836
PubMed: 22678295
DOI: 10.1038/NATURE11054