Calcium in PDB 4dyy: Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1

All present enzymatic activity of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1:
1.16.3.1;

The structure of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1, PDB code: 4dyy was solved by F.A.Tezcan, D.J.E.Huard, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	89.80 / 1.90
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	179.594, 179.594, 179.594, 90.00, 90.00, 90.00
R / Rfree (%)	21.8 / 24.1

The structure of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1 also contains other interesting chemical elements:

Copper

(Cu)

3 atoms

The binding sites of Calcium atom in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1 (pdb code 4dyy). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1, PDB code: 4dyy:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca204 b:40.1 occ:0.50 O A:HOH409 2.3 29.4 1.0 OE1 A:GLN86 2.5 33.1 1.0 O A:HOH408 3.2 38.2 1.0 CD A:GLN86 3.7 31.5 1.0 NE2 A:GLN86 4.3 32.7 1.0 CG A:GLN86 4.9 30.5 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Cu-Adduct of Human H-Ferritin Variant MIC1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca205 b:46.6 occ:0.33 OE1 A:GLU134 2.5 31.0 1.0 OD1 A:ASP131 2.6 32.9 1.0 O A:HOH446 2.9 63.5 0.3 CG A:ASP131 3.7 29.8 1.0 CD A:GLU134 3.8 30.4 1.0 O A:HOH417 4.0 66.4 0.3 CB A:ASP131 4.5 27.9 1.0 OE2 A:GLU134 4.5 31.2 1.0 CB A:GLU134 4.6 27.9 1.0 OD2 A:ASP131 4.7 30.8 1.0 CG A:GLU134 4.7 28.7 1.0 CA A:ASP131 4.8 27.6 1.0

D.J.Huard, K.M.Kane, F.A.Tezcan. Re-Engineering Protein Interfaces Yields Copper-Inducible Ferritin Cage Assembly. Nat.Chem.Biol. V. 9 169 2013.
ISSN: ISSN 1552-4450
PubMed: 23340339
DOI: 10.1038/NCHEMBIO.1163