Calcium in PDB 4dyx: Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star

All present enzymatic activity of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star:
1.16.3.1;

The structure of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star, PDB code: 4dyx was solved by F.A.Tezcan, D.J.E.Huard, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	51.78 / 1.85
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	179.268, 179.268, 179.268, 90.00, 90.00, 90.00
R / Rfree (%)	16.9 / 19.7

The structure of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star also contains other interesting chemical elements:

Copper

(Cu)

4 atoms

The binding sites of Calcium atom in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star (pdb code 4dyx). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star, PDB code: 4dyx:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca205 b:20.9 occ:0.50 OE1 A:GLN86 2.3 19.6 1.0 CD A:GLN86 3.3 18.0 1.0 NE2 A:GLN86 3.8 19.0 1.0 O A:HOH333 4.0 21.1 1.0 CG A:GLN86 4.7 17.4 1.0 CG A:LYS87 4.7 18.6 1.0 CB A:GLN86 4.9 16.7 1.0 N A:LYS87 5.0 17.1 1.0 CA A:GLN86 5.0 16.5 1.0

Calcium binding site 2 out of 3 in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca206 b:50.8 occ:0.33 CA A:CA207 1.9 64.0 0.3 OE1 A:GLU134 2.4 21.2 1.0 OD1 A:ASP131 2.8 21.0 1.0 O A:HOH448 3.2 39.6 1.0 CD A:GLU134 3.6 19.8 1.0 CG A:ASP131 4.0 18.4 1.0 O A:HOH449 4.0 33.6 1.0 OE2 A:GLU134 4.2 20.4 1.0 CB A:ASP131 4.6 16.9 1.0 CB A:GLU134 4.7 17.4 1.0 CG A:GLU134 4.7 18.3 1.0 CA A:ASP131 4.9 16.4 1.0 OD2 A:ASP131 4.9 20.3 1.0

Calcium binding site 3 out of 3 in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant 4HIS- Delta C-Star within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca207 b:64.0 occ:0.33 CA A:CA206 1.9 50.8 0.3 O A:HOH449 2.4 33.6 1.0 OD1 A:ASP131 2.4 21.0 1.0 OE1 A:GLU134 3.5 21.2 1.0 CG A:ASP131 3.6 18.4 1.0 OD2 A:ASP131 4.1 20.3 1.0 OG1 A:THR135 4.4 18.4 1.0 CD A:GLU134 4.7 19.8 1.0 CB A:ASP131 4.7 16.9 1.0 CB A:GLU134 4.8 17.4 1.0 O A:HOH448 4.9 39.6 1.0

D.J.Huard, K.M.Kane, F.A.Tezcan. Re-Engineering Protein Interfaces Yields Copper-Inducible Ferritin Cage Assembly. Nat.Chem.Biol. V. 9 169 2013.
ISSN: ISSN 1552-4450
PubMed: 23340339
DOI: 10.1038/NCHEMBIO.1163