Calcium in PDB 4epu: ANG1 Fibrinogen-Related Domain (Fred)

The structure of ANG1 Fibrinogen-Related Domain (Fred), PDB code: 4epu was solved by C.C.Yeykal, E.J.Adams, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.44 / 2.10
Space group	P 64
Cell size a, b, c (Å), α, β, γ (°)	80.903, 80.903, 186.087, 90.00, 90.00, 120.00
R / Rfree (%)	18.3 / 20.1

The binding sites of Calcium atom in the ANG1 Fibrinogen-Related Domain (Fred) (pdb code 4epu). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the ANG1 Fibrinogen-Related Domain (Fred), PDB code: 4epu:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the ANG1 Fibrinogen-Related Domain (Fred)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of ANG1 Fibrinogen-Related Domain (Fred) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca601 b:52.9 occ:1.00 O A:CYS437 2.4 31.9 1.0 O A:HOH749 2.4 33.4 1.0 OD1 A:ASP433 2.4 27.5 1.0 OD1 A:ASP431 2.5 31.6 1.0 O A:CYS435 2.6 32.6 1.0 O A:HOH711 2.6 29.4 1.0 CG A:ASP431 3.2 37.4 1.0 OD2 A:ASP431 3.2 40.2 1.0 CG A:ASP433 3.3 25.3 1.0 O A:HOH780 3.4 48.0 1.0 OD2 A:ASP433 3.5 29.3 1.0 C A:CYS435 3.5 34.0 1.0 C A:CYS437 3.6 33.5 1.0 O A:MET436 4.1 48.0 1.0 C A:MET436 4.1 40.5 1.0 CA A:CYS435 4.2 28.6 1.0 CB A:CYS435 4.2 25.7 1.0 N A:CYS435 4.2 29.9 1.0 O A:ASP433 4.3 31.8 1.0 N A:CYS437 4.3 35.0 1.0 CA A:LYS438 4.3 33.7 1.0 N A:LYS438 4.4 32.4 1.0 N A:MET436 4.4 35.0 1.0 CA A:MET436 4.5 38.0 1.0 CG A:LYS438 4.5 41.8 1.0 N A:ASP433 4.6 26.6 1.0 CB A:ASP433 4.6 22.9 1.0 CA A:CYS437 4.6 30.9 1.0 C A:ASP433 4.6 26.3 1.0 CB A:ASP431 4.7 32.4 1.0 O A:ASP431 4.8 29.4 1.0 CA A:ASP433 4.8 24.8 1.0 O A:HOH782 4.8 56.1 1.0 O A:HOH753 4.9 48.1 1.0 C A:ASP431 4.9 28.5 1.0

Calcium binding site 2 out of 2 in the ANG1 Fibrinogen-Related Domain (Fred)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of ANG1 Fibrinogen-Related Domain (Fred) within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca601 b:71.9 occ:1.00 O B:CYS437 2.1 32.2 1.0 OD1 B:ASP433 2.3 25.9 1.0 O B:HOH795 2.4 53.6 1.0 OD1 B:ASP431 2.6 31.2 1.0 O B:CYS435 2.6 32.9 1.0 O B:HOH756 2.9 27.9 1.0 CG B:ASP433 3.1 25.1 1.0 OD2 B:ASP433 3.2 29.6 1.0 C B:CYS437 3.3 33.8 1.0 CG B:ASP431 3.4 37.0 1.0 OD2 B:ASP431 3.4 39.5 1.0 C B:CYS435 3.4 34.5 1.0 CB B:CYS435 4.0 25.9 1.0 C B:MET436 4.0 40.8 1.0 O B:MET436 4.1 47.6 1.0 CA B:CYS435 4.1 28.5 1.0 CA B:LYS438 4.1 33.7 1.0 N B:CYS435 4.1 30.2 1.0 N B:LYS438 4.2 31.8 1.0 N B:CYS437 4.2 36.2 1.0 N B:MET436 4.4 35.0 1.0 CA B:CYS437 4.4 30.3 1.0 CG B:LYS438 4.4 42.1 1.0 O B:ASP433 4.4 31.1 1.0 CB B:ASP433 4.5 22.9 1.0 CA B:MET436 4.5 37.9 1.0 N B:ASP433 4.6 27.3 1.0 C B:ASP433 4.7 25.4 1.0 CA B:ASP433 4.8 24.4 1.0 CB B:ASP431 4.8 32.8 1.0 N B:CYS439 4.8 28.1 1.0 CB B:LYS438 4.9 38.6 1.0 O B:ASP431 5.0 29.2 1.0 O B:HOH725 5.0 29.5 1.0

C.C.Yeykal, L.Sundaresan, M.Mrksich, E.J.Adams. Biochemical and Structural Characterization of the ANG1 Fibrinogen-Related Domain To Be Published.